Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Anatoly B. Kolomeisky"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Base editors can edit target nucleotides, and identical ones that are within the editing window. Here the authors build an analytical model to propose general principles of editor design to reduce bystander effects.
Externí odkaz:
https://doaj.org/article/cad9f9a2161f45c0a9f734f112a85fde
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9800 (2023)
The synaptic protein–DNA complexes, formed by specialized proteins that bridge two or more distant sites on DNA, are critically involved in various genetic processes. However, the molecular mechanism by which the protein searches for these sites an
Externí odkaz:
https://doaj.org/article/62a0bc7f84b143ce897c63e1a3e3e20e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12916 (2022)
The interplay between the mechanical properties of double-stranded and single-stranded DNA is a phenomenon that contributes to various genetic processes in which both types of DNA structures coexist. Highly stiff DNA duplexes can stretch single-stran
Externí odkaz:
https://doaj.org/article/155c7c912eb64f658614625870056fd9
Autor:
Mohammad S. Safari, Zhiqing Wang, Kunaal Tailor, Anatoly B. Kolomeisky, Jacinta C. Conrad, Peter G. Vekilov
Publikováno v:
iScience, Vol 12, Iss , Pp 342-355 (2019)
Summary: About half of human cancers are associated with mutations of the tumor suppressor p53. Gained oncogenic functions of the mutants have been related to aggregation behaviors of wild-type and mutant p53. The thermodynamic and kinetic mechanisms
Externí odkaz:
https://doaj.org/article/2115390650724f12a24b2194be1d87df
Publikováno v:
The Journal of Physical Chemistry Letters. 14:4096-4103
Publikováno v:
The Journal of Physical Chemistry Letters. 14:3422-3429
Publikováno v:
The Journal of Physical Chemistry B. 126:10813-10821
The organization of the nucleosome array is a critical component of the chromatin assembly into higher order structure as well as its function. Here, we investigated the contributions of the DNA sequence and internucleosomal interactions on the organ
Publikováno v:
The Journal of Physical Chemistry B. 126:7365-7372
Antimicrobial peptides (AMPs), or defence peptides, are compounds naturally produced during immune responses of living organisms against bacterial infections that are currently actively considered as promising alternatives to antibiotics. Recent expe
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9800
The synaptic protein–DNA complexes, formed by specialized proteins that bridge two or more distant sites on DNA, are critically involved in various genetic processes. However, the molecular mechanism by which the protein searches for these sites an
Autor:
Alex Berlaga, Anatoly B. Kolomeisky
Publikováno v:
The Journal of Physical Chemistry Letters. 13:5405-5412
Biological cells frequently exhibit a so-called secondary active transport by moving various species across their membranes. In this mode of transport, an energetically favorable transmembrane gradient of one type of molecule is used to drive another