Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ander Estella"'
Autor:
Daniel Jericó, Karol M. Córdoba, Lei Jiang, Caroline Schmitt, María Morán, Ana Sampedro, Manuel Alegre, María Collantes, Eva Santamaría, Estíbaliz Alegre, Corinne Culerier, Ander Estella-Hermoso de Mendoza, Julen Oyarzabal, Miguel A. Martín, Iván Peñuelas, Matías A. Ávila, Laurent Gouya, Paolo G.V. Martini, Antonio Fontanellas
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 207-219 (2021)
Variegate porphyria (VP) results from haploinsufficiency of protoporphyrinogen oxidase (PPOX), the seventh enzyme in the heme synthesis pathway. There is no VP model that recapitulates the clinical manifestations of acute attacks. Combined administra
Externí odkaz:
https://doaj.org/article/f0e88f862dcd434c9fb48ea42beb448a
Autor:
Edurne San José-Enériz, Xabier Agirre, Obdulia Rabal, Amaia Vilas-Zornoza, Juan A. Sanchez-Arias, Estibaliz Miranda, Ana Ugarte, Sergio Roa, Bruno Paiva, Ander Estella-Hermoso de Mendoza, Rosa María Alvarez, Noelia Casares, Victor Segura, José I. Martín-Subero, François-Xavier Ogi, Pierre Soule, Clara M. Santiveri, Ramón Campos-Olivas, Giancarlo Castellano, Maite Garcia Fernandez de Barrena, Juan Roberto Rodriguez-Madoz, Maria José García-Barchino, Juan Jose Lasarte, Matias A Avila, Jose Angel Martinez-Climent, Julen Oyarzabal, Felipe Prosper
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Epigenetic drugs are emerging as a powerful therapeutic option for cancer treatment. Here, the authors synthesized selective chemical probes that simultaneously inhibit the G9a and DNMTs methyltransferase activity and demonstrate their anti-tumour ac
Externí odkaz:
https://doaj.org/article/286f3156e84448249eb1c05f274be064
Autor:
Jericó, Daniel, Córdoba, Karol M., Jiang, Lei, Schmitt, Caroline, Morán, María, Sampedro, Ana, Alegre, Manuel, Collantes, María, Santamaría, Eva, Alegre, Estíbaliz, Culerier, Corinne, de Mendoza, Ander Estella-Hermoso, Oyarzabal, Julen, Martín, Miguel A., Peñuelas, Iván, Ávila, Matías A., Gouya, Laurent, Martini, Paolo G.V., Fontanellas, Antonio
Publikováno v:
In Molecular Therapy - Nucleic Acids 3 September 2021 25:207-219
Autor:
Maria J. Blanco-Prieto, Miguel A. Campanero, Dolors Colomer, Joan Gil, Gaël Roué, Mercè de Frias, Janny A. Villa-Pulgarin, Ander Estella-Hermoso de Mendoza, Consuelo Gajate, Janis de la Iglesia-Vicente, Faustino Mollinedo
Supplementary Data from In vitro and In vivo Selective Antitumor Activity of Edelfosine against Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Involving Lipid Rafts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb4dc2f3d768d1429e65e103d55b907
https://doi.org/10.1158/1078-0432.22442483
https://doi.org/10.1158/1078-0432.22442483
Autor:
Maria J. Blanco-Prieto, Miguel A. Campanero, Dolors Colomer, Joan Gil, Gaël Roué, Mercè de Frias, Janny A. Villa-Pulgarin, Ander Estella-Hermoso de Mendoza, Consuelo Gajate, Janis de la Iglesia-Vicente, Faustino Mollinedo
Purpose: Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) remain B-cell malignancies with limited therapeutic options. The present study investigates the in vitro and in vivo effect of the phospholipid ether edelfosine (1-O-octadecyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1424193ed353f8009e2c4a362c09355
https://doi.org/10.1158/1078-0432.c.6519200.v1
