Zobrazeno 1 - 10
of 67
pro vyhledávání: '"András, Czurkó"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract During preclinical drug testing, the systemic administration of scopolamine (SCO), a cholinergic antagonist, is widely used. However, it suffers important limitations, like non-specific behavioural effects partly due to its peripheral side-e
Externí odkaz:
https://doaj.org/article/bc375befec4241b7a5e689a909becee5
Autor:
Gabriella Nyitrai, Tamás Spisák, Zsófia Spisák, Dávid Gajári, Pálma Diószegi, Tamás Zsigmond Kincses, András Czurkó
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198265 (2018)
Bilateral common carotid artery occlusion (BCCAo) in the rat is a widely used animal model of vascular dementia and a valuable tool for preclinical pharmacological drug testing, although the varying degrees of acute focal ischemic lesions it induces
Externí odkaz:
https://doaj.org/article/728564d32f1c445a837198d1243ac867
Autor:
Bence Farkas, Pálma Diószegi, Balázs Lendvai, Gabriella Nyitrai, András Czurkó, Ottilia Balázs, Bela Kiss
Publikováno v:
Journal of Psychopharmacology. 35:303-310
Background: Cariprazine is a dopamine D3-preferring D3/D2 receptor partial agonist compound recently introduced to treat schizophrenia and bipolar disorder. Although cariprazine is clinically classified as a low-somnolence drug, to date no detailed p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a02b2fe918c90b18622f8822d5f7ee
https://doi.org/10.1177/0269881120981378
https://doi.org/10.1177/0269881120981378
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Systemic administration of cholinergic antagonist scopolamine (SCO) is a widely used model to induce experimental cognitive impairment during preclinical drug testing of putative procognitive compounds. This model, however, has limited predictive val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7462b6c01b99a0934ec08611111ef19f
https://doi.org/10.1038/s41598-021-90273-9
https://doi.org/10.1038/s41598-021-90273-9
Autor:
Zsolt, Némethy, Béla, Kiss, Natasha, Lethbridge, Paul, Chazot, Tünde, Hajnik, Attila, Tóth, László, Détári, Éva, Schmidt, András, Czurkó, Diána, Kostyalik, Vilmos, Oláh, István, Hernádi, Ottilia, Balázs, E Sylvester, Vizi, István, Ledneczki, Sándor, Mahó, Viktor, Román, Balázs, Lendvai, György, Lévay
Publikováno v:
European journal of pharmacology. 916
The histamine H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d00db9c21eae4a299c02b5487aa1036b
https://pubmed.ncbi.nlm.nih.gov/34965389
https://pubmed.ncbi.nlm.nih.gov/34965389
Publikováno v:
Journal of Sleep Research. 30
N-methyl-d-aspartate receptors (NMDARs) play an important role in excitatory neurotransmission and have been associated with psychiatric conditions including schizophrenia and major depressive disorder. NMDARs are composed of two NR1 and two NR2 subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661db1955a73bfe0e52a78aacb942843
https://doi.org/10.1111/jsr.13257
https://doi.org/10.1111/jsr.13257
Efforts to advance translation through pre-clinical behavioural and pharmacological tests prompted attention to rat strain differences. Particularly the use of touchscreen technology for cognitive testing initiated the widespread use of Lister Hooded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3f87ada215b862825013c23f6190540
https://doi.org/10.1101/2020.12.03.409433
https://doi.org/10.1101/2020.12.03.409433
Autor:
F. Katalin Medzihradszky, Balazs Gyorffy, András Czurkó, Lilla Ravasz, Vilmos Tóth, Vanda Tukacs, Dávid Hlatky, Éva Hunyady-Gulyás, Katalin A. Kékesi, Gabriella Nyitrai, József Kardos, Dániel Mittli, Gábor Juhász
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
During chronic cerebral hypoperfusion (CCH), the cerebral blood flow gradually decreases, leading to cognitive impairments and neurodegenerative disorders, such as vascular dementia. The reduced oxygenation, energy supply induced metabolic changes, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c75d068998069811da2f56cbfde821f
https://doi.org/10.1038/s41598-020-72868-w
https://doi.org/10.1038/s41598-020-72868-w
Autor:
Zsolt Némethy, Béla Kiss, Natasha Lethbridge, Paul Chazot, Tünde Hajnik, Attila Tóth, László Détári, Éva Schmidt, András Czurkó, Diána Kostyalik, Vilmos Oláh, István Hernádi, Ottilia Balázs, E. Sylvester Vizi, István Ledneczki, Sándor Mahó, Viktor Román, Balázs Lendvai, György Lévay
Publikováno v:
European Journal of Pharmacology. 916:174621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1beae2435563c1ece7c1fadf0cc0b9b3
https://doi.org/10.1016/j.ejphar.2021.174621
https://doi.org/10.1016/j.ejphar.2021.174621
Autor:
Katalin Adrienna Kékesi, Gábor Juhász, Attila Simor, Péter Gulyássy, Eva Mónika Szegő, Eva Hunyadi-Gulyás, Zsuzsanna Darula, Katalin F Medzihradszky, Miklós Palkovits, Botond Penke, András Czurkó
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50532 (2012)
Probing molecular brain mechanisms related to increased suicide risk is an important issue in biological psychiatry research. Gene expression studies on post mortem brains indicate extensive changes prior to a successful suicide attempt; however, pro
Externí odkaz:
https://doaj.org/article/fd35c9e1423a408f957d1c6ab90a5e02