Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Anbarasu Kumaraswamy"'
Autor:
Anbarasu Kumaraswamy, Zhi Duan, Diana Flores, Chao Zhang, Archana Sehrawat, Ya-Mei Hu, Olivia A. Swaim, Eva Rodansky, William K. Storck, Joshua A. Kuleape, Karan Bedi, Rahul Mannan, Xiao-Ming Wang, Aaron Udager, Visweswaran Ravikumar, Armand Bankhead III, Ilsa Coleman, John K. Lee, Colm Morrissey, Peter S. Nelson, Arul M. Chinnaiyan, Arvind Rao, Zheng Xia, Joel A. Yates, Joshi J. Alumkal
Publikováno v:
JCI Insight, Vol 8, Iss 15 (2023)
Lysine-specific demethylase 1 (LSD1) is a histone demethylase that promotes stemness and cell survival in cancers such as prostate cancer. Most prostate malignancies are adenocarcinomas with luminal differentiation. However, some tumors undergo cellu
Externí odkaz:
https://doaj.org/article/e4a07a2910524a9eab732b3ab8ace38b
Autor:
Daniel J. Coleman, David A. Sampson, Archana Sehrawat, Anbarasu Kumaraswamy, Duanchen Sun, Yuzhuo Wang, Jacob Schwartzman, Joshua Urrutia, Ahn R. Lee, Ilsa M. Coleman, Peter S. Nelson, Xuesen Dong, Colm Morrissey, Eva Corey, Zheng Xia, Joel A. Yates, Joshi J. Alumkal
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 6, Pp 253-262 (2020)
Neuroendocrine prostate cancer (NEPC) is the most virulent form of prostate cancer. Importantly, our recent work examining metastatic biopsy samples demonstrates NEPC is increasing in frequency. In contrast to prostate adenocarcinomas that express a
Externí odkaz:
https://doaj.org/article/d5b944dbbb4c47a8814fa347edf364fc
Autor:
Indu Jose Thoompumkal, Malireddi Rama Krishna Subba Rao, Anbarasu Kumaraswamy, Rehna Krishnan, Sundarasamy Mahalingam
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135845 (2015)
GNL3L is an evolutionarily conserved high molecular weight GTP binding nucleolar protein belonging to HSR1-MMR1 subfamily of GTPases. The present investigation reveals that GNL3L is a nucleo-cytoplasmic shuttling protein and its export from the nucle
Externí odkaz:
https://doaj.org/article/9e63dc3149fb4086ae0e39b92b539d41
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Figure S3 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380d5df6f1565ca06f349c5d1c89338e
https://doi.org/10.1158/1078-0432.22481663.v1
https://doi.org/10.1158/1078-0432.22481663.v1
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Data from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212ea32b543bc433b2e2d94d66815153
https://doi.org/10.1158/1078-0432.22481681
https://doi.org/10.1158/1078-0432.22481681
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Table S2 S4 S6 S7 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16078ca74f4249c0affafe9aadcfadc3
https://doi.org/10.1158/1078-0432.22481645.v1
https://doi.org/10.1158/1078-0432.22481645.v1
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Table S3 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fac14709a2fec2f4b783b7663c42d28
https://doi.org/10.1158/1078-0432.22481642.v1
https://doi.org/10.1158/1078-0432.22481642.v1
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Purpose:Lineage plasticity in prostate cancer—most commonly exemplified by loss of androgen receptor (AR) signaling and a switch from a luminal to alternate differentiation program—is now recognized as a treatment resistance mechanism. Lineage pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048c54987968c92a1c3c681235482238
https://doi.org/10.1158/1078-0432.c.6530747.v1
https://doi.org/10.1158/1078-0432.c.6530747.v1
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Table S8-S12 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3a1a10765a705a50b969da1a429c43
https://doi.org/10.1158/1078-0432.22481636.v1
https://doi.org/10.1158/1078-0432.22481636.v1
Autor:
Anbarasu Kumaraswamy, Joel A. Yates, Felix Y. Feng, Thomas C. Westbrook, Joshi J. Alumkal, Todd M. Morgan, Katherine R. Welker Leng, Christopher P. Evans, Shuang G. Zhao
Publikováno v:
Eur Urol
Context In addition to genetic alterations, epigenetic alterations play a crucial role during prostate cancer progression. A better understanding of the epigenetic factors that promote prostate cancer progression may lead to the design of rational th