Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Anatoly B. Kolomeisky"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Base editors can edit target nucleotides, and identical ones that are within the editing window. Here the authors build an analytical model to propose general principles of editor design to reduce bystander effects.
Externí odkaz:
https://doaj.org/article/cad9f9a2161f45c0a9f734f112a85fde
Autor:
Mohammad S. Safari, Zhiqing Wang, Kunaal Tailor, Anatoly B. Kolomeisky, Jacinta C. Conrad, Peter G. Vekilov
Publikováno v:
iScience, Vol 12, Iss , Pp 342-355 (2019)
Summary: About half of human cancers are associated with mutations of the tumor suppressor p53. Gained oncogenic functions of the mutants have been related to aggregation behaviors of wild-type and mutant p53. The thermodynamic and kinetic mechanisms
Externí odkaz:
https://doaj.org/article/2115390650724f12a24b2194be1d87df
Publikováno v:
The Journal of Physical Chemistry Letters. 14:4096-4103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00670f0e951ece2f03f8520a66037df
https://doi.org/10.1021/acs.jpclett.3c00529
https://doi.org/10.1021/acs.jpclett.3c00529
Publikováno v:
The Journal of Physical Chemistry Letters. 14:3422-3429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cedacabcf92100289a1f78ab79faf8d
https://doi.org/10.1021/acs.jpclett.3c00345
https://doi.org/10.1021/acs.jpclett.3c00345
Publikováno v:
The Journal of Physical Chemistry B. 126:10813-10821
The organization of the nucleosome array is a critical component of the chromatin assembly into higher order structure as well as its function. Here, we investigated the contributions of the DNA sequence and internucleosomal interactions on the organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d771972ef6f6d3e9879dc1488b7c7483
https://doi.org/10.1021/acs.jpcb.2c05321
https://doi.org/10.1021/acs.jpcb.2c05321
Publikováno v:
The Journal of Physical Chemistry B. 126:7365-7372
Antimicrobial peptides (AMPs), or defence peptides, are compounds naturally produced during immune responses of living organisms against bacterial infections that are currently actively considered as promising alternatives to antibiotics. Recent expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf633455ca35629ac8d71ccc1785abf
https://doi.org/10.1021/acs.jpcb.2c05345
https://doi.org/10.1021/acs.jpcb.2c05345
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9800
The synaptic protein–DNA complexes, formed by specialized proteins that bridge two or more distant sites on DNA, are critically involved in various genetic processes. However, the molecular mechanism by which the protein searches for these sites an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::3c635fd372fbd346b0cd8212acddcba2
Autor:
Alex Berlaga, Anatoly B. Kolomeisky
Publikováno v:
The Journal of Physical Chemistry Letters. 13:5405-5412
Biological cells frequently exhibit a so-called secondary active transport by moving various species across their membranes. In this mode of transport, an energetically favorable transmembrane gradient of one type of molecule is used to drive another
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801883921a786298198a8ea26c421d28
https://doi.org/10.1021/acs.jpclett.2c01232
https://doi.org/10.1021/acs.jpclett.2c01232
The synaptic protein-DNA complexes, formed by specialized proteins that bridge two or more distant sites on DNA, are critically involved in various genetic processes. However, the molecular mechanism by which the protein searches for these sites and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fea553d388d43dea10df989b7277d7a
https://doi.org/10.1101/2023.04.27.538641
https://doi.org/10.1101/2023.04.27.538641
Publikováno v:
The Journal of Physical Chemistry B. 126:4061-4068
All major biological processes start after protein molecules known as transcription factors detect specific regulatory sequences on DNA and initiate genetic expression by associating to them. But in eukaryotic cells, much of the DNA is covered by nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52da3a1ac983e020a59c8bcc9abd2de8
https://doi.org/10.1021/acs.jpcb.2c01931
https://doi.org/10.1021/acs.jpcb.2c01931