Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Anbarasu, Lourdusamy"'
Autor:
Franziska Linke, James E. C. Johnson, Stefanie Kern, Christopher D. Bennett, Anbarasu Lourdusamy, Daniel Lea, Steven C. Clifford, Catherine L. R. Merry, Snow Stolnik, Morgan R. Alexander, Andrew C. Peet, David J. Scurr, Rian L. Griffiths, Anna M. Grabowska, Ian D. Kerr, Beth Coyle
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract The most common malignant brain tumour in children, medulloblastoma (MB), is subdivided into four clinically relevant molecular subgroups, although targeted therapy options informed by understanding of different cellular features are lacking
Externí odkaz:
https://doaj.org/article/8e0594bb9b0f4ee79da8bd0f140e5dd2
Autor:
Huda Alfardus, Maria de los Angeles Estevez-Cebrero, Jonathan Rowlinson, Amna Aboalmaaly, Anbarasu Lourdusamy, Salah Abdelrazig, Catherine Ortori, Richard Grundy, Dong-Hyun Kim, Alan McIntyre, Stuart Smith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract While specific microRNA (miRNA) signatures have been identified in glioblastoma (GBM), the intratumour heterogeneity in miRNA expression has not yet been characterised. In this study, we reveal significant alterations in miRNA expression acr
Externí odkaz:
https://doaj.org/article/70c79d13cb784e25885855238a077df2
Autor:
Alexandra D. Rusu, Zoe E. Cornhill, Brenda Canales Coutiño, Marcos Castellanos Uribe, Anbarasu Lourdusamy, Zsuzsa Markus, Sean T. May, Ruman Rahman, Marios Georgiou
Publikováno v:
Open Biology, Vol 11, Iss 9 (2021)
Approximately 90% of cancer-related deaths can be attributed to a tumour's ability to spread. We have identified CG7379, the fly orthologue of human ING1, as a potent invasion suppressor. ING1 is a type II tumour suppressor with well-established role
Externí odkaz:
https://doaj.org/article/ac1db539b5b844c9955fe2fded805808
Autor:
Brenda Canales Coutiño, Zoe E. Cornhill, Africa Couto, Natalie A. Mack, Alexandra D. Rusu, Usha Nagarajan, Yuen Ngan Fan, Marina R. Hadjicharalambous, Marcos Castellanos Uribe, Amy Burrows, Anbarasu Lourdusamy, Ruman Rahman, Sean T. May, Marios Georgiou
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101237- (2020)
Summary: Metastasis is the leading cause of death for patients with cancer. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumor growth toward malignancy. Advances in genome ch
Externí odkaz:
https://doaj.org/article/63857e0e94984fed9ef235e03070465b
Autor:
Abdolrahman S. Nateri, Axel Behrens, Anbarasu Lourdusamy, Mohammad Ilyas, Bradley Spencer-Dene, Seyed Hossein Kashfi, Anas Saadeddin, Emenike K. Onyido, Roya Babaei-Jadidi, Sheema Almozyan, Belal A. Muhammad
S6. FLYWCH1 mutation in human cancers and analysis of cell cycle by flow cytometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3d07b8d9c77d298d70b0ca562bdbd3
https://doi.org/10.1158/1541-7786.22515355.v1
https://doi.org/10.1158/1541-7786.22515355.v1
Autor:
Abdolrahman S. Nateri, Axel Behrens, Anbarasu Lourdusamy, Mohammad Ilyas, Bradley Spencer-Dene, Seyed Hossein Kashfi, Anas Saadeddin, Emenike K. Onyido, Roya Babaei-Jadidi, Sheema Almozyan, Belal A. Muhammad
This file contains Supplementary Figures 1-9 legends, and Supplementary Tables 1 & 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001daa802bfac3be7cb3f9122b088045
https://doi.org/10.1158/1541-7786.22515343
https://doi.org/10.1158/1541-7786.22515343
Autor:
Abdolrahman S. Nateri, Axel Behrens, Anbarasu Lourdusamy, Mohammad Ilyas, Bradley Spencer-Dene, Seyed Hossein Kashfi, Anas Saadeddin, Emenike K. Onyido, Roya Babaei-Jadidi, Sheema Almozyan, Belal A. Muhammad
Wnt/β-catenin signaling plays a critical role during development of both normal and malignant colorectal cancer tissues. Phosphorylation of β-catenin protein alters its trafficking and function. Such conventional allosteric regulation usually invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c75e90b04da8215776b9e8f9c281735
https://doi.org/10.1158/1541-7786.c.6541051
https://doi.org/10.1158/1541-7786.c.6541051
Autor:
Agathe L. Chédeville, Anbarasu Lourdusamy, Ana Rita Monteiro, Richard Hill, Patricia A. Madureira
Publikováno v:
Biomedicines, Vol 8, Iss 9, p 310 (2020)
Glioblastoma (GB) is the most common and deadly type of primary malignant brain tumor with an average patient survival of only 15–17 months. GBs typically have hypoxic regions associated with aggressiveness and chemoresistance. Using patient derive
Externí odkaz:
https://doaj.org/article/557a3485eaf04f93a8f40719c172c5d3
Autor:
Anbarasu Lourdusamy, Ian D. Kerr, Macha Aldighieri, Franziska Linke, Beth Coyle, Catherine L.R. Merry, Anna M. Grabowska, Snow Stolnik
Publikováno v:
The Journal of Pathology
© 2020 The Authors. The Journal of Pathology published by John Wiley & Sons, Ltd. on behalf of The Pathological Society of Great Britain and Ireland. Medulloblastoma (MB) is the most common malignant brain tumour in children and is subdivided into f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c638dfd313858ca40975892a6895c9
https://doi.org/10.1002/path.5591
https://doi.org/10.1002/path.5591
Autor:
Michael Hüll, Alfredo Ramirez, Oliver Peters, Johannes Kornhuber, Christian P. Müller, Frank Jessen, Arnd Dörfler, Lutz Frölich, Tanja Richter-Schmidinger, Georgios Kogias, Anbarasu Lourdusamy, Jens Wiltfang, Bernd Lenz, Cosima Rhein, Wolfgang Maier, Fernando Boix, Christiane Mühle, Stefan J. Teipel
Publikováno v:
Brain research bulletin 161, 13-20 (2020). doi:10.1016/j.brainresbull.2020.05.001
Calcium/Calmodulin-dependent kinase alpha (αCaMKII) has been shown to play an essential role in synaptic plasticity and in learning and memory in animal models. However, there is little evidence for an involvement in specific memories in humans. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8a76cfafbc6b5115e352f9b8496771
https://doi.org/10.1016/j.brainresbull.2020.05.001
https://doi.org/10.1016/j.brainresbull.2020.05.001