https://doi.org/10.1158/1078-0432.c.6519200.v1
Autor:
Miguel A. Martín, Karol M. Córdoba, Antonio Fontanellas, Corinne Culerier, Eva Santamaría, Ana Sampedro, M J Morán, María Collantes, Matías A. Avila, Laurent Gouya, Manuel Alegre, Estibaliz Alegre, Caroline Schmitt, Julen Oyarzabal, Lei Jiang, Paolo Martini, Ander Estella-Hermoso de Mendoza, Iván Peñuelas, Daniel Jericó
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 207-219 (2021)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Variegate porphyria (VP) results from haploinsufficiency of protoporphyrinogen oxidase (PPOX), the seventh enzyme in the heme synthesis pathway. There is no VP model that recapitulates the clinical manifestations of acute attacks. Combined administra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07337c591a203e17f6389eba8716a73b
http://www.sciencedirect.com/science/article/pii/S2162253121001268
http://www.sciencedirect.com/science/article/pii/S2162253121001268
Autor:
Elena Sáez, Musheng Xu, Raquel Ordoñez, Amaia Vilas-Zornoza, Feifei Zhang, Xabier Agirre, Antonio Pineda-Lucena, Obdulia Rabal, Julen Oyarzabal, Felipe Prosper, Edurne San José-Enériz, Estíbaliz Miranda, Irene de Miguel, Leire Garate, Juan A. Sánchez-Arias, Ander Estella, Wei Wu
Publikováno v:
Journal of Medicinal Chemistry. 64:3392-3426
Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8ef28e03f4b1381fbbbd762da2c60a
https://doi.org/10.1021/acs.jmedchem.0c02255
https://doi.org/10.1021/acs.jmedchem.0c02255
Autor:
Obdulia, Rabal, Edurne, San José-Enériz, Xabier, Agirre, Juan Antonio, Sánchez-Arias, Irene, de Miguel, Raquel, Ordoñez, Leire, Garate, Estíbaliz, Miranda, Elena, Sáez, Amaia, Vilas-Zornoza, Antonio, Pineda-Lucena, Ander, Estella, Feifei, Zhang, Wei, Wu, Musheng, Xu, Felipe, Prosper, Julen, Oyarzabal
Publikováno v:
Journal of medicinal chemistry. 64(6)
Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bad3640d9d5cb27668dc78f6b1e780a3
https://pubmed.ncbi.nlm.nih.gov/33661013
https://pubmed.ncbi.nlm.nih.gov/33661013
Autor:
Simon Pascual-Gil, Carlos Rodríguez-Nogales, Elisa Garbayo, Ander Estella-Hermoso de Mendoza, Laura Saludas, María J. Blanco-Prieto
Publikováno v:
WIREs Nanomedicine and Nanobiotechnology. 12
Nanomedicine and drug delivery technologies play a prominent role in modern medicine, facilitating better treatments than conventional drugs. Nanomedicine is being increasingly used to develop new methods of cancer diagnosis and treatment, since this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05da04092e3f5c23a75c694ca6e11871
https://doi.org/10.1002/wnan.1637
https://doi.org/10.1002/wnan.1637
Autor:
Ana Garcia-Osta, Irene de Miguel, Carolina García-Barroso, Julen Oyarzabal, Elena Sáez, Obdulia Rabal, Marta Pérez-González, Mar Cuadrado-Tejedor, Wu Wei, Maria Espelosin, Tan Haizhong, Ana Ugarte, Ander Estella-Hermoso de Mendoza, Susana Ursua, Juan A. Sánchez-Arias, Xu Musheng
Publikováno v:
European Journal of Medicinal Chemistry. 150:506-524
We have identified chemical probes that act as dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors (>1 log unit difference versus class I HDACs) to decipher the contribution of HDAC isoforms to the positive impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc24980e1b1ca1a4a39db01fb1bf214f
https://doi.org/10.1016/j.ejmech.2018.03.005
https://doi.org/10.1016/j.ejmech.2018.03.005