Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Andi, Wangzhou"'
Autor:
Mayur Patil, Sergei Belugin, Jennifer Mecklenburg, Andi Wangzhou, Candler Paige, Priscilla A. Barba-Escobedo, Jacob T. Boyd, Vincent Goffin, David Grattan, Ulrich Boehm, Gregory Dussor, Theodore J. Price, Armen N. Akopian
Publikováno v:
iScience, Vol 20, Iss , Pp 449-465 (2019)
Summary: Many clinical and preclinical studies report an increased prevalence and severity of chronic pain among females. Here, we identify a sex-hormone-controlled target and mechanism that regulates dimorphic pain responses. Prolactin (PRL), which
Externí odkaz:
https://doaj.org/article/480a911199dc475b90157a763911ad44
Autor:
Pradipta R. Ray, Jawad Khan, Andi Wangzhou, Diana Tavares-Ferreira, Armen N. Akopian, Gregory Dussor, Theodore J. Price
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Sex differences in gene expression are important contributors to normal physiology and mechanisms of disease. This is increasingly apparent in understanding and potentially treating chronic pain where molecular mechanisms driving sex differences in n
Externí odkaz:
https://doaj.org/article/8bcbf372fa754264be65d107aa23680c
Autor:
Armen N. Akopian, Paulino Barragán-Iglesias, Andi Wangzhou, Galo L. Mejia, Stephanie Shiers, Diana Tavares-Ferreira, Salim Megat, Ishwarya Sankaranarayanan, Gregory Dussor, Ruta Uttarkar, Pradipta R. Ray, Theodore J. Price
Publikováno v:
Biol Psychiatry
BackgroundThere are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2625e101051fb502a769fc1ad537918
https://doi.org/10.1016/j.biopsych.2020.09.022
https://doi.org/10.1016/j.biopsych.2020.09.022
Autor:
Amelia J. McFarland, Pradipta R. Ray, Steve Davidson, Muhammad Saad Yousuf, Gregory Dussor, Sanjay V. Neerukonda, Candler Paige, Michael D. Burton, Stephanie Shiers, Ishwarya Sankaranarayanan, Andi Wangzhou, Juliet Mwirigi, Nizar Ghneim, Diana Tavares-Ferreira, Theodore J. Price
Publikováno v:
Brain, Behavior, and Immunity
SSRN
SSRN
Highlights • Our paper identifies key neuro-immune interactions in the lungs of COVID-19 patients that potentially drive neurogenic pulmonary dysfunction. • Our framework uses an interactome prediction model to identify relevant ligand – recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0a639a79230c4bdf69e2af990d4ec4
https://doi.org/10.1016/j.bbi.2020.05.078
https://doi.org/10.1016/j.bbi.2020.05.078
Autor:
Yi Zou, Zhao Lai, Dawn Garcia, Theodore J. Price, Jennifer Mecklenburg, Gregory Dussor, Armen N. Akopian, Alexei V. Tumanov, Andi Wangzhou
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
Many chronic pain conditions show sex differences in their epidemiology. This could be attributed to sex-dependent differential expression of genes (DEGs) involved in nociceptive pathways, including sensory neurons. This study aimed to identify sex-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f44114aac0a928be00d5267c667c3c9
http://link.springer.com/article/10.1038/s41598-020-72285-z
http://link.springer.com/article/10.1038/s41598-020-72285-z
Autor:
Pradipta R. Ray, Megan L. Uhelski, Ishwarya Sankaranarayanan, Theodore J. Price, Stephanie Shiers, Yan Li, Andi Wangzhou, Patrick M. Dougherty, Claudio E. Tatsui, Laurence D. Rhines
Publikováno v:
Pain
SARS-CoV-2 has created a global crisis. COVID-19, the disease caused by the virus, is characterized by pneumonia, respiratory distress, and hypercoagulation and can be fatal. An early sign of infection is loss of smell, taste, and chemesthesis-loss o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8617e59baa061da9f064891a71426254
https://doi.org/10.1097/j.pain.0000000000002051
https://doi.org/10.1097/j.pain.0000000000002051
Autor:
Paulino Barragán-Iglesias, Gregory Dussor, Carolyn A. Guzman, Stephanie Shiers, Candler Paige, Andi Wangzhou, Pradipta R. Ray, Robert W. Gereau, Lisa A. McIlvried, Ayesha Ahmad, Theodore J. Price
Publikováno v:
Pain
Dorsal root ganglion (DRG) neurons detect sensory inputs and are crucial for pain processing. They are often studied in vitro as dissociated cell cultures with the assumption that this reasonably represents in vivo conditions. However, to the best of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe39e5514d6d8e7a5c242158935bc443
https://doi.org/10.1097/j.pain.0000000000001866
https://doi.org/10.1097/j.pain.0000000000001866
Autor:
Diana Tavares-Ferreira, Stephanie Shiers, Pradipta R. Ray, Andi Wangzhou, Vivekanand Jeevakumar, Ishwarya Sankaranarayanan, Anna M. Cervantes, Jeffrey C. Reese, Alexander Chamessian, Bryan A. Copits, Patrick M. Dougherty, Robert W. Gereau, Michael D. Burton, Gregory Dussor, Theodore J. Price
Publikováno v:
Sci Transl Med
Nociceptors are specialized sensory neurons that detect damaging or potentially damaging stimuli and are found in the dorsal root ganglia (DRG) and trigeminal ganglia. These neurons are critical for the generation of neuronal signals that ultimately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f376ed3fdb7b9919041ec8b303c00a
https://doi.org/10.1126/scitranslmed.abj8186
https://doi.org/10.1126/scitranslmed.abj8186
Autor:
Jennifer Mecklenburg, Andi Wangzhou, Anahit H. Hovhannisyan, Priscilla Barba-Escobedo, Sergey A. Shein, Yi Zou, Korri Weldon, Zhao Lai, Vincent Goffin, Gregory Dussor, Alexei V. Tumanov, Theodore J. Price, Armen N. Akopian
Publikováno v:
Brain Behav Immun
Pain development and resolution patterns in many diseases are sex-dependent. This study aimed to develop pain models with sex-dependent resolution trajectories, and identify factors linked to resolution of pain in females and males. Using different i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81383341a1e0cdc8202d491fc8243ddb
https://europepmc.org/articles/PMC9173405/
https://europepmc.org/articles/PMC9173405/
Autor:
Armen N. Akopian, David R. Grattan, Gregory Dussor, Andi Wangzhou, Jennifer Mecklenburg, Theodore J. Price, Candler Paige, Jacob T. Boyd, Vincent Goffin, Mayur J. Patil, Sergei Belugin, Priscilla A. Barba-Escobedo, Ulrich Boehm
Publikováno v:
iScience
iScience, Vol 20, Iss, Pp 449-465 (2019)
iScience, Vol 20, Iss, Pp 449-465 (2019)
Summary Many clinical and preclinical studies report an increased prevalence and severity of chronic pain among females. Here, we identify a sex-hormone-controlled target and mechanism that regulates dimorphic pain responses. Prolactin (PRL), which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87da21d184792aa1d64e54b53f2650e0
https://doi.org/10.1016/j.isci.2019.09.039
https://doi.org/10.1016/j.isci.2019.09.039