Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anca M. Pasca"'
Autor:
Hemmen Sabir, Elke Maes, Margit Zweyer, Yvonne Schleehuber, Farhad B. Imam, Jared Silverman, Yasmine White, Raymand Pang, Anca M. Pasca, Nicola J. Robertson, Emin Maltepe, Maria E. Bernis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Intrapartum hypoxia–ischemia leading to neonatal encephalopathy (NE) results in significant neonatal mortality and morbidity worldwide, with > 85% of cases occurring in low- and middle-income countries (LMIC). Therapeutic hypothermia (HT)
Externí odkaz:
https://doaj.org/article/0b4133575d944984a9e37a8a0281e7e8
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Immature gastrointestinal motility impedes preterm infant survival. The enteric nervous system controls gastrointestinal motility, yet it is unknown when the human enteric nervous system matures enough to carry out vital functions. Here we d
Externí odkaz:
https://doaj.org/article/bbc103a14dc04394b9d18b09ebe71b49
Autor:
Wojciech P. Michno, Alyssa Puno, Li Li, Amanda Everitt, Kate McCluskey, Fikri Birey, Saw Htun, Dhriti Nagar, Yuqin Dai, Emily Gurwitz, A. Jeremy Willsey, Anca M. Pasca
SUMMARYExtremely preterm born individuals at < 28 postconceptional weeks (PCW) are at high risk for encephalopathy of prematurity and life-long neuropsychiatric conditions. Clinical studies and animal models of preterm brain injury suggest that encep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac26a058eb1bb152677037bd0eb68a32
https://doi.org/10.1101/2023.05.01.538334
https://doi.org/10.1101/2023.05.01.538334
Autor:
Alyssa Puno, Fangfei Qu, Angus Toland, Dian Yang, Anca M. Pasca, Wojciech Michno, Myung Chang Lee, Millie Das, Siqi Cao, Chioma J. Madubata, Christina S. Kong, Monte M. Winslow, Alexandros P. Drainas, Julien Sage
Brain metastasis is a major cause of morbidity and mortality in cancer patients. Here we investigated mechanisms allowing small-cell lung cancer (SCLC) cells to grow in the brain. We show that SCLC cells undergo a cell state transition towards neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c6e6ea68d898f0c54ea831773c5269
https://doi.org/10.1101/2021.08.10.455426
https://doi.org/10.1101/2021.08.10.455426
Autor:
Jonathan D. Reiss, Laura S. Peterson, Sophia N. Nesamoney, Alan L. Chang, Anca M. Pasca, Ivana Marić, Gary M. Shaw, Brice Gaudilliere, Ronald J. Wong, Karl G. Sylvester, Sonia L. Bonifacio, Nima Aghaeepour, Ronald S. Gibbs, David K. Stevenson
Publikováno v:
Experimental neurology. 351
Preterm newborns are exposed to several risk factors for developing brain injury. Clinical studies have suggested that the presence of intrauterine infection is a consistent risk factor for preterm birth and white matter injury. Animal models have co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91cbdbb813f568974ee79a5b2f62aac
https://pubmed.ncbi.nlm.nih.gov/35081400
https://pubmed.ncbi.nlm.nih.gov/35081400
Autor:
Alfredo M. Valencia, Daniel H. Geschwind, Min-Yin Li, Fikri Birey, Aaron Gordon, Sergiu P. Paşca, Omer Revah, Anca M. Pasca, Mayuri Vijay Thete
SUMMARYDefects in interneuron migration during forebrain development can disrupt the assembly of cortical circuits and have been associated with neuropsychiatric disease. The molecular and cellular bases of such deficits have been particularly diffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1fc6d8ed85f1deb5fba3b09b14e262
https://doi.org/10.1101/2021.06.14.448277
https://doi.org/10.1101/2021.06.14.448277
Autor:
Arwa Kathiria, Alexandro E. Trevino, Howard Y. Chang, Laksshman Sundaram, Sergiu P. Paşca, Anshul Kundaje, Anca M. Pasca, Kyle Kai-How Farh, Anna Shcherbina, William J. Greenleaf, Jimena Andersen, Fabian Müller
Genetic perturbations of cerebral cortical development can lead to neurodevelopmental disease, including autism spectrum disorder (ASD). To identify genomic regions crucial to corticogenesis, we mapped the activity of gene-regulatory elements generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ec07061a251c1b51e9c34720360a62
https://doi.org/10.1101/2020.12.29.424636
https://doi.org/10.1101/2020.12.29.424636
Publikováno v:
Journal of Thoracic Oncology. 15:S34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e93c41c7080dd28d1b9e67f376404e1
https://doi.org/10.1016/j.jtho.2019.12.089
https://doi.org/10.1016/j.jtho.2019.12.089
Autor:
Anca M. Pasca, Anna A. Penn
Publikováno v:
NeoReviews. 11:e64-e77
The placenta long has been underappreciated and understudied by the scientific community. Improper function of this critical organ causes fetal abnormalities, preterm labor, and the most common disease of pregnancy, preeclampsia. Despite the importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4912b197a66ee5f48d731aaefe948b9d
https://doi.org/10.1542/neo.11-2-e64
https://doi.org/10.1542/neo.11-2-e64
Autor:
Chul Hoon Kim, Christopher D. Makinson, Yuan Tian, John R. Huguenard, Anca M. Pasca, Nina Huber, Steven A. Sloan, Jin-Young Park, Sergiu P. Paşca, Stephen J. Smith, Ben A. Barres, Nancy A. O'Rourke, Khoa D. Nguyen, Daniel H. Geschwind, Laura E. Clarke
Publikováno v:
Nature methods, vol 12, iss 7
The human cerebral cortex develops through an elaborate succession of cellular events that, when disrupted, can lead to neuropsychiatric disease. The ability to reprogram somatic cells into pluripotent cells that can be differentiated in vitro provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e88f244adfc9ebe1d65ef10c4492b2b
https://europepmc.org/articles/PMC4489980/
https://europepmc.org/articles/PMC4489980/