Zobrazeno 1 - 10 of 222 pro vyhledávání: '"Andersen Claus L"'
3
Akademický článek
Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis
Autor: Laurila Kirsti, Mansilla Francisco, Eller Asger, Pedersen Jakob, Lamy Philippe, Hansen Kristian Q, Wang Kai, Vang Søren, Rasmussen Mads H, Øster Bodil, Schepeler Troels, Thorsen Kasper, Wiuf Carsten, Laurberg Søren, Dyrskjøt Lars, Ørntoft Torben F, Andersen Claus L
Publikováno v: BMC Genomics, Vol 12, Iss 1, p 505 (2011)
Abstract Background Approximately half of all human genes use alternative transcription start sites (TSSs) to control mRNA levels and broaden the transcriptional output in healthy tissues. Aberrant expression patterns promoting carcinogenesis, howeve
Externí odkaz: https://doaj.org/article/b06ffd3760064e718d4cabbb00ff11b6
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4
Akademický článek
Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs
Autor: Ørntoft Torben F, Dyrskjøt Lars, Ostenfeld Marie S, Rasmussen Mads H, Lamy Philippe, Jensen Steffen G, Andersen Claus L
Publikováno v: BMC Genomics, Vol 12, Iss 1, p 435 (2011)
Abstract Background microRNAs (miRNA) are short, endogenous transcripts that negatively regulate the expression of specific mRNA targets. miRNAs are found both in tissues and body fluids such as plasma. A major perspective for the use of miRNAs in th
Externí odkaz: https://doaj.org/article/c13238609de54c6ca83a9674e5cf323c
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5
Akademický článek
A Beta-mixture model for dimensionality reduction, sample classification and analysis
Autor: Orntoft Torben, Lamy Philippe, Andersen Claus L, Oster Bodil, Laurila Kirsti, Yli-Harja Olli, Wiuf Carsten
Publikováno v: BMC Bioinformatics, Vol 12, Iss 1, p 215 (2011)
Abstract Background Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper we propose a beta-mixture model to describe genome-wide methyla
Externí odkaz: https://doaj.org/article/df55ebe811c049d3a1e91cb5e56b003b
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6
Akademický článek
The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population
Autor: Syvänen Ann-Christine, Olsen Anja, Tjønneland Anne, Koed Karen, Wiuf Carsten, Wikman Friedrik P, Madsen Bo E, Christensen Lise, Andersen Claus L, Ørntoft Torben F
Publikováno v: BMC Medical Genetics, Vol 9, Iss 1, p 52 (2008)
Abstract Background Mutations in the mismatch repair genes hMLH1 and hMSH2 predispose to hereditary non-polyposis colorectal cancer (HNPCC). Genetic screening of more than 350 Danish patients with colorectal cancer (CRC) has led to the identification
Externí odkaz: https://doaj.org/article/b1546d9cc8e542579b4be71aec4aa841
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7
Akademický článek
A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays
Autor: Torring Niels, Dyrskjot Lars, Andersen Claus L, Lamy Philippe, Wiuf Carsten
Publikováno v: BMC Bioinformatics, Vol 8, Iss 1, p 434 (2007)
Abstract Background Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlying events leading to cancer. Genomic copy-numbers are today rou
Externí odkaz: https://doaj.org/article/8c055ae3fbf34982a08cb9f42e218df9
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8
Akademický článek
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