Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Anders, Nygren"'
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225245 (2019)
Mathematical models of cardiac cells have been established to broaden understanding of cardiac function. In the process of developing electrophysiological models for cardiac myocytes, precise parameter tuning is a crucial step. The membrane resistanc
Externí odkaz:
https://doaj.org/article/4b70edf3482a4f219129d4759e9c18ef
Autor:
Andreas Brodehl, Darrell D Belke, Lauren Garnett, Kristina Martens, Nelly Abdelfatah, Marcela Rodriguez, Catherine Diao, Yong-Xiang Chen, Paul M K Gordon, Anders Nygren, Brenda Gerull
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174019 (2017)
BACKGROUND:Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder leading to ventricular arrhythmias and heart failure, mainly as a result of mutations in cardiac desmosomal genes. Desmosomes are cell-cell junctions mediating adhesion of
Externí odkaz:
https://doaj.org/article/218f18dcd14b44eabc6f22086f51cecc
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107984 (2014)
Fitting parameter sets of non-linear equations in cardiac single cell ionic models to reproduce experimental behavior is a time consuming process. The standard procedure is to adjust maximum channel conductances in ionic models to reproduce action po
Externí odkaz:
https://doaj.org/article/410f05fd9dcb494b82655b13d40ae601
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88000 (2014)
The Purkinje system is the fast conduction network of the heart which couples to the myocardium at discrete sites called Purkinje-Myocyte Junctions (PMJs). However, the distribution and number of PMJs remains elusive, as does whether a particular PMJ
Externí odkaz:
https://doaj.org/article/cbe307b662fa41be8bdbcf99e8bc9fc8
Publikováno v:
EMBC
Cardiac cellular models are utilized as the building blocks for tissue simulation. One of the imprecisions of conventional cellular modeling, especially when the models are used in tissue-level modeling, stems from the mere consideration of cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203fe2d790ab5b96fe00304f4ae41a66
https://pubmed.ncbi.nlm.nih.gov/33018511
https://pubmed.ncbi.nlm.nih.gov/33018511
Autor:
Anders Nygren, Blaise Baxter, Mahesh V Jayaraman, Noreen Kamal, Marie Williams, Frei Donald, Mayank Goyal, M. Ivan Wiggam, Emer Hopkins, Michael J. Francis, Jessalyn K. Holodinsky, Michael D. Hill
Publikováno v:
IISE Transactions on Healthcare Systems Engineering. 8:220-226
Ischemic stroke is a treatable disease with alteplase, a clot-busting medical treatment, and endovascular therapy (EVT), mechanical removal of the clot through a minimally invasive procedure. The e...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e073a2026e8f13a87796f9dd7aea3590
https://doi.org/10.1080/24725579.2018.1501623
https://doi.org/10.1080/24725579.2018.1501623
Autor:
Lucas Arantes Berg, Rodrigo Weber dos Santos, Rafael Sachetto Oliveira, Anders Nygren, Elnaz Pouranbarani
Publikováno v:
Journal of Computational Science. 53:101375
In the calibration process, replicating some cellular properties is the main focus, while the importance of membrane resistance ( R m ) that is primal in the tissue-level modeling is often underestimated. Previously, we presented a framework in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a0a5b6adaf4a96da80976424bf4ead
https://doi.org/10.1016/j.jocs.2021.101375
https://doi.org/10.1016/j.jocs.2021.101375
Autor:
Anders Nygren, Matthew S.W. Milne, Noreen Kamal, Jessalyn K. Holodinsky, Mayank Goyal, Chao Qiu, Michael D. Hill
Publikováno v:
Stroke. 48:791-794
Background and Purpose— There is uncertainty regarding the best way for patients outside of endovascular-capable or Comprehensive Stroke Centers (CSC) to access endovascular treatment for acute ischemic stroke. The role of the nonendovascular-capab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f5f73a2e9db7cbbfff6c9a18c92996
https://doi.org/10.1161/strokeaha.116.015321
https://doi.org/10.1161/strokeaha.116.015321
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225245 (2019)
PLoS ONE, Vol 14, Iss 11, p e0225245 (2019)
Mathematical models of cardiac cells have been established to broaden understanding of cardiac function. In the process of developing electrophysiological models for cardiac myocytes, precise parameter tuning is a crucial step. The membrane resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4174541403372f352e30386cd5c9594a
https://pubmed.ncbi.nlm.nih.gov/31730631
https://pubmed.ncbi.nlm.nih.gov/31730631