Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andie Collinson"'
Autor:
Christina Schindler, Andie Collinson, Carl Matthews, Amy Pointon, Lesley Jenkinson, Ralph R Minter, Tristan J Vaughan, Natalie J Tigue
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214545 (2019)
Doxorubicin is a chemotherapeutic agent that is commonly used to treat a broad range of cancers. However, significant cardiotoxicity, associated with prolonged exposure to doxorubicin, limits its continued therapeutic use. One strategy to prevent the
Externí odkaz:
https://doaj.org/article/d2a3717382b14d8298b565839ea17c6b
Autor:
Laura Fitzpatrick, Ralph Minter, Andie Collinson, Natalie J. Tigue, Tristan J. Vaughan, Carl Anthony Matthews, Michael Shaw, Lesley Jenkinson, Margaret Blundy, Andrea Longatti, Christina Schindler
Publikováno v:
Nanoscale. 10(29)
Exosomes are extracellular vesicles that mediate cell-to-cell communication by transferring biological cargo, such as DNA, RNA and proteins. Through genetic engineering of exosome-producing cells or manipulation of purified exosomes, it is possible t
Autor:
Maria A. Bednarek, Isabelle Sermadiras, David C. Hornigold, Jacqueline Naylor, Elise S.C. Bernard, Jacky Metcalfe, Andie Collinson
Publikováno v:
Proceedings of the 35th European Peptide Symposium.
Autor:
Julie Douthwaite, Jacques Moisan, Cyril Privezentzev, Blagoje Soskic, Shereen Sabbah, Suzanne Cohen, Andie Collinson, Elizabeth England, Catherine Huntington, Ben Kemp, Li Zhuang, Suzanne Hudak, D. Gareth Rees, Debbie Goldberg, Chris Barton, Linda Chang, Inna Vainshtein, Meina Liang, Laurie Iciek, Philip Ambery, Mark Peakman, Tristan J. Vaughan, Tim I. M. Tree, David M. Sansom, Michael A. Bowen, Ralph R. Minter, Lutz Jermutus
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(5)
Autor:
Evelyn Matthews, Siobhan O'Brien, Maria Fritsch-Fredin, Andie Collinson, Ronald Jackson, Monika Papworth, Lutz Jermutus, Markus G. Gruetter, Claire Priest, Peter Ravn, Lambertus Benthem, Susan Kunze, Chaithanya Madhurantakam
Publikováno v:
The Journal of Biological Chemistry
Background: GIPr mediates insulin secretion upon GIP stimulation. Results: Gipg013 is a highly specific and potent antagonist of GIPr with a fully characterized mode of action. Conclusion: Gipg013 antagonizes GIPr in vivo, as exemplified by inhibitio
Autor:
Tristan J. Vaughan, Linda Chang, Laurie Iciek, Timothy Tree, Philip Ambery, Elizabeth England, Inna Vainshtein, Debbie Goldberg, Catherine Huntington, Meina Liang, Suzanne Hudak, Suzanne Cohen, Chris Barton, Mark Peakman, Julie A. Douthwaite, Ben Kemp, Blagoje Soskic, Jacques Moisan, Li Zhuang, Ralph Minter, D. Gareth Rees, Andie Collinson, Shereen Sabbah, Michael A. Bowen, Lutz Jermutus, David M. Sansom, Cyril Privezentzev
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(1)
Affinity- and stability-engineered variants of CTLA4-Ig fusion molecules with enhanced pharmacokinetic profiles could yield improved therapies with the potential of higher efficacy and greater convenience to patients. In this study, to our knowledge,