Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Anca Milea"'
Autor:
Ramlogan Sowamber, Rania Chehade, Mahmoud Bitar, Leah V. Dodds, Anca Milea, Brian Slomovitz, Patricia A. Shaw, Sophia H.L. George
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 261-274 (2019)
Background: CCAAT/enhancer binding protein delta (C/EBPδ,CEBPD), a gene part of the highly conserved basic-leucine zipper (b-ZIP) domain of transcriptional factors, is downregulated in 65% of high grade serous carcinomas of the ovary (HGSC). Overexp
Externí odkaz:
https://doaj.org/article/0989b79b92c348a89dcc100eaa78ca44
Autor:
Leah V. Dodds, Alex P Sanchez-Covarrubias, Ramlogan Sowamber, Anca Milea, Andre Pinto, Yuguang Ban, Matthew Schlumbrecht, Patricia A Shaw, Sophia HL George
SummaryER and PR regulate growth and differentiation in normal ovaries and fallopian tubes and in HGSC transformation and progression. Higher PR expression was associated with improved survival outcomes, while high ER expression was associated with w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f2cdc65d403d9518e89d87c77afeea7
https://doi.org/10.1101/2023.04.21.23288934
https://doi.org/10.1101/2023.04.21.23288934
PDF file, 957K, Spectrum output algorithm showing annotations made to include the interleukocyte population in normal FTE and intratumor leukocyte population in both STICs and HGSC where yellow, orange and red represent positively stained cells and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bb75150fec81fa0fc7d208652be750
https://doi.org/10.1158/1078-0432.22447020
https://doi.org/10.1158/1078-0432.22447020
PDF file, 597K, A. Demonstration of immunohistochemical analyses of the Ki67 stain was performed by 2 independent observers (blinded), where 0 < 1%, 1= 1%, 2=2 - 4%, 3=5 - 15% and 4> 4%. B. Distribution of Ki67 scores, by independent observers betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3f3ac6d33386ff2b4839022fa4a15f
https://doi.org/10.1158/1078-0432.22447026
https://doi.org/10.1158/1078-0432.22447026
PDF file, 209K, List of significant GO biological process terms highly represented when comparing FTE-BRCA1 to FTE-nonBRCA transcriptome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38da97638065b4520bba8df741b16aa6
https://doi.org/10.1158/1078-0432.22447017
https://doi.org/10.1158/1078-0432.22447017
Autor:
Owen A. O'Connor, Yaping Shou, Kathleen Roberge, Anca Milea, Eric L. Sievers, Robert A. Uger, Penka S. Petrova, Tina Catalano, Lisa D.S. Johnson, Oleg E. Akilov, Christiane Querfeld, Kerry J. Savage, Jasmine Zain, Matthew G. Mei, Steven M. Horwitz, James M. Foran, Anjali S. Advani, Mary-Elizabeth M. Percival, Diego Villa, Mark D. Minden, Ahmed Sawas, Ian W. Flinn, Robert W. Chen, Alexander M. Lesokhin, Michael B. Maris, Stephen M. Ansell
Study Schema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281c50bb0e69ede50363e21f4afa6737
https://doi.org/10.1158/1078-0432.22482851.v1
https://doi.org/10.1158/1078-0432.22482851.v1
Autor:
Owen A. O'Connor, Yaping Shou, Kathleen Roberge, Anca Milea, Eric L. Sievers, Robert A. Uger, Penka S. Petrova, Tina Catalano, Lisa D.S. Johnson, Oleg E. Akilov, Christiane Querfeld, Kerry J. Savage, Jasmine Zain, Matthew G. Mei, Steven M. Horwitz, James M. Foran, Anjali S. Advani, Mary-Elizabeth M. Percival, Diego Villa, Mark D. Minden, Ahmed Sawas, Ian W. Flinn, Robert W. Chen, Alexander M. Lesokhin, Michael B. Maris, Stephen M. Ansell
Purpose:TTI-621 (SIRPα-IgG1 Fc) is a novel checkpoint inhibitor that activates antitumor activity by blocking the CD47 “don't eat me” signal. This first-in-human phase I study (NCT02663518) evaluated the safety and activity of TTI-621 in relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6229d70998f979096284ba3849db926
https://doi.org/10.1158/1078-0432.c.6531017
https://doi.org/10.1158/1078-0432.c.6531017
Purpose: Women who have inherited germline mutations of BRCA1/BRCA2 are at increased risk of developing high-grade serous carcinoma, and many of these cancers arise in the distal fimbriated end of the fallopian tube. We have previously shown that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ac5e0cfc31611b5e049a96401a62f3
https://doi.org/10.1158/1078-0432.c.6520950.v1
https://doi.org/10.1158/1078-0432.c.6520950.v1
PDF file, 634K, Distribution of Ki67+ cells in histological normal FTE based on age. There was no statistical difference looking at ranges 45, 50 or 55 years of age as a cutoff for initiation of menopause.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac6e218b506ad1807017fe13220884e
https://doi.org/10.1158/1078-0432.22447023.v1
https://doi.org/10.1158/1078-0432.22447023.v1
Autor:
Leah Dodds, Anca Milea, Mahmoud Bitar, Brian M. Slomovitz, Rania Chehade, Patricia Shaw, Ramlogan Sowamber, Sophia George
Publikováno v:
EBioMedicine. 44:261-274
Background CCAAT/enhancer binding protein delta (C/EBPδ,CEBPD), a gene part of the highly conserved basic-leucine zipper (b-ZIP) domain of transcriptional factors, is downregulated in 65% of high grade serous carcinomas of the ovary (HGSC). Overexpr