Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ancilla Neu"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance In eukoryotes, 3′ to 5′ mRNA degradation is a major pathway to reduce mRNA levels and, thus, an important means to regulate gene expression. Herein, messenger RNA (mRNA) is hydrolyzed from the 3′ end by the exosome complex, produci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1772b4a5634a9afec2ae5f183e264e8
http://europepmc.org/articles/PMC7431086
http://europepmc.org/articles/PMC7431086
Autor:
Emily Eilbert, Lisa Yasmin Asseck, Christopher Grefen, Melanie Hildebrandt, Daniel Slane, Patrick Bürgel, Kai Wang, Martin Bayer, Ancilla Neu, Wolfgang Lukowitz, Martina Kolb, Agnes Henschen, Thomas J. Musielak
In flowering plants, the asymmetrical division of the zygote is the first hallmark of apical-basal polarity of the embryo and is controlled by a MAP kinase pathway that includes the MAPKKK YODA (YDA). In Arabidopsis, YDA is activated by the membrane-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ed223039df40199650ab548691edcd
https://europepmc.org/articles/PMC6431185/
https://europepmc.org/articles/PMC6431185/
Publikováno v:
RNA. 22:1454-1466
The eukaryotic mRNA 5′ cap structure is indispensible for pre-mRNA processing, mRNA export, translation initiation, and mRNA stability. Despite this importance, structural and biophysical studies that involve capped RNA are challenging and rare due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb41496f6cf0b390ea6ccd8cfd901da
https://doi.org/10.1261/rna.056614.116
https://doi.org/10.1261/rna.056614.116
Autor:
Mira Krendel, Remco Sprangers, Ancilla Neu, Ralph T. Böttcher, Saranya P. Wyles, Jan M. van Deursen, Huihuang Yan, Sindhuja Sominidi-Damodaran, Ditte Marie Saunte, Jeong Heon Lee, Jann N. Sarkaria, Jørgen Lock-Andersen, Nille Behrendt, Ekaterina Nikolova, Krutika S. Gaonkar, Tamas Ordog, Thilo Stehle, Alexander Meves, Edwin J. Squirewell, Joel B. Heim, Georg Zocher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences USA, 114, 3933-3938
Proceedings of the National Academy of Sciences USA, 114, 15, pp. 3933-3938
Proceedings of the National Academy of Sciences USA, 114, 3933-3938
Proceedings of the National Academy of Sciences USA, 114, 15, pp. 3933-3938
Item does not contain fulltext Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase involved in development and human disease, including cancer. It is currently thought that the four-point one, ezrin, radixin, moesin (FERM)-kinase domain link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8913bb93f566b1fa9b01f59173e6a779
https://hdl.handle.net/11858/00-001M-0000-002D-540B-111858/00-001M-0000-002D-540C-011858/00-001M-0000-002D-540A-311858/00-001M-0000-002D-53F7-611858/00-001M-0000-002D-53F9-211858/00-001M-0000-002D-540D-E
https://hdl.handle.net/11858/00-001M-0000-002D-540B-111858/00-001M-0000-002D-540C-011858/00-001M-0000-002D-540A-311858/00-001M-0000-002D-53F7-611858/00-001M-0000-002D-53F9-211858/00-001M-0000-002D-540D-E
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie-International Edition, 53(28), 7354-7359. WILEY-V C H VERLAG GMBH
Angewandte Chemie-International Edition, 53(28), 7354-7359. WILEY-V C H VERLAG GMBH
In eukaryotic cells, components of the 5' to 3' mRNA degradation machinery can undergo a rapid phase transition. The resulting cytoplasmic foci are referred to as processing bodies (P-bodies). The molecular details of the self-aggregation process are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6177313d565322a337e922bae27b9ccc
https://doi.org/10.1002/anie.201402885
https://doi.org/10.1002/anie.201402885
Publikováno v:
Angewandte Chemie. 126:7482-7487
In eukaryotischen Zellen konnen die Komponenten des 5′-3′-Abbaumechanismus der Boten-RNA (mRNA) einen schnellen Phasenubergang durchlaufen. Die resultierenden zytoplasmatischen Zentren werden Processing Bodys (P-bodys) genannt. Allerdings sind di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0acbf5b1b5563dd3d5caed2eed4d3700
https://doi.org/10.1002/ange.201402885
https://doi.org/10.1002/ange.201402885
Autor:
Friedrich Götz, Gottfried Unden, Thilo Stehle, Volker Niemann, Ancilla Neu, Stephanie Nilkens, Mareike Koch-Singenstreu
Publikováno v:
Journal of Molecular Biology. 426:1539-1553
Staphylococci are able to use nitrate as an alternative electron acceptor during anaerobic respiration. The regulation of energy metabolism is dependent on the presence of oxygen and nitrate. Under anaerobic conditions, staphylococci employ the nitra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83d2fbc823d91ca1f373d80ad1d8186
https://doi.org/10.1016/j.jmb.2013.12.026
https://doi.org/10.1016/j.jmb.2013.12.026
Publikováno v:
Nature chemical biology
The scavenger decapping enzyme hydrolyzes the protective 5' cap structure on short mRNA fragments that are generated from the exosomal degradation of mRNAs. From static crystal structures and NMR data, it is apparent that the dimeric enzyme has to un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb24a5ab97c80a0fb72303be611bac3
https://pubmed.ncbi.nlm.nih.gov/26258763
https://pubmed.ncbi.nlm.nih.gov/26258763
Publikováno v:
Journal of molecular biology. 414(2)
The nuclear LSm2–8 ( l ike Sm ) complex and the cytoplasmic LSm1–7 complex play a central role in mRNA splicing and degradation, respectively. The LSm proteins are related to the spliceosomal Sm proteins that form a heteroheptameric ring around s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47f81a1659ab4127df4355a03a35f04
https://pubmed.ncbi.nlm.nih.gov/22001694
https://pubmed.ncbi.nlm.nih.gov/22001694