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pro vyhledávání: '"Anderson V Brian"'
Autor:
Anderson V Brian, Howard B. Lassman, Richard C. Allen, J. C. Wilker, William J. Novick, Marc N. Agnew
Publikováno v:
Journal of Medicinal Chemistry. 19:318-325
An extensive series of carboxyarylindoles has been evaluated for antiinflammatory activity in the carrageenin paw edema assay. The requirements for optimal antiinflammatory activity in this series are relatively specific: a central pyrrole nucleus wi
Autor:
Helen H. Ong, Hansjoerg Kruse, Harry M. Geyer, James A. Profitt, Anderson V Brian, J. C. Wilker
Publikováno v:
Journal of Medicinal Chemistry. 24:74-79
A series of 3-aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidine] derivatives was synthesized and evaluated pharmacologically for potential psychotropic activity. Potent antidepressant-like activity was noted throughout the series, as assessed b