Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anbarasi Kothandapani"'
Autor:
Anbarasi Kothandapani, Samantha R Lewis, Jessica L Noel, Abbey Zacharski, Kyle Krellwitz, Anna Baines, Stephanie Winske, Chad M Vezina, Elena M Kaftanovskaya, Alexander I Agoulnik, Emily M Merton, Martin J Cohn, Joan S Jorgensen
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008810 (2020)
Urogenital tract abnormalities are among the most common congenital defects in humans. Male urogenital development requires Hedgehog-GLI signaling and testicular hormones, but how these pathways interact is unclear. We found that Gli3XtJ mutant mice
Externí odkaz:
https://doaj.org/article/c4d27519870641df92699837de73e702
Autor:
Kandace J. Williams, Vishal P. Sharma, Saravanan Kaliyaperumal, Steve M. Patrick, Anbarasi Kothandapani, Allen G. Schroering
Supplementary Figure 1 from Prolonged Cell Cycle Response of HeLa Cells to Low-Level Alkylation Exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134d0686ae15f8205a3f0bb5a4267e48
https://doi.org/10.1158/0008-5472.22379001.v1
https://doi.org/10.1158/0008-5472.22379001.v1
Autor:
Kandace J. Williams, Vishal P. Sharma, Saravanan Kaliyaperumal, Steve M. Patrick, Anbarasi Kothandapani, Allen G. Schroering
Alkylation chemotherapy has been a long-standing treatment protocol for human neoplasia. N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) is a direct-acting monofunctional alkylator. Temozolomide is a clinical chemotherapeutic equivalent requiring metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d70b504aa94366b52310e86bef3dd0
https://doi.org/10.1158/0008-5472.c.6499083.v1
https://doi.org/10.1158/0008-5472.c.6499083.v1
Publikováno v:
Endocrinology
Two specialized functions of cholesterol during fetal development include serving as a precursor to androgen synthesis and supporting hedgehog (HH) signaling activity. Androgens are produced by the testes to facilitate masculinization of the fetus. R
GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation
Autor:
Samantha R. Lewis, Elena M. Kaftanovskaya, Stephanie Winske, Chad M. Vezina, Martin J. Cohn, Anbarasi Kothandapani, Anna Baines, Jessica Noel, Abbey Zacharski, Emily M. Merton, Alexander I. Agoulnik, Joan S. Jorgensen, Kyle Krellwitz
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008810 (2020)
PLoS Genetics
PLoS Genetics
Urogenital tract abnormalities are among the most common congenital defects in humans. Male urogenital development requires Hedgehog-GLI signaling and testicular hormones, but how these pathways interact is unclear. We found that Gli3XtJ mutant mice
Autor:
Joan S. Jorgensen, Megan L. Koth, Christopher R. Futtner, Anbarasi Kothandapani, Humphrey H.-C. Yao, Annie Novak, S. Alexandra Garcia-Moreno, Barbara Nicol, Kirsten A. Holthusen, Keer Jiang, Makoto Mark Taketo, Danielle M. Maatouk
Publikováno v:
Development.
Members of the Iroquois B (IrxB) homeodomain cluster genes, specifically Irx3 and Irx5, are critical for heart, limb, and bone development. Recently, we reported their importance for oocyte and follicle survival within the developing ovary. Irx3 and
Autor:
Michele Campaigne Larsen, Anbarasi Kothandapani, Colin R. Jefcoate, Joan S. Jorgensen, Jinwoo Lee
Publikováno v:
Molecular and Cellular Endocrinology. 531:111265
STARD1 stimulates cholesterol transfer to mitochondrial CYP11A1 for conversion to pregnenolone. A cholesterol-binding START domain is guided by an N-terminal domain in a cell selective manner. Fetal and adult Leydig cells (FLC, ALC) show distinct Sta
Publikováno v:
In Environmental Toxicology and Pharmacology 2005 20(2):345-350
Autor:
Anbarasi Kothandapani, Xiaojing Su, Tammi L. van Neel, Susan E. Crawford, Tom Walsh, John K. Amory, Max Greenberg, Ivor Clinton, Ashleigh B. Theberge, John H. Day, Joan S. Jorgensen, Colin R. Jefcoate, Tristan M. Nicholson, Charles H. Muller, Omar E. Franco, Jinwoo Lee
Publikováno v:
Lab Chip
Open microfluidic cell culture systems are powerful tools for interrogating biological mechanisms. We have previously presented a microscale cell culture system, based on spontaneous capillary flow of biocompatible hydrogels, that is integrated into
Autor:
Megan L, Koth, S Alexandra, Garcia-Moreno, Annie, Novak, Kirsten A, Holthusen, Anbarasi, Kothandapani, Keer, Jiang, Makoto Mark, Taketo, Barbara, Nicol, Humphrey H-C, Yao, Christopher R, Futtner, Danielle M, Maatouk, Joan S, Jorgensen
Publikováno v:
Development
Members of the Iroquois B (IrxB) homeodomain cluster genes, specifically Irx3 and Irx5, are crucial for heart, limb and bone development. Recently, we reported their importance for oocyte and follicle survival within the developing ovary. Irx3 and Ir