Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Andhyk Halim"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Many biopharmaceuticals exhibit mixed heterogeneity in their post-translational modifications (PTMs) that are essential for their function. Here the authors use a combination of mass spectrometry techniques to analyse human erythropoietin (EPO) and p
Externí odkaz:
https://doaj.org/article/b02ee70614ff4f99a5c217410f8e376c
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Many biopharmaceutical products exhibit extensive structural micro-heterogeneity due to an array of co-occurring post-translational modifications. These modifications often effect the functionality of the product and therefore need to be characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f90dd4d4e98f03dc342a98b8953b7f4
https://pubmed.ncbi.nlm.nih.gov/27824045
https://pubmed.ncbi.nlm.nih.gov/27824045
Publikováno v:
mAbs. 4:740-752
The presence of protein aggregates in biopharmaceutical formulations is of great concern for safety and efficacy reasons. The aim of this study was to correlate the type and amount of IgG monoclonal antibody aggregates with their immunogenic potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c18610844b2f278cd9dc010ed8bb827
https://doi.org/10.4161/mabs.22066
https://doi.org/10.4161/mabs.22066