Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anders E, Hansen"'
Autor:
Peng Wei, Cecilia Romanò, Chengxin Li, Gael Clergeaud, Thomas L. Andresen, Jonas R. Henriksen, Anders E. Hansen, Mads H. Clausen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Diseases caused by S. pneumoniae are the leading cause of child mortality. As antibiotic resistance of S. pneumoniae is rising, vaccination remains the most recommended solution. However, the existing pneumococcal polysaccharides vaccine (Pn
Externí odkaz:
https://doaj.org/article/540af2119b674c7fa394089f468d88b1
Autor:
Sophie B. Jensen, Ditte E. Jæhger, Elizabeth Serrano-Chávez, Hólmfríður R. Halldórsdóttir, Trine B. Engel, Jennifer S. Jørgensen, Unnur J. Björgvinsdóttir, Serhii Kostrikov, Marouschka J. Scheeper, Lars Ringgaard, Linda M. Bruun, Camilla Stavnsbjerg, Esben Christensen, Martin Bak, Julianna Thuroczy, Lajos Balogh, Andreas T. I. Jensen, Fredrik Melander, Andreas Kjaer, Jonas R. Henriksen, Anders E. Hansen, Thomas L. Andresen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cancer curing immune responses against heterogeneous solid cancers require that a coordinated immune activation is initiated in the antigen avid but immunosuppressive tumor microenvironment (TME). The plastic TME, and the poor systemic toler
Externí odkaz:
https://doaj.org/article/d50340662d0947fe879e809163698218
Autor:
Ditte E. Jæhger, Mie L. Hübbe, Martin K. Kræmer, Gael Clergeaud, André V. Olsen, Camilla Stavnsbjerg, Mette N. Wiinholt, Andreas Kjær, Jonas R. Henriksen, Anders E. Hansen, Thomas L. Andresen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Adoptive T-cell transfer (ACT) offers a curative therapeutic option for subsets of melanoma and hematological cancer patients. To increase response rates and broaden the applicability of ACT, it is necessary to improve the post-infusion perf
Externí odkaz:
https://doaj.org/article/a35c9f9e5f3d461484acacf388c2f25e
Autor:
Serhii Kostrikov, Kasper B. Johnsen, Thomas H. Braunstein, Johann M. Gudbergsson, Frederikke P. Fliedner, Elisabeth A. A. Obara, Petra Hamerlik, Anders E. Hansen, Andreas Kjaer, Casper Hempel, Thomas L. Andresen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Kostrikov et al. report a deficiency of transcardial perfusion in brain tumor vasculature, which leads to exaggeration of drug extravasation measurements. They then demonstrate how optical tissue clearing can help to overcome this limitation and prov
Externí odkaz:
https://doaj.org/article/351a278571824c1bab11d20eb4f1160f
Autor:
Dennis Pedersbæk, Louise Krogager, Camilla Hald Albertsen, Lars Ringgaard, Anders E. Hansen, Katrine Jønsson, Jannik B. Larsen, Andreas Kjær, Thomas L. Andresen, Jens B. Simonsen
Publikováno v:
ACS Omega, Vol 6, Iss 1, Pp 871-880 (2020)
Externí odkaz:
https://doaj.org/article/c59234b1e39344ffaad670023bf12b2c
Autor:
Elise Konradsson, Maja L. Arendt, Kristine Bastholm Jensen, Betina Børresen, Anders E. Hansen, Sven Bäck, Annemarie T. Kristensen, Per Munck af Rosenschöld, Crister Ceberg, Kristoffer Petersson
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
FLASH radiotherapy has emerged as a treatment technique with great potential to increase the differential effect between normal tissue toxicity and tumor response compared to conventional radiotherapy. To evaluate the feasibility of FLASH radiotherap
Externí odkaz:
https://doaj.org/article/df18f26929944fe6885a4c197de5e0e6
Autor:
Neil J. Borthwick, Caitlin L. Maikawa, Sven Weller, Thomas L. Andresen, Anders E. Hansen, Anton A.A. Autzen
TLR 7/8 agonists are highly potent immunostimulators, though their clinical translation has been met with mixed success, due to their high toxicity as a result of an unregulated systemic immune activation. There is enormous potential to augment cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::834710bf8dda225ef4602ee720ad4ee3
https://doi.org/10.1101/2023.03.23.533909
https://doi.org/10.1101/2023.03.23.533909
Autor:
Camilla Stavnsbjerg, Esben Christensen, Rasmus Münter, Jonas R. Henriksen, Matthias Fach, Ladan Parhamifar, Camilla Christensen, Andreas Kjaer, Anders E. Hansen, Thomas L. Andresen
Publikováno v:
Stavnsbjerg, C, Christensen, E, Münter, R, Henriksen, J R, Fach, M, Parhamifar, L, Christensen, C, Kjaer, A, Hansen, A E & Andresen, T L 2022, ' Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists ', Journal of controlled release, vol. 342, pp. 337-344 . https://doi.org/10.1016/j.jconrel.2021.12.033
Systemic administration of toll-like receptor (TLR) agonists have demonstrated impressive preclinical results as an anti-cancer therapy due to their potent innate immune-stimulatory properties. The clinical advancement has, however, been hindered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617c818b4e1fea03f053b99581939a5c
https://doi.org/10.1016/j.jconrel.2021.12.033
https://doi.org/10.1016/j.jconrel.2021.12.033
Autor:
Kamilla Westarp Zornhagen, Malene M. Clausen, Anders E. Hansen, Ian Law, Fintan J. McEvoy, Svend A. Engelholm, Andreas Kjær, Annemarie T. Kristensen
Publikováno v:
Diagnostics, Vol 5, Iss 3, Pp 372-382 (2015)
Glycolysis, hypoxia, and proliferation are important factors in the tumor microenvironment contributing to treatment-resistant aggressiveness. Imaging these factors using combined functional positron emission tomography and computed tomography can po
Externí odkaz:
https://doaj.org/article/f6dee9656953426aa1b6e4a371499e6b
Autor:
Kamilla Westarp Zornhagen, Anders E Hansen, Jytte Oxboel, Andreas E Clemmensen, Henrik H El Ali, Annemarie T Kristensen, Andreas Kjær
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141379 (2015)
Tumour microenvironment heterogeneity is believed to play a key role in cancer progression and therapy resistance. However, little is known about micro regional distribution of hypoxia, glycolysis and proliferation in spontaneous solid tumours. The o
Externí odkaz:
https://doaj.org/article/fe7be8303575498db6223a9ff4f5695c