Zobrazeno 1 - 10
of 44
pro vyhledávání: '"András, Hrabák"'
Autor:
Gábor Bögel, József Murányi, Bálint Szokol, Zoltán Kukor, István Móra, Tamás Kardon, László Őrfi, András Hrabák
Publikováno v:
Heliyon, Vol 8, Iss 1, Pp e08670- (2022)
JAK/STAT pathway plays a well-known role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to identify new signaling pathways and repolarize macrophages by selected protein kinase inhibitors. HL-60
Externí odkaz:
https://doaj.org/article/8d69a1286fd64981bb1ef2a7c567d0de
Autor:
Zita Pánczél, Zoltán Kukor, Dorina Supák, Bence Kovács, András Kecskeméti, Rita Czizel, Magdolna Djurecz, Bálint Alasztics, Krisztián Benedek Csomó, András Hrabák, Sándor Valent
Publikováno v:
BMC Pregnancy and Childbirth, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Pravastatin, a known inducer of endothelial nitric-oxide synthase (eNOS) was demonstrated in human placenta, however the exact mechanism of it’s action is not fully understood. Since placental NO (nitric oxide) synthesis is of p
Externí odkaz:
https://doaj.org/article/c9af87c97fe14357aa9db4bda1eeb6ef
Autor:
András, Hrabák, Gábor, Bögel, József, Murányi, Viola, Tamási, Krisztina, Németh, Bálint, Szokol, Zoltán, Kukor, Tamás, Kardon, László, Őrfi
Publikováno v:
Molecular Immunology. 153:10-24
The JAK/STAT (Janus Kinase/Signal Transducer and Activator of Transcription) pathway plays a pivotal role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to reveal the relationship of activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e684199e2eb443102d23f33cd0a9cb5
https://doi.org/10.1016/j.molimm.2022.11.002
https://doi.org/10.1016/j.molimm.2022.11.002
Autor:
Krisztián Csomó, Andrea Belik, András Hrabák, Benedek Kovács, Orsolya Fábián, Sándor Valent, Gábor Varga, Zoltán Kukor
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 7; Pages: 1121
Statins are used to treat hypercholesterolemia, with several pleiotropic effects. Alongside their positive effects (for example, decreasing blood pressure), they can also bring about negative effects/symptoms (such as myopathy). Their main mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440986afc5643f8162be1fff70b2ff29
https://pubmed.ncbi.nlm.nih.gov/35887618
https://pubmed.ncbi.nlm.nih.gov/35887618
Autor:
Gábor Bögel, József Murányi, Bálint Szokol, Zoltán Kukor, István Móra, Tamás Kardon, László Őrfi, András Hrabák
Publikováno v:
Heliyon
Heliyon, Vol 8, Iss 1, Pp e08670-(2022)
Heliyon, Vol 8, Iss 1, Pp e08670-(2022)
JAK/STAT pathway plays a well-known role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to identify new signaling pathways and repolarize macrophages by selected protein kinase inhibitors. HL-60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea0cbbf215c2185a34881b010607024
https://pubmed.ncbi.nlm.nih.gov/35028455
https://pubmed.ncbi.nlm.nih.gov/35028455
Autor:
Istvan Marczell, Z. Kukor, Z. Tulassay, Attila Patocs, S. Toth, Gabor Nyiro, András Hrabák, Julia Stark, Gabor Bekesi, Elek Dinya, Kristóf Rácz
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 124(10)
Neutrophil granulocytes form the biggest free radical producing system of the human body. The importance of this system in atherosclerotic plaque formation and other free radical mediated disorders is confirmed by both in vivo and in vitro studies. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89f0cf774d3d1a9131bdb45ce7dc595
https://pubmed.ncbi.nlm.nih.gov/27437916
https://pubmed.ncbi.nlm.nih.gov/27437916
Publikováno v:
Inflammation Research. 60:1061-1070
The role of NO and adipocytokines in childhood obesity was studied, supposing that obesity provokes inflammation. Children were admitted to the pediatric clinic for a regular check up because of obesity. Obese (n = 79) and healthy (n = 12) children w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e981dbc9c7aa6dcb60f6a9b30683fd60
https://doi.org/10.1007/s00011-011-0367-9
https://doi.org/10.1007/s00011-011-0367-9
Publikováno v:
Amino Acids. 36:483-492
The uptake of L-arginine into mouse peritoneal macrophages can be inhibited by numerous amino acids and derivatives. Kinetic studies showed an almost entirely competitive inhibition for both cationic and neutral amino acids and derivatives suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3c90b3012294f87e046775c68a0949
https://doi.org/10.1007/s00726-008-0106-x
https://doi.org/10.1007/s00726-008-0106-x
Publikováno v:
Inflammation Research. 57:75-83
The effects of various inflammatory stimuli on the cytokine profile and phagocytic capacity of mouse and rat peritoneal macrophages were investigated in vitro. The correlations between cytokine concentrations and the expressions of NOS II and arginas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b080f95f47f3292f4491643104bbe0b
https://doi.org/10.1007/s00011-007-7057-7
https://doi.org/10.1007/s00011-007-7057-7
Publikováno v:
Amino Acids. 34:293-300
Numerous indolyl amino acids and their derivatives inhibited arginase activity. The inhibition was found to be non-competitive, - at least partly - allosteric, and independent on manganese ions in the active site, and it cannot be explained by the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c836228d95184dfc7e4d32004051f3b1
https://doi.org/10.1007/s00726-006-0470-3
https://doi.org/10.1007/s00726-006-0470-3