Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anbu Karani Adikesavan"'
Autor:
Ilya B. Novikov, Tajhal Dayaram, Neha Parikh, Griff Weber, Angela D. Wilkins, Scott Spangler, Sam Regenbogen, Ying Chen, Linda Kato, Ana Lelescu, Shenghua Bao, Benjamin J. Bachman, Byung-Kwon Choi, Houyin Zhang, Anbu Karani Adikesavan, Curtis R. Pickering, Lawrence A. Donehower, Meena Nagarajan, Christie M. Buchovecky, Kenneth L. Scott, Jacques L. Labrie, Olivier Lichtarge, Sung Yun Jung, Peter J. Haas, Stephen K. Boyer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We adapted natural language processing to the biological literature and demonstrated end-to-end automated knowledge discovery by exploring subtle word connections. General text mining scanned 21 million publication abstracts and selected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d9a167c44ea6895d38cb1e4365a2af
https://doi.org/10.1073/pnas.1806643115
https://doi.org/10.1073/pnas.1806643115
Publikováno v:
Chemico-biological interactions. 294
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Office of Integrity of the University o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7dd0c63afe5aa542dbaa16d485166321
https://pubmed.ncbi.nlm.nih.gov/16806134
https://pubmed.ncbi.nlm.nih.gov/16806134
Autor:
Angela D. Wilkins, Anbu Karani Adikesavan, David C. Marciano, Panagiotis Katsonis, Olivier Lichtarge, Rhonald C. Lua
Publikováno v:
Progress in Biophysics and Molecular Biology. 116:194-202
Understanding the molecular basis of protein function remains a central goal of biology, with the hope to elucidate the role of human genes in health and in disease, and to rationally design therapies through targeted molecular perturbations. We revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3605e41124ef8ee19c6265da76ddbd36
https://doi.org/10.1016/j.pbiomolbio.2014.05.004
https://doi.org/10.1016/j.pbiomolbio.2014.05.004
Autor:
Wei Li, Sudipan Karmakar, Anbu Karani Adikesavan, Carolyn L. Smith, Shuang Liu, Liguo Wang, Patricia S. Pardo
Publikováno v:
Molecular and Cellular Biology. 34:1246-1261
The silencing mediator of retinoic acid and thyroid hormone receptors (SMRT) is an established histone deacetylase 3 (HDAC3)-dependent transcriptional corepressor. Microarray analyses of MCF-7 cells transfected with control or SMRT small interfering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e305bec28d1633baba7d1ca42903748f
https://doi.org/10.1128/mcb.01216-13
https://doi.org/10.1128/mcb.01216-13
Publikováno v:
Chemico-Biological Interactions. 294:178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8c75bfe4d7187ebc5f78b4fe213bdf9
https://doi.org/10.1016/j.cbi.2017.05.023
https://doi.org/10.1016/j.cbi.2017.05.023
Publikováno v:
Biochemical and Biophysical Research Communications. 501:826
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc48f95aeace76c2f767e43da136660
https://doi.org/10.1016/j.bbrc.2018.04.169
https://doi.org/10.1016/j.bbrc.2018.04.169
Publikováno v:
Biochemical and Biophysical Research Communications. 377:407-412
Glucose-regulated GRP58 has shown clinical applications to endoplasmic reticulum (ER) stress and cancer. GRP58 is localized in the cytosol, endoplasmic reticulum (ER) and nucleus. Twenty-four amino acids at the N-terminal hydrophobic region are known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be01b2e24f1aca8122a4ae934fde0a54
https://doi.org/10.1016/j.bbrc.2008.09.133
https://doi.org/10.1016/j.bbrc.2008.09.133
Publikováno v:
Molecular Cancer Therapeutics. 6:2719-2727
Glucose regulatory protein (GRP58) is known to mediate mitomycin C (MMC)–induced DNA cross-linking. However, the mechanism remains elusive. We hypothesized that thioredoxin-like domains, one at NH2 terminus and another at COOH terminus, are require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e383b34583ea3c790dc6ecd222feb204
https://doi.org/10.1158/1535-7163.mct-07-0160
https://doi.org/10.1158/1535-7163.mct-07-0160
Autor:
Lawrence A. Donehower, Curtis R. Pickering, Anbu Karani Adikesavan, Ilya B. Novikov, Linda Kato, Christie M. Buchovecky, Meenakshi Nagarajan, Angela D. Wilkins, Shenghua Bao, Andreas Martin Lisewski, Benjamin J. Bachman, Ying Chen, Sam Regenbogen, Olivier Lichtarge, Sumit Bhatia, María E. Terrón-Díaz, Jacques Joseph Labrie, Griff Weber, Ana Lelescu, Peter J. Haas, Stephen K. Boyer, Scott Spangler, Houyin Zhang
Publikováno v:
KDD
We present KnIT, the Knowledge Integration Toolkit, a system for accelerating scientific discovery and predicting previously unknown protein-protein interactions. Such predictions enrich biological research and are pertinent to drug discovery and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e0373c138188c155b045ce7e85d6e7e
https://doi.org/10.1145/2783258.2788609
https://doi.org/10.1145/2783258.2788609
Publikováno v:
Chemico-Biological Interactions. 162:81-87
The anti-cancer drug mitomycin C is metabolically activated to bind and cross-link DNA. The cross-linking contributes significantly to the cytotoxicity. The complex chemical structure of mitomycin C allows its metabolism by several known (cytosolic N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0e0c9a3431bb369726936150cb77a0
https://doi.org/10.1016/j.cbi.2006.05.009
https://doi.org/10.1016/j.cbi.2006.05.009