Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anders Dagälv"'
Autor:
Anders, Dagälv, Anders, Lundequist, Beata, Filipek-Górniok, Tabea, Dierker, Inger, Eriksson, Lena, Kjellén
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2303
Heparan sulfate proteoglycans are important modulators of cellular processes where the negatively charged polysaccharide chains interact with target proteins. The sulfation pattern of the heparan sulfate chains will determine the proteins that will b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a4cec2925c9b073c343470d00876f56c
https://pubmed.ncbi.nlm.nih.gov/34626376
https://pubmed.ncbi.nlm.nih.gov/34626376
Autor:
Lena Kjellén, Audrey Deligny, Alison V. Nairn, Anders Lundequist, Tabea Dierker, Anders Dagälv, Catherine L.R. Merry, Inger Eriksson, Kelley W. Moremen
Publikováno v:
Journal of Biological Chemistry. 291:18600-18607
Analysis of heparan sulfate synthesized by HEK 293 cells overexpressing murine NDST1 and/or NDST2 demonstrated that the amount of heparan sulfate was increased in NDST2- but not in NDST1-overexpressing cells. Altered transcript expression of genes en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7de433ce16d909cdc032d8560290131
https://doi.org/10.1074/jbc.m116.744433
https://doi.org/10.1074/jbc.m116.744433
Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells*
Autor:
Soumi Kundu, Karin Forsberg-Nilsson, Anders Dagälv, Katarina Holmborn, Maud Forsberg, Lena Kjellén
Publikováno v:
The Journal of Biological Chemistry
Background: HSPG interacts with growth factors to influence growth and differentiation. Results: ES cells lacking NDST1 and NDST2 show very limited differentiation potential. FGF and heparin rescued formation of neural progenitors. Conclusion: HS-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b40a3f5c5f22c9152bbd3092409ddc0
http://europepmc.org/articles/PMC3322844
http://europepmc.org/articles/PMC3322844
Autor:
Ananya, Roy, Osama, Sawesi, Ulrika, Pettersson, Anders, Dagälv, Lena, Kjellén, Anna, Lundén, Magnus, Åbrink
Publikováno v:
BMC Immunology
Background Serglycin proteoglycans are essential for maturation of secretory granules and for the correct granular storage of cationic proteases in hematopoietic cells, e.g. mast cells. However, little is known about the in vivo functions of serglyci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9e443c5747b094782c7da51dc8ca97c
https://pubmed.ncbi.nlm.nih.gov/27267469
https://pubmed.ncbi.nlm.nih.gov/27267469
Autor:
Lena Kjellén, Beata Filipek-Górniok, Tabea Dierker, Anders Dagälv, Inger Eriksson, Anders Lundequist
Publikováno v:
Methods in Molecular Biology ISBN: 9781493917136
Methods in Molecular Biology ISBN: 9781071613979
Methods in Molecular Biology ISBN: 9781071613979
Heparan sulfate proteoglycans are important modulators of cellular processes where the negatively charged polysaccharide chains interact with target proteins. The sulfation pattern of the heparan sulfate chains will determine which proteins will bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b4e5253bb2abec18b66747f669cbfc
https://doi.org/10.1007/978-1-4939-1714-3_17
https://doi.org/10.1007/978-1-4939-1714-3_17
Autor:
Osama Sawesi, Susan M. Schlenner, Hans Reimer Rodewald, Sara Bolin, Anders Dagälv, Helena Sippola, Ananya Roy, Lena Kjellén, Lars Hellman, Thorsten B. Feyerabend, Goutham Ganesh, Magnus Åbrink
During infection and tissue damage, virulence factors and alarmins are pro-inflammatory and induce activation of various immune cells including macrophages and mast cells (MCs). Activated MCs instantly release preformed inflammatory mediators, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8328fcae34c0a45d4db764dda8495b9b
https://europepmc.org/articles/PMC3879547/
https://europepmc.org/articles/PMC3879547/
Autor:
Audrey Deligny, Wei Wei, Rebecca J. Holley, Catherine L.R. Merry, Anders Dagälv, Brian W. Bigger, Milady R. Niñonuevo, Lena Kjellén, Julie A. Leary, H. Angharad Watson
Publikováno v:
The Journal of biological chemistry. 286(43)
Mucopolysaccharide (MPS) diseases are characterized by accumulation of glycosaminoglycans (GAGs) due to deficiencies in lysosomal enzymes responsible for GAG breakdown. Using a murine model of MPSI Hurler (MPSIH), we have quantified the heparan sulfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da8767a62298e140bc5a8a4412c0bb2
https://pubmed.ncbi.nlm.nih.gov/21873421
https://pubmed.ncbi.nlm.nih.gov/21873421
Publikováno v:
Journal of Biological Chemistry. 287:11282
Deficiency of the heparan sulfate biosynthesis enzyme N-deacetylase/N-sulfotransferase 1 (NDST1) in mice causes severely disturbed heparan sulfate biosynthesis in all organs, whereas lack of NDST2 only affects heparin biosynthesis in mast cells (MCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb17bff9fafc8e0ea77e8598108a9c81
https://doi.org/10.1074/jbc.a111.303891
https://doi.org/10.1074/jbc.a111.303891