Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anders Handrup Kverneland"'
Autor:
Marco Donia, Özcan Met, Julie Westerlin Kjeldsen, Sine Reker Hadrup, Inge Marie Svane, Arianna Draghi, Anders Handrup Kverneland, Christina Heeke, Siri Amanda Tvingsholm, Marcus Svensson Frej, Vibeke Mindahl Rafa, Ulla Kring Hansen, Maria Ormhøj, Alexander Tyron, Agnete W P Jensen, Mohammad Kadivar, Amalie Kai Bentzen, Kamilla K Munk, Gitte N Aasbjerg, Jeppe S H Ternander, Tripti Tamhane, Christian Schmess, Samuel A. Funt, Søren Nyboe Jakobsen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Adoptive cell therapy (ACT) has shown promising results for the treatment of cancer and viral infections. Successful ACT relies on ex vivo expansion of large numbers of desired T-cells with strong cytotoxic capacity and in vivo persistence
Externí odkaz:
https://doaj.org/article/a25dad34aae2492e8875e883c1894921
Autor:
Christopher Aled Chamberlain, Eric Paul Bennett, Anders Handrup Kverneland, Inge Marie Svane, Marco Donia, Özcan Met
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 417-428 (2022)
Adoptive T cell therapy (ACT) with expanded tumor-infiltrating lymphocytes (TIL) can induce durable responses in cancer patients from multiple histologies, with response rates of up to 50%. Antibodies blocking the engagement of the inhibitory recepto
Externí odkaz:
https://doaj.org/article/e7d0ab4e5744431699de187f51ed9968
Autor:
Marco Donia, Troels Holz Borch, Özcan Met, Julie Westerlin Kjeldsen, Morten Nielsen, Inge Marie Svane, Anders Handrup Kverneland, Christopher Aled Chamberlain, Sofie Kirial Mørk, Cathrine Lund Lorentzen, Lise Pyndt Jørgensen, Lene Buhl Riis, Christina Westmose Yde
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/f0af08021a4a4bf1a713d50b686b096c
Autor:
Marco Donia, Rikke Andersen, Troels Holz Borch, Per Kongsted, Özcan Met, Julie Westerlin Kjeldsen, Morten Nielsen, Magnus Pedersen, Martin Lauss, Göran Jönsson, Inge Marie Svane, Katja Harbst, Aynal Haque Rana, Evelina Martinenaite, Anders Handrup Kverneland, Lisbet Rosenkrantz Hölmich, Helle Hendel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Purpose Despite impressive response rates following adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, improvement is needed to increase the efficacy and broaden the applicability of this treat
Externí odkaz:
https://doaj.org/article/441c3fb225154f6cb0e893421b425aa3
Autor:
Eric Paul Bennett, Özcan Met, Christopher Chamberlain, Marco Donia, Anders Handrup Kverneland, Inge Marie Svane
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss, Pp 417-428 (2022)
Chamberlain, C A, Bennett, E P, Kverneland, A H, Svane, I M, Donia, M & Met, Ö 2022, ' Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy ', Molecular Therapy-Oncolytics, vol. 24, pp. 417-428 . https://doi.org/10.1016/j.omto.2022.01.004
Chamberlain, C A, Bennett, E P, Kverneland, A H, Svane, I M, Donia, M & Met, Ö 2022, ' Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy ', Molecular Therapy-Oncolytics, vol. 24, pp. 417-428 . https://doi.org/10.1016/j.omto.2022.01.004
Adoptive T cell therapy (ACT) with expanded tumor-infiltrating lymphocytes (TIL) can induce durable responses in cancer patients from multiple histologies, with response rates of up to 50%. Antibodies blocking the engagement of the inhibitory recepto
Autor:
Joachim Granhøj, Henrik Sengeløv, Anders Handrup Kverneland, Marco Donia, Troels Holz Borch, Inge Marie Svane
Publikováno v:
Cytotherapy. 23(8)
Background aims Lymphodepletion with non-myeloablative (NMA) chemotherapy is currently a prerequisite for adoptive cell therapy (ACT). ACT based on tumor-infiltrating lymphocytes has long been used in malignant melanoma (MM), but with the advance of
Autor:
Katja Harbst, Özcan Met, T.H. Borch, Anders Handrup Kverneland, Marco Donia, Magnus Pedersen, Göran Jönsson, Christina Friese, Inge Marie Svane, Marie Christine Wulff Westergaard
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Friese, C, Harbst, K, Borch, T H, Westergaard, M C W, Pedersen, M, Kverneland, A, Jönsson, G, Donia, M, Svane, I M & Met, Ö 2020, ' CTLA-4 blockade boosts the expansion of tumor-reactive CD8 + tumor-infiltrating lymphocytes in ovarian cancer ', Scientific Reports, vol. 10, no. 1, 3914 . https://doi.org/10.1038/s41598-020-60738-4
Scientific Reports
Friese, C, Harbst, K, Borch, T H, Westergaard, M C W, Pedersen, M, Kverneland, A, Jönsson, G, Donia, M, Svane, I M & Met, Ö 2020, ' CTLA-4 blockade boosts the expansion of tumor-reactive CD8 + tumor-infiltrating lymphocytes in ovarian cancer ', Scientific Reports, vol. 10, no. 1, 3914 . https://doi.org/10.1038/s41598-020-60738-4
Adoptive cell therapy (ACT) with autologous tumor-infiltrating lymphocytes (TILs) can induce durable complete tumor regression in patients with advanced melanoma. Efforts are currently underway to expand this treatment modality to other cancer types.
