Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Anders Rudehill"'
Publikováno v:
Critical Care Medicine. 34:1437-1443
Objectives To compare the single thermal indicator dilution (STID) technique for measurement of extravascular lung water (EVLW(STID)) with gravimetrically determined EVLW (EVLW(GRAV)) in anesthetized pigs under sham and endotoxemic conditions. Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5382dd0e83c9059f64e0d652145d54be
https://doi.org/10.1097/01.ccm.0000215830.48977.29
https://doi.org/10.1097/01.ccm.0000215830.48977.29
Publikováno v:
Critical Care Medicine. 32:1192-1199
Objective: To evaluate the effects of endothelin receptor antagonism on cardiac performance in endotoxin shock. Design: Prospective, experimental study. Setting: A university-affiliated research institution. Subjects: Domestic anesthetized landrace p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90007467248a83fe4a22a4e6e9ab6f0f
https://doi.org/10.1097/01.ccm.0000126262.23422.f0
https://doi.org/10.1097/01.ccm.0000126262.23422.f0
Publikováno v:
Acta Anaesthesiologica Scandinavica. 45:1262-1270
Background: Cardiac dysfunction during septic shock is well described but the underlying mechanisms still remain to be resolved. This study was conducted to elucidate the involvement of endothelin in cardiac function during endotoxin shock by the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1bc6fd30b1a3be194ef46c524bbf012
https://doi.org/10.1034/j.1399-6576.2001.451015.x
https://doi.org/10.1034/j.1399-6576.2001.451015.x
Autor:
Anders Oldner, Kjell Alving, Eddie Weitzberg, Anders Rudehill, Pierre Sundin, Michael Wanecek
Publikováno v:
Karolinska Institutet
The endothelin system is highly activated during endotoxin and septic shock. To investigate this matter the selective non-peptide endothelin ET(B) receptor antagonist A-192621 ([2R-(2alpha,3beta, 4alpha)]-4-(1,3-benzodioxol-5-yl)-1-[2-[2, 6-diethylph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37753277a58be41f51f3ec89f3b428e3
https://doi.org/10.1016/s0014-2999(99)00774-8
https://doi.org/10.1016/s0014-2999(99)00774-8
Autor:
Anders Oldner, Pierre Sundin, Eddie Weitzberg, Per M. Hellström, Alf Sollevi, Anders Rudehill, Kjell Alving, Michael Wanecek, Carlos A. Rubio
Publikováno v:
British Journal of Pharmacology. 127:1793-1804
1. The non-selective endothelin (ET) receptor antagonist bosentan has been shown to restore systemic and gut oxygen delivery and reverse intestinal mucosal acidosis in porcine endotoxin shock. 2. To further elucidate the specific role of the ETA as o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a8b6cde558fc05d5f97596064702078
https://doi.org/10.1038/sj.bjp.0702736
https://doi.org/10.1038/sj.bjp.0702736
Autor:
Anders Oldner, Kjell Alving, Anders Rudehill, Eddie Weitzberg, Michael Wanecek, Johan Ullman, Mats Rundgren
Publikováno v:
Karolinska Institutet
Europe PubMed Central
Europe PubMed Central
The renin angiotensin system is highly activated in shock states and has been suggested to be involved in the pathophysiology of the markedly deteriorated splanchnic circulation seen in septic shock. The purpose of the present study was to elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91ade70613c0929a5fc71fe3b45138f
https://doi.org/10.1097/00024382-199902000-00010
https://doi.org/10.1097/00024382-199902000-00010
Publikováno v:
European Respiratory Journal. 13:145-151
Porcine endotoxin shock is characterized by pulmonary hypertension, decreased mean arterial pressure and deteriorated cardiac performance. These pathophysiological findings are accompanied by increased plasma endothelin-1 levels. Previous studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35249c2b354524a0312ff65711fa1fec
https://doi.org/10.1183/09031936.99.13114599
https://doi.org/10.1183/09031936.99.13114599
Autor:
Jan M. Lundberg, Anders Rudehill, Michael Wanecek, Anette Hemsén, Eddie Weitzberg, Agnes Modin
Publikováno v:
British Journal of Pharmacology. 118:617-626
1. To evaluate the possible contribution of endothelin-1 (ET-1) to the pathophysiology of porcine septic shock, the non-peptide, mixed ET-receptor antagonist, bosentan (RO 47-0203) was administered (5 mg kg-1, i.v.) 30 min before infusion of lipopoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c124ad51f4142e59db2003b99862b3
https://doi.org/10.1111/j.1476-5381.1996.tb15446.x
https://doi.org/10.1111/j.1476-5381.1996.tb15446.x
Publikováno v:
Critical Care Medicine. 23:909-918
Objective: To evaluate the possible effects of a combination of systemic nitric oxide synthesis inhibition (to increase mean arterial blood pressure) and nitric oxide inhalation (to decrease pulmonary vascular pressure) in porcine endotoxin shock. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4791fccda2727a0afb2ccbe43e83af82
https://doi.org/10.1097/00003246-199505000-00020
https://doi.org/10.1097/00003246-199505000-00020
Publikováno v:
Acta Anaesthesiologica Scandinavica. 39:50-59
During sepsis vasoactive arachidonic acid metabolites of the cyclo-oxygenase pathway and the endothelium-derived vasoconstrictor endothelin-1 (ET-1) are released. The effects of cyclo-oxygenase pathway inhibition by diclofenac on the endotoxin shock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc50f5e452c8af0782da2debbd8fdd4
https://doi.org/10.1111/j.1399-6576.1995.tb05592.x
https://doi.org/10.1111/j.1399-6576.1995.tb05592.x