Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ander Diaz Navarro"'
Autor:
Laura Escudero, Anna Llort, Alexandra Arias, Ander Diaz-Navarro, Francisco Martínez-Ricarte, Carlota Rubio-Perez, Regina Mayor, Ginevra Caratù, Elena Martínez-Sáez, Élida Vázquez-Méndez, Iván Lesende-Rodríguez, Raquel Hladun, Luis Gros, Santiago Ramón y Cajal, Maria A. Poca, Xose S. Puente, Juan Sahuquillo, Soledad Gallego, Joan Seoane
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Non-invasive and precise methods are critical for monitoring paediatric brain cancers. Here the authors show that the molecular alterations and heterogeneity of paediatric medulloblastomas can be reliably detected in circulating tumour DNA from the c
Externí odkaz:
https://doaj.org/article/c3bf556831fd4765979786b61390d38a
Autor:
Juho Kontio, Valeria Rolle Soñora, Vilma Pesola, Rijuta Lamba, Annalena Dittmann, Ander Diaz Navarro, Jarkko Koivunen, Taina Pihlajaniemi, Valerio Izzi
Publikováno v:
Scopus
The extracellular matrix (ECM) is a three-dimensional network of proteins of diverse nature, whose interactions are essential to provide tissues with the correct mechanical and biochemical cues they need for proper development and homeostasis. Change
Autor:
Binyamin A. Knisbacher, Ziao Lin, Cynthia K. Hahn, Ferran Nadeu, Martí Duran-Ferrer, Kristen E. Stevenson, Eugen Tausch, Julio Delgado, Alex Barbera-Mourelle, Amaro Taylor-Weiner, Pablo Bousquets-Muñoz, Ander Diaz-Navarro, Andrew Dunford, Shankara Anand, Helene Kretzmer, Jesus Gutierrez-Abril, Sara López-Tamargo, Stacey M. Fernandes, Clare Sun, Mariela Sivina, Laura Z. Rassenti, Christof Schneider, Shuqiang Li, Laxmi Parida, Alexander Meissner, François Aguet, Jan A. Burger, Adrian Wiestner, Thomas J. Kipps, Jennifer R. Brown, Michael Hallek, Chip Stewart, Donna S. Neuberg, José I. Martín-Subero, Xose S. Puente, Stephan Stilgenbauer, Catherine J. Wu, Elias Campo, Gad Getz
Publikováno v:
Nat Genet
Nature genetics, vol 54, iss 11
Nature Genetics
Nature genetics, vol 54, iss 11
Nature Genetics
Recent advances in cancer characterization have consistently revealed marked heterogeneity, impeding the completion of integrated molecular and clinical maps for each malignancy. Here, we focus on chronic lymphocytic leukemia (CLL), a B cell neoplasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcebcde5af0ed4f2d596ab3149447ab
https://europepmc.org/articles/PMC10084830/
https://europepmc.org/articles/PMC10084830/
Autor:
Xose S. Puente, Ana Muntañola, Ander Diaz-Navarro, José I. Martín-Subero, Blanca Espinet, Roser Vilarrasa-Blasi, Guillem Clot, Cristina López, Marta Kulis, Ferran Nadeu, Rafael Valdés-Mas, Vicente Chapaprieta, Marta Aymerich, Dolors Costa, Elias Campo, David Torrents, Sílvia Beà, Jesús Gutiérrez-Abril, Armando López-Guillermo, David Martín-García, Pedro Jares, Ralf Küppers, Eva Giné, Inmaculada Ribera-Cortada, Montserrat Puiggròs, Giancarlo Castellano, Dolors Colomer, Romina Royo, Martí Duran-Ferrer, Alba Navarro, Reiner Siebert
Publikováno v:
Blood. 136:1419-1432
Mantle cell lymphoma (MCL) is a mature B-cell neoplasm initially driven by CCND1 rearrangement with 2 molecular subtypes, conventional MCL (cMCL) and leukemic non-nodal MCL (nnMCL), that differ in their clinicobiological behavior. To identify the gen
Autor:
Anna Petit, Eva González-Suárez, Gerburg M. Wulf, Bing Zhang, Carlos Caldas, Michael T. Lewis, Joaquín Arribas, Xose S. Puente, Eva M. Trinidad, Luis Palomero, Judith Balmaña, María Teresa Soler-Monso, Marta Palafox, Lacey E. Dobrolecki, Alejandra Bruna, Suhas Vasaikar, Aleix Prat, Violeta Serra, Ander Diaz-Navarro, Jorge Gomez-Miragaya, Laia Paré, Sergi Beltran, Alejandro Collado-Sole, Purificación Muñoz, Raul Tonda, Miguel Angel Pujana, Chen Huang, Cristina Cruz
Publikováno v:
Cancer Research. 79:4258-4270
Taxanes are the mainstay of treatment in triple-negative breast cancer (TNBC), with de novo and acquired resistance limiting patient's survival. To investigate the genetic basis of docetaxel resistance in TNBC, exome sequencing was performed on match
Autor:
