Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anchalee Jaidee"'
Autor:
Shalini Nair, Becky Miller, Marion Barends, Anchalee Jaidee, Jigar Patel, Mayfong Mayxay, Paul Newton, François Nosten, Michael T Ferdig, Tim J C Anderson
Publikováno v:
PLoS Genetics, Vol 4, Iss 10, p e1000243 (2008)
Copy number polymorphism (CNP) is ubiquitous in eukaryotic genomes, but the degree to which this reflects the action of positive selection is poorly understood. The first gene in the Plasmodium folate biosynthesis pathway, GTP-cyclohydrolase I (gch1)
Externí odkaz:
https://doaj.org/article/efb60e45de6c415c8fc2f41919cdac8a
Autor:
Denae Nash, Shalini Nair, Anne-Catrin Uhlemann, François Nosten, Tim J. Anderson, Marion Barends, Daniel Sudimack, Sanjeev Krishna, Anchalee Jaidee
When selection is strong and beneficial alleles have a single origin, local reductions in genetic diversity are expected. However, when beneficial alleles have multiple origins or were segregating in the population prior to a change in selection regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e5d697832433e29e4888d32a34e68e
https://ora.ox.ac.uk/objects/uuid:fb574c07-adc7-4ac4-bfc8-cb1a0aeb02eb
https://ora.ox.ac.uk/objects/uuid:fb574c07-adc7-4ac4-bfc8-cb1a0aeb02eb
Autor:
Nicholas J. White, Bruce Russell, Nicholas P. J. Day, Zbynek Bozdech, Lei Zhu, Sachel Mok, Anchalee Jaidee, Peter R. Preiser, Mallika Imwong, François Nosten
Publikováno v:
Scientific Reports
Historically seen as a benign disease, it is now becoming clear that Plasmodium vivax can cause significant morbidity. Effective control strategies targeting P. vivax malaria is hindered by our limited understanding of vivax biology. Here we establis
Autor:
Bruce Russell, Mallika Imwong, Hagai Ginsburg, Nicholas J. White, Guangan Hu, Zbynek Bozdech, Sachel Mok, Jane M. Carlton, François Nosten, Peter R. Preiser, Nicholas P. J. Day, Anchalee Jaidee
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16290-16295
Plasmodium vivax causes over 100 million clinical infections each year. Primarily because of the lack of a suitable culture system, our understanding of the biology of this parasite lags significantly behind that of the more deadly species P. falcipa
Autor:
Tim J. Anderson, Alan Brockman, Dan Sudimack, Shalini Nair, Paul N. Newton, Anchalee Jaidee, Rattanaxay Phetsouvanh, Nicholas J. White, Samlane Phompida, Marion Barends, Mayfong Mayxay, Tiengkham Pongvongsa
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 76:245-250
Recent drug trials in Laos have shown high levels of Plasmodium falciparum resistance to chloroquine, but there are no published data on in vitro antimalarial drug susceptibility. We used the double-site enzyme-linked pLDH immunodetection (DELI) assa
Autor:
Tim J. Anderson, François Nosten, Daniel Sudimack, Jeff T. Williams, Anchalee Jaidee, Shalini Nair, Ric N. Price, Marion Barends
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences
Malaria parasites vary in phenotypic traits of biomedical or biological interest such as growth rate, virulence, sex ratio and drug resistance, and there is considerable interest in identifying the genes that underlie this variation. An important fir
Autor:
Laurent Rénia, Aung Pyae Phyo, Rossarin Suwanarusk, Mara L. Leimanis, François Nosten, Supaporn Kaewpongsri, Marion Barends, Anchalee Jaidee, Kanlaya Sriprawat, Bruce Russell
The novel organometallic chloroquine analog ferroquine (SSR 97193) is effective against chloroquine-resistant Plasmodium falciparum . The ex vivo efficacy of ferroquine against Plasmodium vivax isolates was tested. Ferroquine has a potent ex vivo eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20970cb59c1b970e383398b110c6ab2
https://europepmc.org/articles/PMC2863649/
https://europepmc.org/articles/PMC2863649/
Autor:
Marion Barends, Enny Kenangalem, Bruce Russell, Budi Prasetyorini, François Nosten, Richard N. Price, Emiliana Tjitra, Qin Cheng, Rossarin Suwanarusk, Marina Chavchich, Usa Lek-Uthai, Anchalee Jaidee, Kim A. Piera, Nicholas M. Anstey, Ferryanto Chalfein
Publikováno v:
The Journal of infectious diseases. 198(10)
Malaria continues to exert a huge global burden both in public health and economic terms. Although Plasmodium falciparum infections have been the focus of research and control efforts, there is a growing awareness that the burden of, and morbidity an
Autor:
Michael D. Edstein, Ric N. Price, Usa Lek-Uthai, François Nosten, Thomas Travers, Wesley W Sharrock, Kanlaya Sriprawat, Anchalee Jaidee, Bruce Russell, Varakorn Kosaisavee, Rossarin Suwanarusk
Publikováno v:
Malaria Journal, Vol 7, Iss 1, p 94 (2008)
Malaria Journal
Malaria Journal
Background Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium
Publikováno v:
Malaria Journal
Malaria Journal, Vol 6, Iss 1, p 81 (2007)
Malaria Journal, Vol 6, Iss 1, p 81 (2007)
Background On the borders of Thailand, Plasmodium falciparum has become resistant to nearly all available drugs, and there is an urgent need to find new antimalarial drugs or drug combinations. Ferroquine (SSR97193) is a new 4-aminoquinoline antimala