Zobrazeno 1 - 10
of 1 582
pro vyhledávání: '"Anchorage-Independent Growth"'
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32626- (2024)
It is well-known that the survival of metastatic cells during their dissemination plays an important role in metastasis. However, does this mean that the final result of the metastatic cascade (the volume of metastatic damage to distant organs and ti
Externí odkaz:
https://doaj.org/article/9f65225b079d464c9be6064ca91dc4d3
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9572 (2024)
The epithelial–mesenchymal transition (EMT) phenotype, identified as a significant clinical indicator in regard to cancer, manifests as a biological process wherein cells transition from having epithelial to mesenchymal characteristics. Physiologic
Externí odkaz:
https://doaj.org/article/57de20ff52f240e693e03bb1bd5d7db9
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The main known function of Nudix hydrolase 2 (Nudt2) is to hydrolyze the secondary messenger diadenosine 5’, 5’’’-p1, p4-tetraphosphate (Ap4A). In this study we examined the role of Nudt2 in breast carcinoma through its expression in human in
Externí odkaz:
https://doaj.org/article/830bf0a3f4714809ac310c98574ffbc0
Autor:
Rungroch Sungthong, Hnin Ei Ei Khine, Somruethai Sumkhemthong, Pithi Chanvorachote, Rossarin Tansawat, Chatchai Chaotham
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-12 (2023)
Abstract Background Malignant cells adopt anoikis resistance to survive anchorage-free stresses and initiate cancer metastasis. It is still unknown how varying periods of anchorage loss contribute to anoikis resistance, cell migration, and metabolic
Externí odkaz:
https://doaj.org/article/b4c27435e34f4a1b9ba3b7a42a770f56
Akademický článek
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Autor:
Wuxiyar Otkur, Xiaolong Liu, Huan Chen, Siyi Li, Ting Ling, Hanchen Lin, Renyu Yang, Tian Xia, Huan Qi, Hai-Long Piao
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and purpose: GPR35, a member of the orphan G-protein-coupled receptor, was recently implicated in colorectal cancer (CRC). However, whether targeting GPR35 by antagonists can inhibit its pro-cancer role has yet to be answered.Experimental
Externí odkaz:
https://doaj.org/article/d8d3f62a5eab4ece9a2bdea4fa48593b
Autor:
Pang-Ting Cheng, Yu-Chiao Cheng, Muhammet Oner, Yu-Hsuan Li, Mei-Chih Chen, Jyh-Horng Wu, Ting-Chieh Chang, Ayse Celik, Fang-Ling Liu, Hsin-Yi Wang, Chih-Ho Lai, Jer-Tsong Hsieh, Chieh-Yin Chen, Ho Lin
Publikováno v:
Chinese Journal of Physiology, Vol 65, Iss 4, Pp 209-214 (2022)
Antrodia salmonea (AS) is a fungus, which belongs to a fungal family of Taiwanofungus salmoneus with the features of anti-oxidant, anti-inflammatory, and anticancer. Recent studies have shown that AS has anti-cancer functions in ovarian and breast ca
Externí odkaz:
https://doaj.org/article/10647a3d90e341e68778cd9a34dc5d48
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10513 (2023)
Nudt2 encodes a diadenosine tetraphosphate (Ap4A) hydrolase that catalyzes the hydrolysis of Ap4A and is involved in the lysyl tRNA synthetase-Ap4A-Nudt2 (LysRS-Ap4A-Nudt2) signaling pathway. We have previously demonstrated that this pathway is activ
Externí odkaz:
https://doaj.org/article/58820327e45e45a3952c0659a1941200