Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Anatoli S. Gleiberman"'
Autor:
Natalia Fedtsova, Elena A. Komarova, Kellee F. Greene, Liliya R. Novototskaya, Ivan Molodtsov, Craig M. Brackett, Evguenia Strom, Anatoli S. Gleiberman, Alexander N. Shakhov, Andrei V. Gudkov
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Abstract Transplantation of bone marrow (BM) is made possible by the differential sensitivity of its stromal and hematopoietic components to preconditioning by radiation and/or chemotherapeutic drugs. These genotoxic treatments eliminate host hematop
Externí odkaz:
https://doaj.org/article/567e32f8c63e48f8b13d02edbbb27399
Autor:
Vadim Mett, Oleg V. Kurnasov, Ivan A. Bespalov, Ivan Molodtsov, Craig M. Brackett, Lyudmila G. Burdelya, Andrei A. Purmal, Anatoli S. Gleiberman, Ilia A. Toshkov, Catherine A. Burkhart, Yakov N. Kogan, Ekaterina L. Andrianova, Andrei V. Gudkov, Andrei L. Osterman
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Mett et al. describe development of GP532, a substantially deimmunized derivative of Toll-like receptor 5 (TLR5) agonist entolimod. GP532 has mutations eliminating key B- and T-cell epitopes and an inflammasome-activating domain yet remains a potent
Externí odkaz:
https://doaj.org/article/bcafc6dab7b74c02bc2aec45e9ac993a
Autor:
Alexandra V. Vylegzhanina, Ivan A. Bespalov, Ksenia A. Novototskaya-Vlasova, Brandon M. Hall, Anatoli S. Gleiberman, Han Yu, Olga V. Leontieva, Katerina I. Leonova, Oleg V. Kurnasov, Andrei L. Osterman, Grace K. Dy, Alexey A. Komissarov, Elena Vasilieva, Jeff Gehlhausen, Akiko Iwasaki, Christine B. Ambrosone, Takemasa Tsuji, Junko Matsuzaki, Kunle Odunsi, Ekaterina L. Andrianova, Andrei V. Gudkov
LINE-1 (L1), the most abundant family of autonomous retrotransposons occupying over 17% of human DNA, is epigenetically silenced in normal tissues but frequently derepressed in cancer, suggesting that L1-encoded proteins may act as tumor-associated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8477abcfdeea873bdfbc1aaddff4cbf4
https://doi.org/10.1101/2023.02.03.526997
https://doi.org/10.1101/2023.02.03.526997
Autor:
Ksenia A. Novototskaya-Vlasova, Nickolay S. Neznanov, Ivan Molodtsov, Brandon M. Hall, Mairead Commane, Anatoli S. Gleiberman, Jayne Murray, Michelle Haber, Murray D. Norris, Katerina I. Leonova, Andrei V. Gudkov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(49)
Activation of endogenous retrotransposons frequently occurs in cancer cells and contributes to tumor genomic instability. To test whether inhibition of retrotranspositions has an anticancer effect, we used treatment with the nucleoside reverse transc
Autor:
Craig M. Brackett, Catherine Burkhart, Ilia Toshkov, Andrei L. Osterman, Ivan A. Bespalov, Andrei Purmal, Vadim L. Mett, Andrei V. Gudkov, Lyudmila G. Burdelya, Yakov N. Kogan, Anatoli S. Gleiberman, Ekaterina L. Andrianova, Ivan Molodtsov, Oleg V. Kurnasov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
The Toll-like receptor 5 (TLR5) agonist entolimod, a derivative of Salmonella flagellin, has therapeutic potential for several indications including radioprotection and cancer immunotherapy. However, in Phase 1 human studies, entolimod induced a rapi
Autor:
Karen K. Kuropatwinski, Olga V. Chernova, Bryan Gillard, Anatoli S. Gleiberman, Michael T. Moser, Michelle Wrobel, Ilia Toshkov, Ellen Karasik, Andrei V. Gudkov, Ekaterina L. Andrianova, Barbara A. Foster, Marina P. Antoch
Publikováno v:
Oncotarget
// Marina P. Antoch 1 , Michelle Wrobel 2 , Bryan Gillard 1 , Karen K. Kuropatwinski 1 , Ilia Toshkov 2 , Anatoli S. Gleiberman 2 , Ellen Karasik 1 , Michael T. Moser 1 , Barbara A. Foster 1 , Ekaterina L. Andrianova 2 , Olga V. Chernova 2 and Andrei
Autor:
Kellee F. Greene, Anatoli S. Gleiberman, Alexander N. Shakhov, Elena A. Komarova, Natalia Fedtsova, Evguenia Strom, Craig M. Brackett, Andrei V. Gudkov, Ivan Molodtsov, Liliya R. Novototskaya
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Transplantation of bone marrow (BM) is made possible by the differential sensitivity of its stromal and hematopoietic components to preconditioning by radiation and/or chemotherapeutic drugs. These genotoxic treatments eliminate host hematopoietic pr
Autor:
David Frescas, Evguenia Strom, Tamara Tchkonia, Valeria Kogan, Brandon M. Hall, Slavoljub Vujcic, Yi Zhu, Peter Krasnov, James L. Kirkland, Olga B. Chernova, Igor Koman, Marina P. Antoch, Andrei V. Gudkov, Olga V. Leontieva, Anatoli S. Gleiberman
Publikováno v:
Aging Cell
Adipose tissue is recognized as a major source of systemic inflammation with age, driving age‐related tissue dysfunction and pathogenesis. Macrophages (Mφ) are central to these changes yet adipose tissue Mφ (ATMs) from aged mice remain poorly cha
Autor:
Elena Rydkina, Peter Krasnov, Karina Balan, Vitaly Balan, Evguenia Strom, Brandon M. Hall, Anatoli S. Gleiberman, Camila Rosat Consiglio, Sandra O. Gollnick, Andrei V. Gudkov, Ilya Gitlin, Slavoljub Vujcic, Lauren P. Virtuoso, Katerina I. Leonova, Olga B. Chernova
Publikováno v:
Aging (Albany NY)
Constitutive p16Ink4a expression, along with senescence-associated β-galactosidase (SAβG), are commonly accepted biomarkers of senescent cells (SCs). Recent reports attributed improvement of the healthspan of aged mice following p16Ink4a-positive c
Autor:
David Frescas, Brandon M. Hall, Slavoljub Vujcic, Lauren P. Virtuoso, Mahima Gupta, Evguenia Strom, Olga B. Chernova, Elena Rydkina, Anatoli S. Gleiberman, Vitaly Balan, Andrei V. Gudkov
Publikováno v:
Cell Cycle. 16:1526-1533
Age-related health decline has been attributed to the accumulation of senescent cells recognized in vivo by p16(Ink4a) expression. The pharmacological elimination of p16(Ink4a)-positive cells from the tissues of mice was shown to extend a healthy lif