Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Anca Chelariu-Raicu"'
Autor:
Anca Chelariu-Raicu, Sarina A. Piha-Paul, Mariana Chavez-MacGregor, Jason Johnson, Raymond Sawaya, Mary Frances McAleer, Alissa Nguyen, Audrey Hartnett, Apostolia M. Tsimberidou, Funda Meric-Bernstam, Ecaterina E. Dumbrava
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 6, Iss 3, Pp 158-161 (2023)
Poly (adenosine diphosphate-ribose) polymerase inhibitors (PARP)i are emerging as standard oncology treatments in various tumor types. The indications will expand as PARPi are being investigated in various breast cancer subtypes. Currently, except fo
Externí odkaz:
https://doaj.org/article/545f86fe16e24768a57c93689e01ab61
Autor:
Christopher J. LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S. Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K. Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B. Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J. Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K. Sood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Antiangiogenic treatment targeting the vascular endothelial growth factor (VEGF) pathway is a powerful tool to combat tumor growth and progression; however, drug resistance frequently emerges. We identify CD5L (CD5 antigen-like precursor) as
Externí odkaz:
https://doaj.org/article/a4cffeff90ca418b8ed9c213a7bf3531
Autor:
Marie Forster, Rachel Wuerstlein, Alexander Koenig, Alexandra Stefan, Elisa Wiegershausen, Falk Batz, Fabian Trillsch, Sven Mahner, Nadia Harbeck, Anca Chelariu-Raicu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSafety and tolerability of COVID-19 vaccines were demonstrated by several clinical trials which led to the first FDA/EMA approvals in 2021. Because of mass immunizations, most social restrictions were waived with effects on quality of lif
Externí odkaz:
https://doaj.org/article/4fc60298fce04429b70cba15f75c3b04
Autor:
Fabian B. T. Kraus, Elena Sultova, Kathrin Heinrich, Andreas Jung, C. Benedikt Westphalen, Christina V. Tauber, Jörg Kumbrink, Martina Rudelius, Frederick Klauschen, Philipp A. Greif, Alexander König, Anca Chelariu-Raicu, Bastian Czogalla, Alexander Burges, Sven Mahner, Rachel Wuerstlein, Fabian Trillsch
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2345 (2024)
Advances in molecular tumor diagnostics have transformed cancer care. However, it remains unclear whether precision oncology has the same impact and transformative nature across all malignancies. We conducted a retrospective analysis of patients with
Externí odkaz:
https://doaj.org/article/bef91cea36b9475bbf8817dfe82ed9cb
Autor:
Yunfei Wen, Anca Chelariu-Raicu, Sujanitha Umamaheswaran, Alpa M. Nick, Elaine Stur, Pahul Hanjra, Dahai Jiang, Nicholas B. Jennings, Xiuhui Chen, Sara Corvigno, Deanna Glassman, Gabriel Lopez-Berestein, Jinsong Liu, Mien-Chie Hung, Anil K. Sood
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112154- (2023)
Externí odkaz:
https://doaj.org/article/86f0eca327d4447fa688f6ac48d23946
Autor:
Susann Badmann, Doris Mayr, Elisa Schmoeckel, Anna Hester, Christina Buschmann, Susanne Beyer, Thomas Kolben, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In recurrent epithelial ovarian cancer (EOC) most patients develop platinum-resistance. On molecular level the NRF2 pathway, a cellular defense mechanism against reactive oxygen species, is induced. In this study, we investigate AKR1C1/2, ta
Externí odkaz:
https://doaj.org/article/51dfe0d42da94dd1b154d81478a61c37
Autor:
Marie Forster, Rachel Wuerstlein, Alexander Koenig, Niklas Amann, Susanne Beyer, Till Kaltofen, Tom Degenhardt, Alexander Burges, Fabian Trillsch, Sven Mahner, Nadia Harbeck, Anca Chelariu-Raicu
Publikováno v:
Breast, Vol 60, Iss , Pp 214-222 (2021)
Introduction: The side effects of systemic cancer therapy and the lack of clinical data on safety and efficacy of COVID-19 vaccination in cancer patients cause uncertainty among the patients about whether to get vaccinated or not. Here, we evaluated
Externí odkaz:
https://doaj.org/article/c56b223aaf9545459022a504855c2e26
Autor:
Yunfei Wen, Anca Chelariu-Raicu, Sujanitha Umamaheswaran, Alpa M. Nick, Elaine Stur, Pahul Hanjra, Dahai Jiang, Nicholas B. Jennings, Xiuhui Chen, Sara Corvigno, Deanna Glassman, Gabriel Lopez-Berestein, Jinsong Liu, Mien-Chie Hung, Anil K. Sood
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110301- (2022)
Summary: Anti-angiogenic therapies, such as anti-VEGF antibodies (AVAs), have shown promise in clinical settings. However, adaptive resistance to such therapies occurs frequently. We use orthotopic ovarian cancer models with AVA-adaptive resistance t
Externí odkaz:
https://doaj.org/article/d56e8ff2f87f4a398192d9812e8a3e98
Autor:
Nicole Elisabeth Topalov, Doris Mayr, Clemens Scherer, Anca Chelariu-Raicu, Susanne Beyer, Anna Hester, Fabian Kraus, Mingjun Zheng, Till Kaltofen, Thomas Kolben, Alexander Burges, Sven Mahner, Fabian Trillsch, Udo Jeschke, Bastian Czogalla
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The impact of Actin beta-like 2 (ACTBL2), a novel described actin isoform, on epithelial ovarian cancer (EOC) biology has not been investigated so far. In this study, we analyzed the prognostic and functional significance of ACTBL2 and its regulatory
Externí odkaz:
https://doaj.org/article/a8ab4bea62a044918dd18ca46829d427
Autor:
Zhi Ma, Huixia Yang, Lin Peng, Christina Kuhn, Anca Chelariu-Raicu, Sven Mahner, Udo Jeschke, Viktoria von Schönfeldt
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundLewis antigens such as Sialyl Lewis A (sLeA), Sialyl Lewis X (sLeX), Lewis X (LeX), and Lewis Y (LeY) are a class of carbohydrate molecules that are known to mediate adhesion between tumor cells and endothelium by interacting with its selec
Externí odkaz:
https://doaj.org/article/8300ea3fc4e244359f24f7ab94b2e660