Ferran Nadeu, Romina Royo, Ramon Massoni-Badosa, Beatriz Garcia-Torre, Martí Duran-Ferrer, Kevin J. Dawson, Marta Kulis, Ander Diaz-Navarro, Neus Villamor, Juan L. Melero, Vicente Chapaprieta, Ana Dueso-Barroso, Julio Delgado, Riccardo Moia, Sara Ruiz-Gil, Domenica Marchese, Núria Verdaguer-Dot, Mónica Romo, Maria Rozman, Gerard Frigola, Alfredo Rivas-Delgado, Tycho Baumann, Miguel Alcoceba, Marcos González, Fina Climent, Pau Abrisqueta, Josep Castellví, Francesc Bosch, Marta Aymerich, Anna Enjuanes, Sílvia Ruiz-Gaspà, Armando López-Guillermo, Pedro Jares, Sílvia Beà, Dolors Colomer, Núria López-Bigas, Josep LlGelpí, David Torrents, Peter J. Campbell, Ivo Gut, Pablo M. Garcia-Roves, Davide Rossi, Gianluca Gaidano, Xose S. Puente, Holger Heyn, Francesco Maura, José I. Martín-Subero, Elías Campo
Publikováno v:
Cancer Research. 82:3795-3795
Introduction: Clonal evolution drives cancer development due to the emergence and/or selection of proliferatively advantageous subclones. Its understanding may facilitate the design of anticipation-based management strategies. Richter transformation
Publikováno v:
Annual review of pathology. 15
Chronic lymphocytic leukemia is a common disease in Western countries and has heterogeneous clinical behavior. The relevance of the genetic basis of the disease has come to the forefront recently, with genome-wide studies that have provided a compreh
Autor:
Anne Jouvet, Ana Gutiérrez-Fernández, Namal Abeysundara, Olivier Ayrault, Vijay Ramaswamy, Charles G. Eberhart, Jennifer A. Chan, Johan M. Kros, Xiaochong Wu, Sachin Kumar, Seung-Ki Kim, Maria C. Vladoiu, Noriyuki Kijima, Xose S. Puente, Ian F. Pollack, Robert J. Wechsler-Reya, Boleslaw Lach, Almos Klekner, Ander Diaz-Navarro, Claudia C. Faria, Lincoln Stein, Nicole Gauer, Enrique López-Aguilar, Nada Jabado, Amulya A. Nageswara Rao, Livia Garzia, David Malkin, Stefan M. Pfister, Jiannis Ragoussis, Maura Massimino, James M. Olson, Caterina Giannini, Hamza Farooq, Pim J. French, Florence M.G. Cavalli, Anna Goldenberg, John A. Calarco, Joshua B. Rubin, Maria Luisa Garrè, Betty Luu, László Bognár, Weifan Dong, Shimin Shuai, Antoine Forget, Jun Wang, Ichiyo Shibahara, Pasqualino De Antonellis, William A. Weiss, Marco A. Marra, Lola B. Chambless, Patryk Skowron, Wiesława Grajkowska, Jiao Zhang, Ali Momin, Erwin G. Van Meir, Michelle Fèvre-Montange, Rajeev Vibhakar, Ho Keung Ng, David Przelicki, Hiromichi Suzuki, Kyle Juraschka, Craig Daniels, A. Sorana Morrissy, Toshihiro Kumabe, Xi Huang, Wai Sang Poon, Swneke D. Bailey, Michael D. Taylor
Publikováno v:
Nature, 574(7780), 707-+. Nature Publishing Group
Nature
Nature, Nature Publishing Group, 2019
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature
Nature, Nature Publishing Group, 2019
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© The Author(s), under exclusive licence to Springer Nature Limited 2019
In cancer, recurrent somatic single-nucleotide variants-which are rare in most paediatric cancers-are confined largely to protein-coding genes1-3. Here we report highly re
In cancer, recurrent somatic single-nucleotide variants-which are rare in most paediatric cancers-are confined largely to protein-coding genes1-3. Here we report highly re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf69b6fedf20eee2d65c01dc77b0345b
https://pure.eur.nl/en/publications/87b8ce9e-154a-4fc3-baab-ad9bad99de72
https://pure.eur.nl/en/publications/87b8ce9e-154a-4fc3-baab-ad9bad99de72
Autor:
Lincoln Stein, Ander Diaz-Navarro, Hiromichi Suzuki, Ferran Nadeu, Julio Delgado, Xose S. Puente, Sachin Kumar, Michael D. Taylor, Elias Campo, Carlos López-Otín, Magda Pinyol, Shimin Shuai, Ana Gutiérrez-Fernández
Publikováno v:
Nature. 574(7780)
Cancers are caused by genomic alterations known as drivers. Hundreds of drivers in coding genes are known but, to date, only a handful of noncoding drivers have been discovered—despite intensive searching1,2. Attention has recently shifted to the r
Autor:
Alberto Villanueva, Miguel Angel Pujana, Conxi Lázaro, María Martínez-Iniesta, August Vidal, Gardenia Vargas-Parra, Idoia Morilla, Luis Palomero, Agostina Stradella, Anna Petit, Jordi Serra-Musach, Diana A. Puente, Eva Tornero, Teresa Soler, Gorka Ruiz de Garibay, Carmen Herranz, Francesca Mateo, Xose S. Puente, Lourdes Farre, Rafael Valdés-Mas, Ander Diaz-Navarro, Emmet McCormack
Publikováno v:
Disease Models & Mechanisms.
Understanding the mechanisms of cancer therapeutic resistance is fundamental to improving cancer care. There is clear benefit from chemotherapy in different breast cancer settings; however, knowledge of the mutations and genes that mediate resistance