Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Anders, Örbom"'
Autor:
Amanda Kristiansson, Oskar Vilhelmsson Timmermand, Mohamed Altai, Sven-Erik Strand, Bo Åkerström, Anders Örbom
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Radioligand therapy with [177Lu]Lu-PSMA-617 can be used to prolong life and reduce tumor burden in terminally ill castration resistant prostate cancer patients. Still, accumulation in healthy tissue limits the activity that can be administer
Externí odkaz:
https://doaj.org/article/743ee4805dbe487dab38904bb8673f13
Autor:
Irma Mahmutovic Persson, Nina Fransén Petterson, Jian Liu, René in ‘t Zandt, Carla Carvalho, Anders Örbom, Lars E. Olsson, Karin von Wachenfeldt
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Drug-induced interstitial lung disease (ILD) is crucial to detect early to achieve the best treatment outcome. Optimally, non-invasive imaging biomarkers can be used for early detection of disease progression and treatment follow-up. Therefore, relia
Externí odkaz:
https://doaj.org/article/827e443df6da4fa3b4eb549d44709886
Autor:
Amanda Kristiansson, Oskar Vilhelmsson Timmermand, Mohamed Altai, Joanna Strand, Sven-Erik Strand, Bo Åkerström, Anders Örbom
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 731 (2022)
Prostate cancer (PC) is one of the most common malignancies affecting men, with poor prognosis after progression to metastatic castration-resistant prostate cancer (mCRPC). Radioligand therapy (RLT) targeting the overexpressed PSMA on PC cells, with,
Externí odkaz:
https://doaj.org/article/d95b91a77fca44f88b04e2e19afd0d10
Autor:
Irma Mahmutovic Persson, Hanna Falk Håkansson, Anders Örbom, Jian Liu, Karin von Wachenfeldt, Lars E. Olsson
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
A large number of systemically administered drugs have the potential to cause drug-induced interstitial lung disease (DIILD). We aim to characterize a model of DIILD in the rat and develop imaging biomarkers (IBs) for detection and quantification of
Externí odkaz:
https://doaj.org/article/514b1f1c74f4489aa6a46e8c2fb95a3e
Autor:
Amanda Kristiansson, Anders Örbom, Oskar Vilhelmsson Timmermand, Jonas Ahlstedt, Sven-Erik Strand, Bo Åkerström
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1271 (2021)
α1-Microglobulin (A1M) is an antioxidant found in all vertebrates, including humans. It has enzymatic reductase activity and can scavenge radicals and bind free heme groups. Infused recombinant A1M accumulates in the kidneys and has therefore been s
Externí odkaz:
https://doaj.org/article/57825ea6b2dc45538b608ec63215b0f4
Autor:
Amanda Kristiansson, Anders Örbom, Jonas Ahlstedt, Helena Karlsson, Wahed Zedan, Magnus Gram, Bo Åkerström, Sven-Erik Strand, Mohamed Altai, Joanna Strand, Oskar Vilhelmsson Timmermand
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 263 (2021)
Anti-prostate specific membrane antigen (PSMA) radioligand therapy is promising but not curative in castration resistant prostate cancer. One way to broaden the therapeutic index could be to administer higher doses in combination with radioprotectors
Externí odkaz:
https://doaj.org/article/0ced114b239f4017a82234fa24ba0191
Publikováno v:
Handbook of Nuclear Medicine and Molecular Imaging for Physicists ISBN: 9780429489556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb73ae631657af7e71051b75cea8835b
https://doi.org/10.1201/9780429489556-30
https://doi.org/10.1201/9780429489556-30
Autor:
Strand, Oskar Vilhelmsson Timmermand, Anders Örbom, Mohamed Altai, Wahed Zedan, Bo Holmqvist, Marcella Safi, Thuy A. Tran, Sven-Erik Strand, Joanna
Publikováno v:
Cancers; Volume 13; Issue 14; Pages: 3469
Background: The humanized monoclonal antibody (mAb) hu5A10 specifically targets and internalizes prostate cancer cells by binding to prostate specific antigen (PSA). Preclinical evaluations have shown that hu5A10 is an excellent vehicle for prostate
Autor:
Erik Larsson, Sophie E. Eriksson, Daniel L.J. Thorek, David Ulmert, Kai A Beattie, Oskar Vilhelmsson Timmermand, Bradley J. Beattie, Sven-Erik Strand, Thuy A Tran, Jörgen Elgqvist, Anders Örbom
Publikováno v:
Theranostics. 9:2129-2142
Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR) exp
Autor:
Oskar Vilhelmsson Timmermand, Anders Örbom, Mohamed Altai, Wahed Zedan, Bo Holmqvist, Marcella Safi, Thuy A. Tran, Sven-Erik Strand, Joanna Strand
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3469, p 3469 (2021)
Cancers, Vol 13, Iss 3469, p 3469 (2021)
Simple Summary The present study demonstrates that a radiolabeling strategy can positively modify hu5A10′s capacity to bind PSA and complex with the FcRn receptor, which results in a more homogenous activity distribution in tumors and enhanced ther