Autor:
Lars Rønn Olsen, Brad H. Nelson, Sjoerd H. van der Burg, Morten Nielsen, Özcan Met, Saskia J. A. M. Santegoets, Magnus Pedersen, Troels Holz Borch, Inge Marie Svane, Marco Donia, Anders Handrup Kverneland, Katy Milne, Gitte Aasbjerg, Marie Christine Wulff Westergaard
Publikováno v:
Kverneland, A H, Pedersen, M, Westergaard, M C W, Nielsen, M, Borch, T H, Olsen, L R, Aasbjerg, G, Santegoets, S J, van der Burg, S H, Milne, K, Nelson, B H, Met, Ö, Donia, M & Svane, I M 2020, ' Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer ', OncoTarget, vol. 11, no. 22, pp. 2092-2105 . https://doi.org/10.18632/oncotarget.27604
Oncotarget
Kverneland, A H, Pedersen, M, Wulff Westergaard, M C, Nielsen, M, Borch, T H, Olsen, L R, Aasbjerg, G, Santegoets, S J, van der Burg, S H, Milne, K, Nelson, B H, Met, Ö, Donia, M & Svane, I M 2020, ' Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer ', OncoTarget, vol. 11, no. 22, pp. 2092-2105 . https://doi.org/10.18632/oncotarget.27604
Oncotarget
Kverneland, A H, Pedersen, M, Wulff Westergaard, M C, Nielsen, M, Borch, T H, Olsen, L R, Aasbjerg, G, Santegoets, S J, van der Burg, S H, Milne, K, Nelson, B H, Met, Ö, Donia, M & Svane, I M 2020, ' Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer ', OncoTarget, vol. 11, no. 22, pp. 2092-2105 . https://doi.org/10.18632/oncotarget.27604
Immune therapy is a promising field within oncology but has been unsuccessful in ovarian cancer (OC). Still, there is rationale and evidence supporting immune therapy in OC. We investigated the potential for adoptive cell therapy (ACT) from in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59b418f23f195dfd05b12d4c8ef32b1
https://orbit.dtu.dk/en/publications/45f2e1bc-a069-411d-95dd-019d81706191
https://orbit.dtu.dk/en/publications/45f2e1bc-a069-411d-95dd-019d81706191
Autor:
Neel Ingemann Nissen, Christina Jensen, Anders Handrup Kverneland, Marco Donia, Inge Marie Svane, Nicholas Willumsen, Morten A. Karsdal
Publikováno v:
Cancer Research. 81:388-388
Background: Biomarkers for predicting immune checkpoint inhibitor (ICI) efficacy are essential for patient selection for current ICI regimens and new combination therapies. Patients with T-cell excluded tumors have poor effect on ICI therapy. T-cell
Autor:
Christina Jensen, Anders Handrup Kverneland, Marco Donia, Joachim Høg Mortensen, Nicholas Willumsen, Inge Marie Svane, Morten A. Karsdal
Publikováno v:
Cancer Research. 81:386-386
Background: Peripheral biomarkers associated with response and resistance to anti-PD-1 therapy in metastatic melanoma patients represent an unmet medical need. High neutrophil activity is associated with immune checkpoint inhibitor failure, amongst o