Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anders Lignell"'
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background Invasive candidiasis (IC) is a severe and often fatal fungal infection that affects critically ill patients. The development of animal models that mimic human disease is essential for advancing our understanding of IC pathophysiol
Externí odkaz:
https://doaj.org/article/b25da35f0a2d49c5ba7b1ca24bd63ed3
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:3099-3104
It is generally accepted that only the unbound fraction of a drug is pharmacologically active. Posaconazole is an antifungal agent with a protein binding of 98 to 99%. Taking into account the degree of protein binding, plasma levels in patients, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736caead4bd41ee0441b4780ac492847
https://doi.org/10.1128/aac.01671-10
https://doi.org/10.1128/aac.01671-10
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:1629-1637
An antagonistic effect of voriconazole on the fungicidal activity of sequential doses of amphotericin B has previously been demonstrated in Candida albicans strains susceptible to voriconazole. Because treatment failure and the need to switch to othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265af7b1d8b693eac52d7a166690692f
https://doi.org/10.1128/aac.00791-10
https://doi.org/10.1128/aac.00791-10
Publikováno v:
Clinical Microbiology and Infection. 13(6):613-619
The aim of this study was to develop and validate a new in-vitro kinetic model for the combination of two drugs with different half-lives, and to use this model for the study of the pharmacodynamic effects of amphotericin B and voriconazole, alone or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0f21aa9133727c9a3f1ed378280673
Publikováno v:
Acta Anaesthesiologica Scandinavica. 47:897-900
Background: Activated protein C has recently been shown in a multicentre trial to significantly reduce mortality in patients with septic shock. There are also some case reports and minor studies demonstrating promising results with the unactivated fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72430fe066508c55e175d1c08199867d
https://doi.org/10.1034/j.1399-6576.2003.00075.x
https://doi.org/10.1034/j.1399-6576.2003.00075.x
Publikováno v:
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 117(8)
Here we report two rare cases of severe thoracic Aspergillus fumigatus infections after lung and heart surgery at the same thoracic intensive care unit at the same time. The main objective was to identify a possible source of transmission. With arbit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802ed570c683299fe75e1b2b98379de9
https://pubmed.ncbi.nlm.nih.gov/19664127
https://pubmed.ncbi.nlm.nih.gov/19664127
Publikováno v:
The Journal of antimicrobial chemotherapy. 62(1)
Pharmacodynamic studies are important for the optimal use of antimicrobial agents. Combination antifungal therapy may be one method to improve outcome in invasive Candida infections. An in vitro kinetic model to study the pharmacodynamic effects of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a4961ff94d8e19165a3278b9ea4361
https://pubmed.ncbi.nlm.nih.gov/18408237
https://pubmed.ncbi.nlm.nih.gov/18408237
Publikováno v:
Journal of Antimicrobial Chemotherapy (JAC); Jul2008, Vol. 62 Issue 1, p142-142, 1p