Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anderson P. Kanagaraj"'
Autor:
Baochang Fan, Yimei Li, Brett J. Winborn, J. Paul Taylor, Emmanuelle R. Quemin, Jennifer Moore, Rebecca B. Smith, Helen C. Miranda, Burgess B. Freeman, Jennifer Dearman, Ane Korff, Hong Joo Kim, Pradeep K. Vuppala, Heather Tillman, James Messing, Brian D. Freibaum, Ping-Chung Chen, Albert R. La Spada, Nam Chul Kim, Anderson P. Kanagaraj, Bryce L. Sopher, Yingzhe Wang, Nisha M. Badders
Publikováno v:
Nature Medicine. 24:427-437
Spinal bulbar muscular atrophy (SBMA) is a motor neuron disease caused by toxic gain of function of the androgen receptor (AR). Previously, we found that co-regulator binding through the activation function-2 (AF2) domain of AR is essential for patho
Autor:
J. Paul Taylor, Ichiro Yabe, Eric D. Ross, Mishie Tanino, Songqing Li, Hidenao Sasaki, Shinya Tanaka, Regina-Maria Kolaitis, Brian D. Freibaum, Hong Joo Kim, Anderson P. Kanagaraj, Peipei Zhang, Nam Chul Kim, Amandine Molliex
Publikováno v:
Human Molecular Genetics. 25:936-950
Adult-onset inherited myopathies with similar pathological features, including hereditary inclusion body myopathy (hIBM) and limb-girdle muscular dystrophy (LGMD), are a genetically heterogeneous group of muscle diseases. It is unclear whether these
Autor:
Alison J. Clare, Rebecca B. Smith, Siddharthan Chandran, J. Paul Taylor, Luis A. Williams, Christopher Shaw, Steve S.W. Han, Brian D. Freibaum, Nisha M. Badders, Brett J. Winborn, Kevin Eggan, Tom Maniatis, Anderson P. Kanagaraj, Monica A. Carrasco, Evangelos Kiskinis, Edward Chaum, Christina S. Winborn, Nael H. Alami, Bilada Bilican
Publikováno v:
Neuron. 81:536-543
SummaryThe RNA-binding protein TDP-43 regulates RNA metabolism at multiple levels, including transcription, RNA splicing, and mRNA stability. TDP-43 is a major component of the cytoplasmic inclusions characteristic of amyotrophic lateral sclerosis an
Autor:
David Finkelstein, Matthew Parker, Jinghui Zhang, Richard J. Gilbertson, Hong Joo Kim, Anderson P. Kanagaraj, Yong-Dong Wang, Deanna M. Patmore, Jennifer Moore, David W. Ellison, J. Paul Taylor, Michael Rusch, Yasmine A. Valentin-Vega
Publikováno v:
Scientific Reports
DDX3X is a DEAD-box RNA helicase that has been implicated in multiple aspects of RNA metabolism including translation initiation and the assembly of stress granules (SGs). Recent genomic studies have reported recurrent DDX3X mutations in numerous tum
Autor:
J. Paul Taylor, Hong Joo Kim, Maura Coughlin, Tanja Mittag, Amandine Molliex, Jamshid Temirov, Anderson P. Kanagaraj, Jihun Lee
SummaryStress granules are membrane-less organelles composed of RNA-binding proteins (RBPs) and RNA. Functional impairment of stress granules has been implicated in amyotrophic lateral sclerosis, frontotemporal dementia, and multisystem proteinopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134bf4c534d4dff7662308c7c7a4cc8e
https://europepmc.org/articles/PMC5149108/
https://europepmc.org/articles/PMC5149108/