Zobrazeno 1 - 10
of 148
pro vyhledávání: '"And Andrzej Dziembowski"'
Autor:
Małgorzata Rydzanicz, Bozena Kuzniewska, Marta Magnowska, Tomasz Wójtowicz, Aleksandra Stawikowska, Anna Hojka, Ewa Borsuk, Ksenia Meyza, Olga Gewartowska, Jakub Gruchota, Jacek Miłek, Patrycja Wardaszka, Izabela Chojnicka, Ludwika Kondrakiewicz, Dorota Dymkowska, Alicja Puścian, Ewelina Knapska, Andrzej Dziembowski, Rafał Płoski, Magdalena Dziembowska
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 11, Pp 2976-3004 (2024)
Abstract There is increasing evidence of mitochondrial dysfunction in autism spectrum disorders (ASD), but the causal relationships are unclear. In an ASD patient whose identical twin was unaffected, we identified a postzygotic mosaic mutation p.Q639
Externí odkaz:
https://doaj.org/article/1143eedef2364432b4464c62a2067b71
Autor:
Michał Brouze, Agnieszka Czarnocka-Cieciura, Olga Gewartowska, Monika Kusio-Kobiałka, Kamil Jachacy, Marcin Szpila, Bartosz Tarkowski, Jakub Gruchota, Paweł Krawczyk, Seweryn Mroczek, Ewa Borsuk, Andrzej Dziembowski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cytoplasmic polyadenylation plays a vital role in gametogenesis; however, the participating enzymes and substrates in mammals remain unclear. Using knockout and knock-in mouse models, we describe the essential role of four TENT5 poly(A) poly
Externí odkaz:
https://doaj.org/article/8da351a5408d442a850de28038fde70e
Autor:
Agnieszka Tudek, Paweł S. Krawczyk, Seweryn Mroczek, Rafał Tomecki, Matti Turtola, Katarzyna Matylla-Kulińska, Torben Heick Jensen, Andrzej Dziembowski
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
RNA polyadenosine tails are important for the export, translation and stability of mRNAs and play a role in non-coding RNA biogenesis. Here the authors measure yeast poly(A) tail lengths by direct RNA sequencing, revealing its dynamics in yeast exonu
Externí odkaz:
https://doaj.org/article/81fd2f0b2b364117add539bf1a1b1ef9
Autor:
Bozena Kuzniewska, Karolina Rejmak, Agata Nowacka, Magdalena Ziółkowska, Jacek Milek, Marta Magnowska, Jakub Gruchota, Olga Gewartowska, Ewa Borsuk, Ahmad Salamian, Andrzej Dziembowski, Kasia Radwanska, Magdalena Dziembowska
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
As microRNAs have emerged to be important regulators of molecular events occurring at the synapses, the new questions about their regulatory effect on the behavior have araised. In the present study, we show for the first time that the dysregulated s
Externí odkaz:
https://doaj.org/article/ce05333691984f1d9415951ca513f808
Autor:
Hélène Scheer, Caroline de Almeida, Emilie Ferrier, Quentin Simonnot, Laure Poirier, David Pflieger, François M. Sement, Sandrine Koechler, Christina Piermaria, Paweł Krawczyk, Seweryn Mroczek, Johana Chicher, Lauriane Kuhn, Andrzej Dziembowski, Philippe Hammann, Hélène Zuber, Dominique Gagliardi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
TUTase mediated uridylation of mRNA promotes degradation. Here, Scheer, de Almeida et al. show that Arabidopsis TUTase URT1 interacts directly with the translation inhibitor and decay factor DECAPPING5 and suppresses siRNA biogenesis by preventing ac
Externí odkaz:
https://doaj.org/article/d26320e63277491b9c09179e1c48bfd5
Autor:
Aleksandra Bilska, Monika Kusio-Kobiałka, Paweł S. Krawczyk, Olga Gewartowska, Bartosz Tarkowski, Kamil Kobyłecki, Dominika Nowis, Jakub Golab, Jakub Gruchota, Ewa Borsuk, Andrzej Dziembowski, Seweryn Mroczek
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Regulating polyadenylation is important for mRNA stability, which can in turn affect B cell maturation and humoral immune responses. Here the authors use Nanopore poly(A) sequencing to explore the importance of the cytoplasmic poly(A) polymerase TENT
Externí odkaz:
https://doaj.org/article/cc7369751a0649a8ac0d65c96e3806d5
Autor:
Anna Hojka-Osinska, Aleksander Chlebowski, Joanna Grochowska, Ewelina P. Owczarek, Kamila Affek, Kamila Kłosowska-Kosicka, Roman J. Szczesny, Andrzej Dziembowski
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103036- (2021)
Summary: Processive exoribonucleases are executors of RNA decay. In humans, their physical but not functional interactions were thoughtfully investigated. Here we have screened cells deficient in DIS3, XRN2, EXOSC10, DIS3L, and DIS3L2 with a custom s
Externí odkaz:
https://doaj.org/article/7875acc6df5e460a9160e947aed36e09
Autor:
Olga Gewartowska, Goretti Aranaz-Novaliches, Paweł S. Krawczyk, Seweryn Mroczek, Monika Kusio-Kobiałka, Bartosz Tarkowski, Frantisek Spoutil, Oldrich Benada, Olga Kofroňová, Piotr Szwedziak, Dominik Cysewski, Jakub Gruchota, Marcin Szpila, Aleksander Chlebowski, Radislav Sedlacek, Jan Prochazka, Andrzej Dziembowski
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109015- (2021)
Summary: Osteoblasts orchestrate bone formation through the secretion of type I collagen and other constituents of the matrix on which hydroxyapatite crystals mineralize. Here, we show that TENT5A, whose mutations were found in congenital bone diseas
Externí odkaz:
https://doaj.org/article/72264ef180444effa54deb1100b552fa
Autor:
Olga Gewartowska, Seweryn Mroczek, Goretti Aranaz Novaliches, Monika Kusio-Kobiałka, Jan Prochazka, Andrzej Dziembowski
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100344- (2020)
Externí odkaz:
https://doaj.org/article/068a149ed5904d3291f585e6999a1cf7
Autor:
Adam Pyzik, Martyna Ciezkowska, Pawel S. Krawczyk, Adam Sobczak, Lukasz Drewniak, Andrzej Dziembowski, Leszek Lipinski
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-16 (2018)
Abstract Background Although interactions between microorganisms involved in biogas production are largely uncharted, it is commonly accepted that methanogenic Archaea are essential for the process. Methanogens thrive in various environments, but the
Externí odkaz:
https://doaj.org/article/7bfb9873d4444bbebb495157ad74f185