Zobrazeno 1 - 10
of 19
pro vyhledávání: '"András Dávid Tóth"'
Autor:
András Dávid Tóth, Eszter Soltész-Katona, Katalin Kis, Viktor Guti, Sharon Gilzer, Susanne Prokop, Roxána Boros, Ádám Misák, András Balla, Péter Várnai, Lilla Turiák, András Ács, László Drahos, Asuka Inoue, László Hunyady, Gábor Turu
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114241- (2024)
Summary: The binding and function of β-arrestins are regulated by specific phosphorylation motifs present in G protein-coupled receptors (GPCRs). However, the exact arrangement of phosphorylated amino acids responsible for establishing a stable inte
Externí odkaz:
https://doaj.org/article/d4a48bb17a7244b4b51ee21e0f338741
Autor:
Ádám Wiedemann, Virag Reka Szita, Róbert Horváth, Attila Sebő, András Dávid Tóth, Szabolcs Svorenj, Gergely Szombath, Tamas Masszi, Gergely Varga
Publikováno v:
HemaSphere, Vol 7, p e02903d8 (2023)
Externí odkaz:
https://doaj.org/article/5457f56348ae42bba0974f87bd057ad5
Autor:
Gergő Szanda, Tony Jourdan, Éva Wisniewski, Resat Cinar, Grzegorz Godlewski, Anikó Rajki, Jie Liu, Lee Chedester, Bence Szalai, András Dávid Tóth, Eszter Soltész-Katona, László Hunyady, Asuka Inoue, Viktória Bea Horváth, András Spät, Joseph Tam, George Kunos
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107207- (2023)
Summary: Molecular interactions between anorexigenic leptin and orexigenic endocannabinoids, although of great metabolic significance, are not well understood. We report here that hypothalamic STAT3 signaling in mice, initiated by physiological eleva
Externí odkaz:
https://doaj.org/article/fdec89d7da924457af4fc198282c561d
Autor:
Ádám Wiedemann, Virág Réka Szita, Róbert Horváth, Attila Szederjesi, Attila Sebő, András Dávid Tóth, Tamás Masszi, Gergely Varga
Publikováno v:
Pathology and Oncology Research, Vol 29 (2023)
Objective: Response to treatment in multiple myeloma (MM) is routinely measured by serum and urine M-protein and free light chain (FLC), as described by the International Myeloma Working Group (IMWG) consensus statement. A non-negligible subgroup of
Externí odkaz:
https://doaj.org/article/241b17c91ac8441cb0dd816073dab895
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
Autor:
Susanne Prokop, Péter Ábrányi-Balogh, Benjámin Barti, Márton Vámosi, Miklós Zöldi, László Barna, Gabriella M. Urbán, András Dávid Tóth, Barna Dudok, Attila Egyed, Hui Deng, Gian Marco Leggio, László Hunyady, Mario van der Stelt, György M. Keserű, István Katona
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The authors introduce PharmacoSTORM single-molecule imaging that uses fluorescent ligands and immunolabeling for cellular and subcellular nanoscale molecular pharmacology. They demonstrate its capabilities by visualizing cariprazine binding to D3 dop
Externí odkaz:
https://doaj.org/article/7fdcba0c8de84fc9bca36e38db68d9ba
Autor:
Kinga Bernadett Kovács, Laura Szalai, Pál Szabó, Janka Borbála Gém, Szilvia Barsi, Bence Szalai, Bernadett Perey-Simon, Gábor Turu, András Dávid Tóth, Péter Várnai, László Hunyady, András Balla
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3968 (2023)
Angiotensin II (AngII) is a vasoactive peptide hormone, which, under pathological conditions, contributes to the development of cardiovascular diseases. Oxysterols, including 25-hydroxycholesterol (25-HC), the product of cholesterol-25-hydroxylase (C
Externí odkaz:
https://doaj.org/article/4c2050e495a449d087f217f103c1d84f
Autor:
Laura Szalai, András Sziráki, László Sándor Erdélyi, Kinga Bernadett Kovács, Miklós Tóth, András Dávid Tóth, Gábor Turu, Dominique Bonnet, Bernard Mouillac, László Hunyady, András Balla
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The urine concentrating function of the kidney is essential to maintain the water homeostasis of the human body. It is mainly regulated by the arginine-vasopressin (AVP), which targets the type 2 vasopressin receptor (V2R) in the kidney. The inabilit
Externí odkaz:
https://doaj.org/article/36b00077d7ee4038ae353aba05ad8032
Autor:
Viktória B. Horváth, Eszter Soltész-Katona, Éva Wisniewski, Anikó Rajki, Eszter Halász, Balázs Enyedi, László Hunyady, András Dávid Tóth, Gergő Szanda
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The G protein-coupled type 1 cannabinoid receptor (CB1R) mediates virtually all classic cannabinoid effects, and both its agonists and antagonists hold major therapeutic potential. Heterologous expression of receptors is vital for pharmacological res
Externí odkaz:
https://doaj.org/article/64730e0b71c846e1940d57bc165d3272
Autor:
Gábor Turu, Eszter Soltész-Katona, András Dávid Tóth, Cintia Juhász, Miklós Cserző, Ádám Misák, András Balla, Marc G. Caron, László Hunyady
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
β-arrestins are partners of the G protein-coupled receptors (GPCRs), regulating their intracellular trafficking and signaling. Development of biased GPCR agonists, selectively targeting either G protein or β-arrestin pathways, are in the focus of i
Externí odkaz:
https://doaj.org/article/d831d60e1ce3493e8dd0908c6ec42da9
Autor:
Daniella Nagy, Katalin Révész, Gergely Peskó, Gergely Varga, Laura Horváth, Péter Farkas, András Dávid Tóth, Róbert Sepp, Hajnalka Vágó, Anikó Ilona Nagy, Tamás Masszi, Zoltán Pozsonyi
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1765 (2022)
Background: Cardiac amyloidosis (CA) is a rare, progressive, infiltrative cardiac disease. Light chain (AL) and transthyretin (ATTR) amyloidosis are in the background in almost all cases. New, easily available diagnostic tools and recently introduced
Externí odkaz:
https://doaj.org/article/d0a0aaac6355448b968d9a6be5f6c409