Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Andiara E. Freitas"'
Autor:
Andiara E. Freitas, Bo Feng, Timothy Woo, Shae Galli, Clayton Baker, Yue Ban, Jonathan Truong, Anna Beyeler, Yimin Zou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Single administration of low-dose ketamine has both acute and sustained anti-depressant effects. Sustained effect is associated with restoration of glutamatergic synapses in medial prefrontal cortic (mFPC) neurons. Ketamine induced profound
Externí odkaz:
https://doaj.org/article/6171666aed9d46c4a1f77f8e71ed96e3
Autor:
Aneta Wojnicz, José Avendaño Ortiz, Ana I. Casas, Andiara E. Freitas, Manuela G. López, Ana Ruiz-Nuño
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 714-720 (2016)
The data presented in this article supports the rat brain sample preparation procedure previous to its injection into the liquid chromatography–tandem mass spectrometry (LC–MS/MS) system to monitor levels of adrenaline, noradrenaline, glutamic ac
Externí odkaz:
https://doaj.org/article/ecede8fbb410413eb1c2e1956caf5013
Publikováno v:
Developmental Dynamics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3deb3c2f34f8fbc9826e3ce282d7153d
https://doi.org/10.1002/dvdy.574
https://doi.org/10.1002/dvdy.574
Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling
Autor:
Yasmim de Oliveira Dalsenter, Morgana Moretti, Mauren K. Tavares, Priscila B. Rosa, Ana Lúcia S. Rodrigues, Daiane B. Fraga, Isabella A. Heinrich, Fernanda Neutzling Kaufmann, Luis E.B. Bettio, Vivian B. Neis, Andiara E. Freitas, Rodrigo B. Leal, Nicolle Platt, Isabel Werle, Axel Fogaça Rosado
Publikováno v:
Purinergic Signal
Guanosine is a purine nucleoside that has been shown to exhibit antidepressant effects, but the mechanisms underlying its effect are not well established. We investigated if the antidepressant-like effect induced by guanosine in the tail suspension t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260dfd9b576f53d13dbf3d65b85d5b61
https://doi.org/10.1007/s11302-021-09779-6
https://doi.org/10.1007/s11302-021-09779-6
Autor:
Roger Walz, Ana Lúcia S. Rodrigues, Rodrigo B. Leal, Ana Paula M. Nascimento, Isabella A. Heinrich, Andiara E. Freitas, Ingrid A.V. Wolin
Publikováno v:
Metabolic Brain Disease. 36:711-722
Fluoxetine is the foremost prescribed antidepressant. Drugs acting on monoaminergic system may also regulate glutamatergic system. Indeed, the investigation of proteins associated with this system, such as Narp (neuronal activity-dependent pentraxin)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968ce1b87b2ada433a4367940e034ab2
https://doi.org/10.1007/s11011-021-00675-x
https://doi.org/10.1007/s11011-021-00675-x
Autor:
Yimin Zou, Akumbir S. Grewal, Andiara E. Freitas, Bo Feng, Lilach Gorodetski, Yeo Rang Lee, Jingyi Wang, Runyi Tian
Publikováno v:
Science advances, vol 7, iss 34
Science Advances
Science Advances
Amyloid beta oligomers cause glutamatergic synapse degeneration by targeting the planar cell polarity components in the synapses.
The signaling pathway directly controlling the maintenance of adult glutamatergic synapses has not been well unders
The signaling pathway directly controlling the maintenance of adult glutamatergic synapses has not been well unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a46919abbb65573b23a97ed30b5def2
https://escholarship.org/uc/item/5kx8h77b
https://escholarship.org/uc/item/5kx8h77b
Autor:
Isabella A, Heinrich, Andiara E, Freitas, Ingrid A V, Wolin, Ana Paula M, Nascimento, Roger, Walz, Ana Lúcia S, Rodrigues, Rodrigo B, Leal
Publikováno v:
Metabolic brain disease. 36(4)
Fluoxetine is the foremost prescribed antidepressant. Drugs acting on monoaminergic system may also regulate glutamatergic system. Indeed, the investigation of proteins associated with this system, such as Narp (neuronal activity-dependent pentraxin)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eaf4ae7b358b4fd64019ca800224e87e
https://pubmed.ncbi.nlm.nih.gov/33528752
https://pubmed.ncbi.nlm.nih.gov/33528752
Autor:
Runyi Tian, Yimin Zou, Bo Feng, Akumbir S. Grewal, Yeo Rang Lee, Jingyi Wang, Andiara E. Freitas
Synapse loss is an early event in Alzheimer’s disease and is thought to be associated with amyloid pathology and caused by Amyloid β (Aβ) oligomers. Whether and how Aβ oligomers directly target signaling pathways for glutamatergic synapse mainte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4cb016b8b99f136d8c0f75ddc3a512
https://doi.org/10.1101/2020.09.09.273011
https://doi.org/10.1101/2020.09.09.273011
Autor:
Isabella A. Heinrich, Andiara E. Freitas, Mauren K. Tavares, Manuella P. Kaster, Ingrid A.V. Wolin, Rodrigo B. Leal, Suellen dos Reis, Ana Lúcia S. Rodrigues, Nicolle Platt
Publikováno v:
Neurochemistry International. 118:275-285
Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is one of the most robust neurobiological findings in the pathophysiology of major depressive disorder (MDD) over the last 40 years. The persistent increase in glucocorticoids levels indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d49b3c875117599218163a6e36020c
https://doi.org/10.1016/j.neuint.2018.05.006
https://doi.org/10.1016/j.neuint.2018.05.006
Autor:
Andiara E. Freitas, Josiane Budni, Camille M. Ribeiro, Rodrigo B. Leal, Ana Lúcia S. Rodrigues, Débora Kurrle Rieger, Grasiela O. Balen, Vivian B. Neis, Morgana Moretti
Publikováno v:
Behavioural Brain Research. 414:113512
Folic acid has been reported to exert antidepressant effects, but its ability to abrogate the depressive-like behavior and signaling pathways alterations elicited by an inflammatory model of depression remains to be established. This study examined:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bfef2f339f31bab054fab36d7f0d35
https://doi.org/10.1016/j.bbr.2021.113512
https://doi.org/10.1016/j.bbr.2021.113512