Zobrazeno 1 - 10
of 109
pro vyhledávání: '"András Kotschy"'
Autor:
Szilárd Tóth, Márton F. Szlávik, Réka Mandel, Fanni Fekecs, Gábor Tusnády, Flóra Vajda, Nóra Varga, Ágota Apáti, Attila Bényei, Attila Paczal, András Kotschy, Gergely Szakács
Publikováno v:
ACS Omega, Vol 9, Iss 29, Pp 32226-32234 (2024)
Externí odkaz:
https://doaj.org/article/79a1802ae16c4eafaec39a09939a8c03
Autor:
Szabolcs Sipos, Balázs Bálint, Zoltán B. Szabó, Levente Ondi, Márton Csékei, Zoltán Szlávik, Ágnes Proszenyák, James B. Murray, James Davidson, Ijen Chen, Pawel Dokurno, Allan E. Surgenor, Christopher Pedder, Roderick E. Hubbard, Ana-Leticia Maragno, Maia Chanrion, Frederic Colland, Olivier Geneste, András Kotschy
Publikováno v:
ACS Omega, Vol 6, Iss 34, Pp 22073-22102 (2021)
Externí odkaz:
https://doaj.org/article/8920fac56cd04386b0126955f672d5f2
Autor:
James B. Murray, James Davidson, Ijen Chen, Ben Davis, Pawel Dokurno, Christopher J. Graham, Richard Harris, Allan Jordan, Natalia Matassova, Christopher Pedder, Stuart Ray, Stephen D. Roughley, Julia Smith, Claire Walmsley, Yikang Wang, Neil Whitehead, Douglas S. Williamson, Patrick Casara, Thierry Le Diguarher, John Hickman, Jerome Stark, András Kotschy, Olivier Geneste, Roderick E. Hubbard
Publikováno v:
ACS Omega, Vol 4, Iss 5, Pp 8892-8906 (2019)
Externí odkaz:
https://doaj.org/article/10eb0acc389644bbabfc95caab03b58a
Publikováno v:
ARKIVOC, Vol 2004, Iss 7, Pp 285-291 (2004)
Externí odkaz:
https://doaj.org/article/e888c1e592f644fc809dcc83bd0ceab7
Autor:
Márton Zwillinger, Lucile Fischer, Gergő Sályi, Soma Szabó, Márton Csékei, Ivan Huc, András Kotschy
Publikováno v:
Journal of the American Chemical Society. 144:19078-19088
Information storage at the molecular level commonly entails encoding in the form of ordered sequences of different monomers and subsequent fragmentation and tandem mass spectrometry analysis to read this information. Recent approaches also include th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ee8c4e5b527c817bfcad55c4544abc
https://doi.org/10.1021/jacs.2c08135
https://doi.org/10.1021/jacs.2c08135
Publikováno v:
Journal of Cellular and Molecular Medicine
The dual‐specificity tyrosine‐regulated kinases DYRK1A and DYRK1B play a key role in controlling the quiescence‐proliferation switch in cancer cells. Serum reduction of U87MG 2D cultures or multi‐cellular tumour spheroids induced a quiescent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f43e2d1ac074923f3c78a3b89f027a0
https://doi.org/10.1111/jcmm.17002
https://doi.org/10.1111/jcmm.17002
Autor:
András Kotschy
Publikováno v:
Scientia et Securitas. 2:177-183
Összefoglaló. A betegségek mögött meghúzódó biokémiai, sejtbiológiai változások molekuláris szintű megértése a korszerű gyógyszerkutatás alapját képezi. A kiválasztott biológiai célpont, leggyakrabban egy fehérje, működés
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f99f2405c55a5c6032aae811724f3daa
https://doi.org/10.1556/112.2021.00028
https://doi.org/10.1556/112.2021.00028
Autor:
I-Jen Chen, Proszenyák Ágnes, Zoltán B. Szabó, Levente Ondi, Csékei Márton, Olivier Geneste, Szabolcs Sipos, Allan E. Surgenor, Frédéric Colland, C. Pedder, Maïa Chanrion, Balázs Bálint, Ana-Leticia Maragno, Roderick E. Hubbard, Szlávik Zoltán, Pawel Dokurno, András Kotschy, James B. Murray, James R. Davidson
Publikováno v:
ACS Omega, Vol 6, Iss 34, Pp 22073-22102 (2021)
ACS Omega
ACS Omega
Following the identification of thieno[2,3-d]pyrimidine-based selective and potent inhibitors of MCL-1, we explored the effect of core swapping at different levels of advancement. During hit-to-lead optimization, X-ray-guided S-N replacement in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29a331e5552c24581a23a95aafbb773
https://doaj.org/article/8920fac56cd04386b0126955f672d5f2
https://doaj.org/article/8920fac56cd04386b0126955f672d5f2
Publikováno v:
Synthesis. 53:4313-4326
Hydrofluoroolefin (HFO) gases are state-of-the-art cooling agents with widespread household and industrial applications. Considering their structural benefits these fluorous feedstocks have gained the attention of organic chemists in the last couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1165d6369127f129d0475567b2e2c86c
https://doi.org/10.1055/a-1538-8344
https://doi.org/10.1055/a-1538-8344
Autor:
András Kotschy, Allan E. Surgenor, Andrea Fiumana, James Brooke Murray, Andrew Massey, Thomas Edmonds, Nicolas Foloppe, Didier Demarles, Pawel Dokurno, Mike Burbridge, Francisco Cruzalegui, K Benwell, Roderick E. Hubbard, Stuart C. Ray, Walmsley David, Julia Smith
Publikováno v:
Journal of Medicinal Chemistry. 64:8971-8991
The serine/threonine kinase DYRK1A has been implicated in regulation of a variety of cellular processes associated with cancer progression, including cell cycle control, DNA damage repair, protection from apoptosis, cell differentiation, and metastas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa669f3368474f2d06cdec15c347340
https://doi.org/10.1021/acs.jmedchem.1c00024
https://doi.org/10.1021/acs.jmedchem.1c00024