Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anatoly Bukovsky"'
Autor:
Harry L. Malech, Thomas Foster City Dull, Sebastian Brenner, C. I. Civin, Joachim Roesler, Michael C. Kelly, Narda L. Whiting-Theobald, Anatoly Bukovsky
Publikováno v:
Blood. 100:4381-4390
HIV-1-derived lentivectors are promising for gene transfer into hematopoietic stem cells but require preclinical in vivo evaluation relevant to specific human diseases. Nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice accept human he
Publikováno v:
Journal of Virology. 73:9992-9999
Vpr is a small accessory protein of human and simian immunodeficiency viruses (HIV and SIV) that is specifically incorporated into virions. Members of the HIV-2/SIV sm /SIV mac lineage of primate lentiviruses also incorporate a related protein design
Publikováno v:
Scopus-Elsevier
Nef is a regulatory gene product of human immunodeficiency virus type 1 (HIV-1) and other primate lentiviruses which enhances virion infectivity by an unknown mechanism. We report here that Nef is detectable at moderate levels in preparations of HIV-
Publikováno v:
Journal of Virology. 70:6820-6825
The Gag-Pol polyprotein of human immunodeficiency virus type 1 is not required for efficient viral particle assembly or release. However, in this report we demonstrate that the synthesis of a truncated Gag-Pol precursor due to a premature termination
Publikováno v:
Virology. 218:269-274
We have examined the role of the membrane-anchoring domain of the HIV-1 glycoproteins in viral glycoprotein function, glycoprotein incorporation, and viral infectivity. For this purpose, we initially exchanged the entire membrane-spanning region with
Publikováno v:
CIÊNCIAVITAE
Scopus-Elsevier
Scopus-Elsevier
The matrix (MA) protein of human immunodeficiency virus type 1 (HIV-1) forms the outer protein shell directly underneath the lipid envelope of the virion. The MA protein has a key role in different aspects of virus assembly, including the incorporati
Publikováno v:
Journal of Virology. 68:8180-8187
A series of deletions was introduced into the CA domain of the human immunodeficiency virus type 1 Gag polyprotein to examine its role in virus particle and core formation. The mutations resulted in two phenotypes, indicating the existence of two fun
Autor:
Luigi Naldini, Jin-Ping Song, Robert Radeke, Ryan Mcguinness, Deborah Farson, Rochelle Witt, Tom Dull, Anatoly Bukovsky, Michael C. Kelly, Antonella Consiglio
Publikováno v:
HUMAN GENE THERAPY
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
HUM GENE THER
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
HUM GENE THER
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
We have successfully generated and characterized a stable packaging cell line for HIV-1-based vectors. To allow safe production of vector, a minimal packaging construct carrying only the coding sequences of the HIV-1 gag-pol, tat, and rev genes was s
Interaction of human immunodeficiency virus-derived vectors with wild-type virus in transduced cells
Publikováno v:
Journal of virology. 73(8)
The interaction of human immunodeficiency virus (HIV)-derived vectors with wild-type virus was analyzed in transduced cells. Vector transcripts upregulated by infection had no measurable effect on HIV type 1 (HIV-1) expression but competed efficientl
Autor:
Dulce Quiroz, Ronald J. Mandel, Romain Zufferey, Thomas Foster City Dull, Didier Trono, Luigi Naldini, Anatoly Bukovsky
Publikováno v:
Scopus-Elsevier
In vivo transduction of nondividing cells by human immunodeficiency virus type 1 (HIV-1)-based vectors results in transgene expression that is stable over several months. However, the use of HIV-1 vectors raises concerns about their safety. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ccf1605e8010a9dcb9431e42eaae27
https://europepmc.org/articles/PMC110499/
https://europepmc.org/articles/PMC110499/