Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Anders Sundan"'
Autor:
Ingrid Quist-Løkken, Clara Andersson-Rusch, Martin Haugrud Kastnes, Jürgen Markus Kolos, Jerome Jatzlau, Hanne Hella, Oddrun Elise Olsen, Anders Sundan, Petra Knaus, Felix Hausch, Toril Holien
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background The immunophilin FKBP12 binds to TGF-β family type I receptors, including the BMP type I receptor ALK2. FKBP12 keeps the type I receptor in an inactive state and controls signaling activity. Removal of FKBP12 with drugs such as t
Externí odkaz:
https://doaj.org/article/1d7144747e7f4e01a14dd611f82ff44b
Autor:
Kristin Roseth Aass, Robin Mjelle, Martin H. Kastnes, Synne S. Tryggestad, Luca M. van den Brink, Ingrid Aass Roseth, Marita Westhrin, Muhammad Zahoor, Siv H. Moen, Tonje M. Vikene Nedal, Glenn Buene, Kristine Misund, Anne-Marit Sponaas, Qianli Ma, Anders Sundan, Richard WJ. Groen, Tobias S. Slørdahl, Anders Waage, Therese Standal
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103605- (2022)
Summary: Interleukin-32 (IL-32) is a nonclassical cytokine expressed in cancers, inflammatory diseases, and infections. Its expression is regulated by two different oxygen sensing systems; HIF1α and cysteamine dioxygenase (ADO), indicating that IL-3
Externí odkaz:
https://doaj.org/article/f13877db61e44076b7c17265f09790b3
Autor:
Anne Marit Sponaas, Anders Waage, Esten N. Vandsemb, Kristine Misund, Magne Børset, Anders Sundan, Tobias Schmidt Slørdahl, Therese Standal
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In this review article we discuss the role of the memory T cells in multiple myeloma (MM) and how they may influence immune responses in patients that received immunomodulating drugs and check point therapy.
Externí odkaz:
https://doaj.org/article/b18d1d6eff314e62be1a314571453916
Autor:
Samah Elsaadi, Kristine Misund, Pegah Abdollahi, Esten Nymoen Vandsemb, Siv Helen Moen, Anna Kusnierczyk, Geir Slupphaug, Therese Standal, Anders Waage, Tobias S Slørdahl, Even Rustad, Anders Sundan, Carl Hay, Alwin G Schuller, Alexandra Borodovsky, Eline Menu, Magne Børset, Anne Marit Sponaas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background PD1/PDL1-directed therapies have been unsuccessful for multiple myeloma (MM), an incurable cancer of plasma cells in the bone marrow (BM). Therefore, other immune checkpoints such as extracellular adenosine and its immunosuppressive recept
Externí odkaz:
https://doaj.org/article/0d6878b13bc74341af00666681fe9034
Autor:
Samah Elsaadi, Kristine Misund, Pegah Abdollahi, Esten Nymoen Vandsemb, Siv Helen Moen, Anna Kusnierczyk, Geir Slupphaug, Therese Standal, Anders Waage, Tobias S Slørdahl, Even Rustad, Anders Sundan, Carl Hay, Alwin G Schuller, Alexandra Borodovsky, Eline Menu, Magne Børset, Anne Marit Sponaas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/f20fcca431404e1194b00e73ffb1a28d
Autor:
Marita Westhrin, Toril Holien, Muhammad Zahoor, Siv Helen Moen, Glenn Buene, Berit Størdal, Hanne Hella, Huipin Yuan, Joost D deBruijn, Anton Martens, Richard WJ Groen, Fatima Bosch, Ulf Smith, Anne‐Marit Sponaas, Anders Sundan, Therese Standal
Publikováno v:
JBMR Plus, Vol 4, Iss 1, Pp n/a-n/a (2020)
ABSTRACT Multiple myeloma is characterized by accumulation of malignant plasma cells in the bone marrow. Most patients suffer from an osteolytic bone disease, caused by increased bone degradation and reduced bone formation. Bone morphogenetic protein
Externí odkaz:
https://doaj.org/article/bf762c5de17d4765a176670e3c83276e
Autor:
Thea Kristin Våtsveen, Marit Renée Myhre, Chloé Beate Steen, Sébastien Wälchli, Ole Christian Lingjærde, Baoyan Bai, Pierre Dillard, Theodossis A. Theodossiou, Toril Holien, Anders Sundan, Else Marit Inderberg, Erlend B. Smeland, June Helen Myklebust, Morten P. Oksvold
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background Although chemo-immunotherapy has led to an improved overall survival for most B-cell lymphoma types, relapsed and refractory disease remains a challenge. The malaria drug artesunate has previously been identified as a growth suppr
Externí odkaz:
https://doaj.org/article/f1427b199c214b4aa939a876ff172b33
Autor:
Muhammad Zahoor, Marita Westhrin, Kristin Roseth Aass, Siv Helen Moen, Kristine Misund, Katarzyna Maria Psonka-Antonczyk, Mariaserena Giliberto, Glenn Buene, Anders Sundan, Anders Waage, Anne-Marit Sponaas, Therese Standal
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2656-2666 (2017)
Abstract: Multiple myeloma (MM) is a hematologic cancer characterized by expansion of malignant plasma cells in the bone marrow. Most patients develop an osteolytic bone disease, largely caused by increased osteoclastogenesis. The myeloma bone marrow
Externí odkaz:
https://doaj.org/article/d8b05d66de814a69b4cc46a1e04fb50d
Autor:
Thea Kristin Våtsveen, Anne-Marit Sponaas, Erming Tian, Qing Zhang, Kristine Misund, Anders Sundan, Magne Børset, Anders Waage, Gaute Brede
Publikováno v:
Journal of Hematology & Oncology, Vol 9, Iss 1, Pp 1-9 (2016)
Abstract Background Multiple myeloma is an incurable complex disease characterized by clonal proliferation of malignant plasma cells in a hypoxic bone marrow environment. Hypoxia-dependent erythropoietin (EPO)-receptor (EPOR) signaling is central in
Externí odkaz:
https://doaj.org/article/c1d37908ecac46e5a181d4fb359c5a20
Autor:
Even Holth Rustad, Eivind Coward, Emilie R Skytøen, Kristine Misund, Toril Holien, Therese Standal, Magne Børset, Vidar Beisvag, Ola Myklebost, Leonardo A Meza-Zepeda, Hong Yan Dai, Anders Sundan, Anders Waage
Publikováno v:
Haematologica, Vol 102, Iss 7 (2017)
Circulating tumor DNA is a promising biomarker to monitor tumor load and genome alterations. We explored the presence of circulating tumor DNA in multiple myeloma patients and its relation to disease activity during long-term follow-up. We used digit
Externí odkaz:
https://doaj.org/article/bab1815a0a18458295235e2d02264508