Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Anders Dige"'
Autor:
Frida Gorreja, Mia Bendix, Stephen T. A. Rush, Lujain Maasfeh, Otto Savolainen, Anders Dige, Jorgen Agnholt, Lena Öhman, Maria K. Magnusson
Publikováno v:
Cells, Vol 13, Iss 1, p 60 (2023)
Intestinal macrophages and fibroblasts act as microenvironmental sentinels mediating inflammation and disease progression in Crohn’s disease (CD). We aimed to establish the effects of fecal supernatants (FSs) from patients with CD on macrophage and
Externí odkaz:
https://doaj.org/article/e621b314c63240b4b7241ae70d60f38b
Autor:
Trine Bay Laurberg, Anne Gitte Loft, Robin Christensen, Anders Dige, Kasper Fjellhaugen Hjuler, Lars Iversen, Jørgen Agnholt, Louise Faurskov Møller
Publikováno v:
BMJ Open, Vol 11, Iss 4 (2021)
Introduction Immune-mediated inflammatory diseases (IMIDs) are associated with reduced health-related quality of life (HRQol), increased risk of somatic and psychiatric comorbidities and reduced socioeconomic status. Individuals with one IMID have an
Externí odkaz:
https://doaj.org/article/df095523ea5c45469bf9af8e2e2e1f55
Autor:
Mia Bendix, Anders Dige, Søren Peter Jørgensen, Jens Frederik Dahlerup, Bo Martin Bibby, Bent Deleuran, Jørgen Agnholt
Publikováno v:
Nutrients, Vol 13, Iss 4, p 1083 (2021)
Background: Seven weeks of high-dose vitamin D treatment decreases intestinal IL17A and IFN-γ mRNA expression in active Crohn’s disease (CD). In this follow-up study, we investigated whether seven-week vitamin D treatment affected the infliximab r
Externí odkaz:
https://doaj.org/article/43509916f19a46b18c9a20ade88c5a6c
Autor:
Mia Bendix, Anders Dige, Søren Peter Jørgensen, Jens Frederik Dahlerup, Bo Martin Bibby, Bent Deleuran, Jørgen Agnholt
Publikováno v:
Nutrients, Vol 12, Iss 12, p 3699 (2020)
Background: Vitamin D treatment may reduce Crohn’s disease (CD) activity by modulating the mucosal immune function. We investigated if high-dose vitamin D +/− infliximab modulated the mucosal cytokine expression in active CD. Methods: Forty CD pa
Externí odkaz:
https://doaj.org/article/cb72e89f8e1e40c5b76e5caea21934f6
Autor:
Anders Dige, Maria K. Magnusson, Claus Uhrenholt, Tue Kruse Rasmussen, Tue Kragstrup, Lena Öhman, Jens Dahlerup, Jørgen Agnholt
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
T helper 17 (Th17) cells produce interleukin (IL) 17-A. In addition, Th17 cells produce IL-21 and IL-22. Th17 cells have a disease-promoting role in Crohn’s disease (CD). We investigated the effects of anti-TNFα treatment on mucosal gene expressio
Externí odkaz:
https://doaj.org/article/dbddb8ae1a704f44b93d0cad67442194
Autor:
Stine Hald, Anne Grethe Schioldan, Mary E Moore, Anders Dige, Helle Nygaard Lærke, Jørgen Agnholt, Knud Erik Bach Knudsen, Kjeld Hermansen, Maria L Marco, Søren Gregersen, Jens F Dahlerup
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159223 (2016)
Recently, the intestinal microbiota has been emphasised as an important contributor to the development of metabolic syndrome. Dietary fibre may exert beneficial effects through modulation of the intestinal microbiota and metabolic end products. We in
Externí odkaz:
https://doaj.org/article/133e488479df47b0bff28bcf5e69005d
Autor:
Ane Bjerg Christensen, Anders Dige, Johan Vad-Nielsen, Christel R. Brinkmann, Mia Bendix, Lars Østergaard, Martin Tolstrup, Ole S. Søgaard, Thomas A. Rasmussen, Jens Randel Nyengaard, Jørgen Agnholt, Paul W. Denton
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Intestinal CD4+ T cell depletion is rapid and profound during early HIV-1 infection. This leads to a compromised mucosal barrier that prompts chronic systemic inflammation. The preferential loss of intestinal T helper 17 (Th17) cells in HIV-1 disease
Externí odkaz:
https://doaj.org/article/c48f33158abe4fee980a84eeac56fe73
Autor:
Anders G Kjærgaard, Sidsel Rødgaard-Hansen, Anders Dige, Jan Krog, Holger J Møller, Else Tønnesen
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92331 (2014)
BACKGROUND: The diagnosis of sepsis is challenging and there is an unmet need for sensitive and specific diagnostic and prognostic biomarkers. Following activation of macrophages and monocytes, the haptoglobin-haemoglobin receptor (CD163) and the man
Externí odkaz:
https://doaj.org/article/0040a470c3d0406ba73f404eb3accf61
Autor:
Jens Kelsen, Anders Dige, Heinrich Schwindt, Francesco D'Amore, Finn S Pedersen, Jørgen Agnholt, Lisbet A Christensen, Jens F Dahlerup, Christian L Hvas
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17890 (2011)
BackgroundConcominant with the widespread use of combined immunotherapy in the management of Crohn's disease (CD), the incidence of hepato-splenic gamma-delta (γδ)-T cell lymphoma has increased sharply in CD patients. Malignant transformation of ly
Externí odkaz:
https://doaj.org/article/9513996591934d85848070cc69d43a23
Autor:
Johan F K F Ilvemark, Rune Wilkens, Peter Thielsen, Anders Dige, Trine Boysen, Jørn Brynskov, Jacob Tveiten Bjerrum, Jakob Benedict Seidelin
Publikováno v:
Ilvemark, J F K F, Wilkens, R, Thielsen, P, Dige, A, Boysen, T, Brynskov, J, Bjerrum, J T & Seidelin, J B 2022, ' Early Intestinal Ultrasound Predicts Intravenous Corticosteroid Response in Hospitalised Patients With Severe Ulcerative Colitis ', Journal of Crohn's & Colitis, vol. 16, no. 11, pp. 1725-1734 . https://doi.org/10.1093/ecco-jcc/jjac083
Background and Aims Our aim was to determine if transabdominal intestinal ultrasound changes after 48 ± 24 h of intravenous corticosteroids can predict treatment outcomes in hospitalised patients with severe ulcerative colitis. Methods We performed