Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anchisa Poonprasartporn"'
Autor:
Anchisa Poonprasartporn1 anchisa@scphc.ac.th, Piyamaporn Uttaranakorn1, Raweewan Chuaybamroong1
Publikováno v:
Thai Journal of Pharmaceutical Sciences. 2023, Vol. 47 Issue 4, p1-11. 11p.
Publikováno v:
Poonprasartporn, A & Chan, K L A 2022, ' Label-free study of intracellular glycogen level in Metformin and Resveratrol-treated insulin-resistant HepG2 by live-cell FTIR spectroscopy ', Biosensors and Bioelectronics, vol. 212, 114416 . https://doi.org/10.1016/j.bios.2022.114416
Conventional in vitro study often involves the destruction of the cells followed by purification and dilution steps before applying enzymatic assay or metabolomic analysis. It is a costly and laborious process, and it cannot monitor changes as a func
Publikováno v:
SSRN Electronic Journal.
Autor:
K. L. Andrew Chan, Anchisa Poonprasartporn, Wachirun Terakosolphan, Richard D. Harvey, Ben Forbes, Ali Altharawi
Publikováno v:
International Journal of Pharmaceutics. 609:121118
The quantification of drug in living cells is of increasing interest in pharmaceutical research because of its importance in understanding drug efficacy and toxicity. Label-free in situ measurement methods are advantageous for their ability to obtain
Publikováno v:
Poonprasartporn, A & Andrew Chan, K L 2021, ' Live cell ATR-FTIR spectroscopy as a novel bioanalytical tool for cell glucose metabolism research ', Biochimica et biophysica acta-Molecular cell research, vol. 1868, no. 7, 119024, pp. 119024 . https://doi.org/10.1016/j.bbamcr.2021.119024
Current novel drug developments for the treatment of diabetes require multiple bioanalytical assays to interrogate the cellular metabolism, which are costly, laborious and time-consuming. Fourier-transform infrared (FTIR) spectroscopy is a nondestruc