Zobrazeno 1 - 10
of 920
pro vyhledávání: '"Anders M, Dale"'
Autor:
Shahram Bahrami, Kaja Nordengen, Jaroslav Rokicki, Alexey A. Shadrin, Zillur Rahman, Olav B. Smeland, Piotr P. Jaholkowski, Nadine Parker, Pravesh Parekh, Kevin S. O’Connell, Torbjørn Elvsåshagen, Mathias Toft, Srdjan Djurovic, Anders M. Dale, Lars T. Westlye, Tobias Kaufmann, Ole A. Andreassen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The basal ganglia are subcortical brain structures involved in motor control, cognition, and emotion regulation. We conducted univariate and multivariate genome-wide association analyses (GWAS) to explore the genetic architecture of basal ga
Externí odkaz:
https://doaj.org/article/2f1f263ef851499c8530865075d76cf0
Autor:
Karoline Kallis, Christopher C. Conlin, Allison Y. Zhong, Troy S. Hussain, Aritrick Chatterjee, Gregory S. Karczmar, Rebecca Rakow-Penner, Anders M. Dale, Tyler M. Seibert
Publikováno v:
Cancer Imaging, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background High b-value diffusion-weighted images (DWI) are used for detection of clinically significant prostate cancer (csPCa). This study qualitatively and quantitatively compares synthesized DWI (sDWI) to acquired (aDWI) for detection of
Externí odkaz:
https://doaj.org/article/5e91fd514a984dd0ab4d436bcca561bb
Autor:
Rongxiang Tang, Erik Buchholz, Anders M. Dale, Robert A. Rissman, Christine Fennema-Notestine, Nathan A. Gillespie, Donald J Hagler, Michael J. Lyons, Michael C. Neale, Matthew S. Panizzon, Olivia K. Puckett, Chandra A. Reynolds, Carol E. Franz, William S. Kremen, Jeremy A. Elman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Plasma neurofilament light chain (NfL) is a promising biomarker of neurodegeneration with potential clinical utility in monitoring the progression of neurodegenerative diseases. However, the cross-sectional associations of plasma
Externí odkaz:
https://doaj.org/article/76973dd443624b90a1ebf2477b1724ec
Autor:
Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Eivind Hovig, Ole A Andreassen, Anders M Dale
Publikováno v:
PLoS Genetics, Vol 20, Iss 8, p e1011372 (2024)
Genome-wide association studies (GWAS) implicate broad genomic loci containing clusters of highly correlated genetic variants. Finemapping techniques can select and prioritize variants within each GWAS locus which are more likely to have a functional
Externí odkaz:
https://doaj.org/article/23cff74853fb4eaeab378868e68ba4fa
Autor:
Sigrun Hope, Alexey A. Shadrin, Aihua Lin, Shahram Bahrami, Linn Rødevand, Oleksandr Frei, Saira J. Hübenette, Weiqiu Cheng, Guy Hindley, Heidi Nag, Line Ulstein, Magdalena Efrim-Budisteanu, Kevin O’Connell, Anders M. Dale, Srdjan Djurovic, Terje Nærland, Ole A. Andreassen
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Autism spectrum disorder (ASD) is a highly heritable condition with a large variation in cognitive function. Here we investigated the shared genetic architecture between cognitive traits (intelligence (INT) and educational attainment (EDU)),
Externí odkaz:
https://doaj.org/article/27f1d6ca47a5452fbc28d5c80e67f33c
Autor:
Lasse Bang, Shahram Bahrami, Guy Hindley, Olav B. Smeland, Linn Rødevand, Piotr P. Jaholkowski, Alexey Shadrin, Kevin S. O’ Connell, Oleksandr Frei, Aihua Lin, Zillur Rahman, Weiqiu Cheng, Nadine Parker, Chun C. Fan, Anders M. Dale, Srdjan Djurovic, Cynthia M. Bulik, Ole A. Andreassen
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Anorexia nervosa (AN) is a heritable eating disorder (50–60%) with an array of commonly comorbid psychiatric disorders and related traits. Although significant genetic correlations between AN and psychiatric disorders and related traits ha
Externí odkaz:
https://doaj.org/article/1504dcdb9170486786ab8df09684f946
Autor:
Markos Tesfaye, Piotr Jaholkowski, Guy F. L. Hindley, Alexey A. Shadrin, Zillur Rahman, Shahram Bahrami, Aihua Lin, Børge Holen, Nadine Parker, Weiqiu Cheng, Linn Rødevand, Oleksandr Frei, Srdjan Djurovic, Anders M. Dale, Olav B. Smeland, Kevin S. O’Connell, Ole A. Andreassen
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Irritable bowel syndrome (IBS) often co-occurs with psychiatric and gastrointestinal disorders. A recent genome-wide association study (GWAS) identified several genetic risk variants for IBS. However, most of the heritability rema
Externí odkaz:
https://doaj.org/article/d4cf61f95eec4b69bd69fd5c62edd34e
Autor:
Maren M. Sjaastad Andreassen, Stephane Loubrie, Michelle W. Tong, Lauren Fang, Tyler M. Seibert, Anne M. Wallace, Somaye Zare, Haydee Ojeda-Fournier, Joshua Kuperman, Michael Hahn, Neil P. Jerome, Tone F. Bathen, Ana E. Rodríguez-Soto, Anders M. Dale, Rebecca Rakow-Penner
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeDynamic contrast-enhanced MRI (DCE) and apparent diffusion coefficient (ADC) are currently used to evaluate treatment response of breast cancer. The purpose of the current study was to evaluate the three-component Restriction Spectrum Imaging
Externí odkaz:
https://doaj.org/article/51223c94fb14463c96416be583347c3c
Autor:
Dennis van der Meer, Tiril P. Gurholt, Ida E. Sønderby, Alexey A. Shadrin, Guy Hindley, Zillur Rahman, Ann-Marie G. de Lange, Oleksandr Frei, Olof D. Leinhard, Jennifer Linge, Rozalyn Simon, Dani Beck, Lars T. Westlye, Sigrun Halvorsen, Anders M. Dale, Tom H. Karlsen, Tobias Kaufmann, Ole A. Andreassen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
A GWAS study of European individuals uncovers genetic associations between whole-body MRI derived measures and cardiometabolic diseases and highlights the key role of liver fat in cardiometabolic health.
Externí odkaz:
https://doaj.org/article/ad41b0e9ff9a4483a5272677e670f9b7
Autor:
Vera Fominykh, Alexey A. Shadrin, Piotr P. Jaholkowski, Shahram Bahrami, Lavinia Athanasiu, Douglas P. Wightman, Emil Uffelmann, Danielle Posthuma, Geir Selbæk, Anders M. Dale, Srdjan Djurovic, Oleksandr Frei, Ole A. Andreassen
Publikováno v:
Neurobiology of Disease, Vol 183, Iss , Pp 106174- (2023)
Background: Neuroinflammation is involved in the pathophysiology of Alzheimer's disease (AD), including immune-linked genetic variants and molecular pathways, microglia and astrocytes. Multiple Sclerosis (MS) is a chronic, immune-mediated disease wit
Externí odkaz:
https://doaj.org/article/9dd297411ea742c6a886b3b00b2f2ea5