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pro vyhledávání: '"Anatoly D Altstein"'
Autor:
Anatoly D Altstein
Publikováno v:
Transcriptomics: Open Access.
The most accepted concept of the origin of nucleic acids and life is the RNA world hypothesis that is supported by many scientists. There are very strong objections against this hypothesis (problems of selection of compounds in prebiotic conditions,
Autor:
Anatoly D. Altstein, J. R. Stephenson, G. V. Pashvykina, N.V Ovsyannikova, M.F Vorovitch, Ludmila Zakharova, AV Timofeev, Alexander M. Shneider, Mikhail V. Khoretonenko
Publikováno v:
Immunology Letters. 90:161-163
A vaccinia virus recombinant containing the non-structural tick-borne encephalitis virus (TBEV) NS1 gene was developed. The recombinant expressed native dimeric form of the NS1 protein in infected cells and protected mice against lethal infection wit
Autor:
Alexander M. Shneider, Alexei G. Prilipov, Petr O. Ilyinskii, Maria Nurminskaya, Anatoly D. Altstein, Galini Thoidis, Vladimir L. Gabai, Lyudmila G. Zakharova, Evgeny V. Usachev
Publikováno v:
Omics : a journal of integrative biology. 13(3)
Inadvertent cytotoxicity may hinder the expression of many recombinant proteins that are of industrial or medicinal importance. Here, we show that covalent binding of the influenza A cytotoxic protein M2 to a polyglutamine domain (polyQ-M2; QM2) resu
Autor:
Irina I. Akopova, Oleg P. Zhirnov, Elena I. Isaeva, Petr O. Ilyinskii, Anatoly D. Altstein, Lyudmila M. Piskareva, T. E. Konakova, Alexander M. Shneider, Galini Thoidis, Alex Kartashov
Publikováno v:
Influenza and Other Respiratory Viruses
Background Experimental data accumulated over more than a decade indicate that cross-strain protection against influenza may be achieved by immunization with conserved influenza proteins. At the same time, the efficacy of immunization schemes designe
Autor:
L. M. Piskareva, Maxim M. Shmarov, A. K. Gitelman, Petr O. Ilyinskii, Anatoly D. Altstein, Alexander M. Shneider, N. P. Varich, Oleg P. Zhirnov, Ludmila Zakharova, G. V. Pashvykina, Yu. A. Smirnov
Publikováno v:
Archives of virology. 151(5)
Two-fold immunization of Balb/c mice with a vaccinia virus recombinant expressing the NP protein of influenza A/PR8/34 (H1N1) virus under the control of a strong synthetic promoter induced specific antibodies and protected animals against low-dose ch
Publikováno v:
Virus research. 31(1)
A double recombinant of vaccinia virus (W-lacZ/J-tk/F) was obtained, which contains two inverted copies of the virus tk gene, separated by 45 kb: (i) the native copy located in the Hin dIII ragment of the virus genome was inactivated due to insertion
Autor:
Anatoly D. Altstein, Irina M. Grigorieva, Galina V. Pashvykina, Vitaly G. Grigoriev, Vadim Y. Shevlyagin, Ludmila Zakharova
Publikováno v:
Immunology letters. 36(3)
The ability of different recombinant vaccinia viruses (RVV) expressing hepatitis B virus surface antigen (HBsAg) to induce anti-HBs and anti-vaccinia virus responses has been analyzed in mice. The RVVs tested differed with regard to the original vacc
Publikováno v:
Immunology letters. 36(3)
Using five ELISA variants we have analyzed the ratios of the antigenic determinants ‘a’ (a-D), preS2 (preS2-D) and the polymerized human serum albumin binding domains (PHSA-BD) in the hepatitis B virus surface antigen (HBsAg) particles contained
Publikováno v:
The Journal of general virology. 74
Double vaccinia virus recombinants expressing both the T7 RNA polymerase gene, controlled by a weak early poxvirus PF promoter, and the Escherichia coli beta-galactosidase gene, controlled by the phage T7 promoter, have been obtained. The viability o
Autor:
J. R. Stephenson, Ludmila Zakharova, Anatoly D. Altstein, Mikhail V. Khoretonenko, G. V. Pashvykina, AV Timofeev, S. E. Aleshin, Alexander M. Shneider
Publikováno v:
BMC Microbiology
BMC Microbiology, Vol 5, Iss 1, p 45 (2005)
BMC Microbiology, Vol 5, Iss 1, p 45 (2005)
BackgroundHeterologous prime-boost immunization protocols using different gene expression systems have proven to be successful tools in protecting against various diseases in experimental animal models. The main reason for using this approach is to e