Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Andia N Redpath"'
Autor:
Andia N. Redpath, Nicola Smart
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 4, Pp 511-521 (2021)
Abstract Research into potential targets for cardiac repair encompasses recognition of tissue‐resident cells with intrinsic regenerative properties. The adult vertebrate heart is covered by mesothelium, named the epicardium, which becomes active in
Externí odkaz:
https://doaj.org/article/03b3c9f267c14777a1da6311d79e274a
Autor:
Jacinta I. Kalisch-Smith, Emily C. Morris, Mary A. A. Strevens, Andia N. Redpath, Kostantinos Klaourakis, Dorota Szumska, Jennifer E. Outhwaite, Xin Sun, Joaquim Miguel Vieira, Nicola Smart, Sarah De Val, Paul R. Riley, Duncan B. Sparrow
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
The placental vasculature provides the developing embryo with a circulation to deliver nutrients and dispose of waste products. However, in the mouse, the vascular components of the chorio-allantoic placenta have been largely unexplored due to a lack
Externí odkaz:
https://doaj.org/article/65a5a2d0d0f643d38839c84a26d650f5
Autor:
Sophie Payne, Mala Gunadasa-Rohling, Alice Neal, Andia N. Redpath, Jyoti Patel, Kira M. Chouliaras, Indrika Ratnayaka, Nicola Smart, Sarah De Val
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
How coronary vessels develop and respond to injury is not fully understood. Here, the authors use murine enhancer:reporter models to identify three transcriptional pathways active in different parts of coronary vasculature. These also contribute to n
Externí odkaz:
https://doaj.org/article/09fd5481e99346098921b08317905204
Publikováno v:
Blood Advances, Vol 1, Iss 22, Pp 1934-1943 (2017)
Abstract: Pharmacological mobilization of hematopoietic progenitor cells (HPCs) is used clinically to harvest HPCs for bone marrow transplants. It is now widely accepted that the CXCR4:CXCL12 chemokine axis plays a critical role in the retention of H
Externí odkaz:
https://doaj.org/article/5e532f57c7814c2c8eeec117d7668c4a
ObjectiveAtherosclerosis is a progressive, degenerative vascular disease and a leading cause of morbidity and mortality. In response to endothelial damage, platelet derived growth factor (PDGF)-BB induced phenotypic modulation of medial smooth muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1f803ac3e5a8ef973609f974937fc2
https://doi.org/10.1101/2021.11.30.470548
https://doi.org/10.1101/2021.11.30.470548
The epicardium is a fundamental regulator of cardiac development, functioning to secrete essential growth factors and to produce epicardium-derived cells (EPDCs) that contribute most coronary vascular smooth muscle cells and cardiac fibroblasts. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbc7478565697244d2d1886d1249e08b
https://doi.org/10.1101/2021.11.25.470003
https://doi.org/10.1101/2021.11.25.470003
Autor:
Nicola Smart, Dorota Szumska, Jacinta I. Kalisch-Smith, Joaquim M. Vieira, Morris Ec, Andia N. Redpath, J.E. Outhwaite, De Val S, Konstantinos Klaourakis, Paul R. Riley, Strevens Ma, Duncan B. Sparrow
Placental vascular gene networks in mammals have been largely unexplored due to a lack of well validated molecular markers to identify them. This is required to study how they form in development, and how they are impacted by embryonic or maternal de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c02258c8fd11696fc8608cc956df3d
https://doi.org/10.1101/2021.05.06.442902
https://doi.org/10.1101/2021.05.06.442902
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100359-(2021)
STAR Protocols
STAR Protocols
Summary Genetic markers used to define discrete cell populations are seldom expressed exclusively in the population of interest and are, thus, unsuitable when evaluated individually, especially in the absence of spatial and morphological information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2862584444050c1bea8828e7543072
http://www.sciencedirect.com/science/article/pii/S2666166721000666
http://www.sciencedirect.com/science/article/pii/S2666166721000666
Autor:
Sonali Munshaw, Giles Neal, Karina N. Dubé, Susann Bruche, Jyoti Patel, Nicola Smart, Rachel Davies, Regent Lee, Ashok Handa, Andia N. Redpath, Keith M. Channon
Background and Aims: Thymosin β4 (Tβ4), is a small peptide implicated in mural VSMC differentiation in developing embryo. A proportion of Tβ4KO embryos die with vascular haemorrhage and surviving adults display aortic VSMC and elastin defects. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3696e8f88303fea2ee5e7d65e414c039
https://ora.ox.ac.uk/objects/uuid:e3241180-db55-4a6c-9779-978f44591f92
https://ora.ox.ac.uk/objects/uuid:e3241180-db55-4a6c-9779-978f44591f92
Autor:
Julian R. Jones, Olga Tsigkou, Mary P. Ryan, Samuel J. Page, Shu Chen, John V. Hanna, Sara M. Rankin, Parichart Naruphontjirakul, Zhan Yuin Ong, Andia N. Redpath, Alexandra E. Porter, Sarah L. Greasley
Publikováno v:
Materials Today Advances, Vol 6, Iss, Pp-(2020)
Triple-negative breast cancers are extremely aggressive with limited treatment options because of the reduced response of the cancerous cells to hormonal therapy. Here, monodispersed zinc-containing mesoporous silica nanoparticles (MSNPs-Zn) were pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8b933b555b30228e9702c597cc05b9
http://hdl.handle.net/10044/1/80666
http://hdl.handle.net/10044/1/80666