Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Anders H Lund"'
Autor:
Marion Horsch, Juan Antonio Aguilar-Pimentel, Clemens Bönisch, Christophe Côme, Cathrine Kolster-Fog, Klaus T Jensen, Anders H Lund, Icksoo Lee, Lawrence I Grossman, Christopher Sinkler, Maik Hüttemann, Erwin Bohn, Helmut Fuchs, Markus Ollert, Valérie Gailus-Durner, Martin Hrabĕ de Angelis, Johannes Beckers
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134503 (2015)
We established a selection strategy to identify new models for an altered airway inflammatory response from a large compendium of mutant mouse lines that were systemically phenotyped in the German Mouse Clinic (GMC). As selection criteria we included
Externí odkaz:
https://doaj.org/article/eb5e849edd9e468185aae4a588743bdb
Autor:
Gustavo Stadthagen, Disa Tehler, Nina Molin Høyland-Kroghsbo, Jiayu Wen, Anders Krogh, Klaus T Jensen, Eric Santoni-Rugiu, Lars H Engelholm, Anders H Lund
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003913 (2013)
miRNAs are small regulatory RNAs that, due to their considerable potential to target a wide range of mRNAs, are implicated in essentially all biological process, including cancer. miR-10a is particularly interesting considering its conserved location
Externí odkaz:
https://doaj.org/article/0f9aa5d312684355b6d05c261a3f76dd
Autor:
Lukas T Jeker, Xuyu Zhou, Kseniya Gershberg, Dimitri de Kouchkovsky, Malika M Morar, Gustavo Stadthagen, Anders H Lund, Jeffrey A Bluestone
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36684 (2012)
MicroRNAs (miRNAs) are crucial for regulatory T cell (Treg) stability and function. We report that microRNA-10a (miR-10a) is expressed in Tregs but not in other T cells including individual thymocyte subsets. Expression profiling in inbred mouse stra
Externí odkaz:
https://doaj.org/article/2130618c004c4436be4393e71590b5da
Autor:
Youjia Hua, Shiwei Duan, Andrea E Murmann, Niels Larsen, Jørgen Kjems, Anders H Lund, Marcus E Peter
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26521 (2011)
micro(mi)RNAs are small non-coding RNAs that negatively regulate expression of most mRNAs. They are powerful regulators of various differentiation stages, and the expression of genes that either negatively or positively correlate with expressed miRNA
Externí odkaz:
https://doaj.org/article/3634f0c5ed6c447a90cb4767685a3a41
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8836 (2010)
BackgroundMicroRNAs (miRNAs) have emerged as important gene regulators and are recognized as key players in tumorigenesis. miR-145 is reported to be down-regulated in several cancers, but knowledge of its targets in colon cancer remains limited.Metho
Externí odkaz:
https://doaj.org/article/d03cd24fb2eb43119c3b7ca7774005f5
Autor:
Jiajia Xi, Goda Snieckute, José Francisco Martínez, Frederic Schrøder Wenzel Arendrup, Abhishek Asthana, Christina Gaughan, Anders H. Lund, Simon Bekker-Jensen, Robert H. Silverman
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113998- (2024)
Summary: RNase L is an endoribonuclease of higher vertebrates that functions in antiviral innate immunity. Interferons induce oligoadenylate synthetase enzymes that sense double-stranded RNA of viral origin leading to the synthesis of 2′,5′-oligo
Externí odkaz:
https://doaj.org/article/4bee6a745ac8417daa16573750078491
Autor:
Laura Ryder, Frederic Schrøder Arendrup, José Francisco Martínez, Goda Snieckute, Chiara Pecorari, Riyaz Ahmad Shah, Anders H. Lund, Melanie Blasius, Simon Bekker-Jensen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-10 (2023)
Abstract Impairment of protein translation can cause stalling and collision of ribosomes and is a signal for the activation of ribosomal surveillance and rescue pathways. Despite clear evidence that ribosome collision occurs stochastically at a cellu
Externí odkaz:
https://doaj.org/article/f8cffef743ee4b129b054cb825d27f9d
Autor:
Kishor Gawade, Patrycja Plewka, Sophia J. Häfner, Anders H. Lund, Virginie Marchand, Yuri Motorin, Michal W. Szczesniak, Katarzyna D. Raczynska
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract FUS is a multifunctional protein involved in many aspects of RNA metabolism, including transcription, splicing, translation, miRNA processing, and replication-dependent histone gene expression. In this work, we show that FUS depletion result
Externí odkaz:
https://doaj.org/article/305ea8adfd974367b7a37f4dd385f3f3
Publikováno v:
Cells, Vol 12, Iss 7, p 990 (2023)
It is well established that mutations in the canonical WNT-signalling pathway play a major role in various cancers. Critical to developing new therapeutic strategies is understanding which cancers are driven by WNT pathway activation and at what leve
Externí odkaz:
https://doaj.org/article/dd978339ad6840da8e56975c0c3f4072
Autor:
Maarten van Lohuizen, Anton Berns, Lodewyk Wessels, David J. Adams, Jane Rogers, Jos Jonkers, Anders H. Lund, Jack Lenz, Colin Pritchard, Jules Gadiot, Paul Krimpenfort, Wendy Lagcher, Konstantin Matentzoglu, Miranda van Uitert, Geoffrey Turner, Jeroen de Ridder, Daoud Sie, Carla P. Martins, Anthony G. Uren, Jaap Kool
Supplementary Table 4 from Insertional Mutagenesis in Mice Deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b00b83e5583745650bd7a3120fdfdc
https://doi.org/10.1158/0008-5472.22385417.v1
https://doi.org/10.1158/0008-5472.22385417.v1