Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Anatoli S Gleiberman"'
Autor:
Gary J Haderski, Bojidar M Kandar, Craig M Brackett, Ilia M Toshkov, Christopher P Johnson, Geraldine M Paszkiewicz, Venkatesh Natarajan, Anatoli S Gleiberman, Andrei V Gudkov, Lyudmila G Burdelya
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0227940 (2020)
Tumor necrosis factor alpha (TNF) is capable of inducing regression of solid tumors. However, TNF released in response to Toll-like receptor 4 (TLR4) activation by bacterial lipopolysaccharide (LPS) is the key mediator of cytokine storm and septic sh
Externí odkaz:
https://doaj.org/article/aff8832bcd384418b01c7670ffe0eb0c
Autor:
Vadim I Krivokrysenko, Ilia A Toshkov, Anatoli S Gleiberman, Peter Krasnov, Inna Shyshynova, Ivan Bespalov, Ratan K Maitra, Natalya V Narizhneva, Vijay K Singh, Mark H Whitnall, Andrei A Purmal, Alexander N Shakhov, Andrei V Gudkov, Elena Feinstein
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0135388 (2015)
There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in nuclear emergencies. An ideal MRC would be effective even when administered well after radiation
Externí odkaz:
https://doaj.org/article/6865a28f972e46fe8ca473ec1865cf65
Autor:
Alexandra V. Vylegzhanina, Ivan A. Bespalov, Ksenia A. Novototskaya-Vlasova, Brandon M. Hall, Anatoli S. Gleiberman, Han Yu, Olga V. Leontieva, Katerina I. Leonova, Oleg V. Kurnasov, Andrei L. Osterman, Grace K. Dy, Alexey A. Komissarov, Elena Vasilieva, Jeff Gehlhausen, Akiko Iwasaki, Christine B. Ambrosone, Takemasa Tsuji, Junko Matsuzaki, Kunle Odunsi, Ekaterina L. Andrianova, Andrei V. Gudkov
LINE-1 (L1), the most abundant family of autonomous retrotransposons occupying over 17% of human DNA, is epigenetically silenced in normal tissues but frequently derepressed in cancer, suggesting that L1-encoded proteins may act as tumor-associated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8477abcfdeea873bdfbc1aaddff4cbf4
https://doi.org/10.1101/2023.02.03.526997
https://doi.org/10.1101/2023.02.03.526997
Autor:
Ksenia A. Novototskaya-Vlasova, Nickolay S. Neznanov, Ivan Molodtsov, Brandon M. Hall, Mairead Commane, Anatoli S. Gleiberman, Jayne Murray, Michelle Haber, Murray D. Norris, Katerina I. Leonova, Andrei V. Gudkov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(49)
Activation of endogenous retrotransposons frequently occurs in cancer cells and contributes to tumor genomic instability. To test whether inhibition of retrotranspositions has an anticancer effect, we used treatment with the nucleoside reverse transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ce780db800bf7e57eabc5db16e5501
https://pubmed.ncbi.nlm.nih.gov/36449545
https://pubmed.ncbi.nlm.nih.gov/36449545
Autor:
Craig M. Brackett, Catherine Burkhart, Ilia Toshkov, Andrei L. Osterman, Ivan A. Bespalov, Andrei Purmal, Vadim L. Mett, Andrei V. Gudkov, Lyudmila G. Burdelya, Yakov N. Kogan, Anatoli S. Gleiberman, Ekaterina L. Andrianova, Ivan Molodtsov, Oleg V. Kurnasov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
The Toll-like receptor 5 (TLR5) agonist entolimod, a derivative of Salmonella flagellin, has therapeutic potential for several indications including radioprotection and cancer immunotherapy. However, in Phase 1 human studies, entolimod induced a rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdef2dd5c9aac4df928eea9fe09e4c96
https://doaj.org/article/bcafc6dab7b74c02bc2aec45e9ac993a
https://doaj.org/article/bcafc6dab7b74c02bc2aec45e9ac993a
Autor:
Karen K. Kuropatwinski, Olga V. Chernova, Bryan Gillard, Anatoli S. Gleiberman, Michael T. Moser, Michelle Wrobel, Ilia Toshkov, Ellen Karasik, Andrei V. Gudkov, Ekaterina L. Andrianova, Barbara A. Foster, Marina P. Antoch
Publikováno v:
Oncotarget
// Marina P. Antoch 1 , Michelle Wrobel 2 , Bryan Gillard 1 , Karen K. Kuropatwinski 1 , Ilia Toshkov 2 , Anatoli S. Gleiberman 2 , Ellen Karasik 1 , Michael T. Moser 1 , Barbara A. Foster 1 , Ekaterina L. Andrianova 2 , Olga V. Chernova 2 and Andrei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b172ce04a3f86af6a0bf8cffd338b8b1
http://europepmc.org/articles/PMC7170500
http://europepmc.org/articles/PMC7170500
Autor:
Kellee F. Greene, Anatoli S. Gleiberman, Alexander N. Shakhov, Elena A. Komarova, Natalia Fedtsova, Evguenia Strom, Craig M. Brackett, Andrei V. Gudkov, Ivan Molodtsov, Liliya R. Novototskaya
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Transplantation of bone marrow (BM) is made possible by the differential sensitivity of its stromal and hematopoietic components to preconditioning by radiation and/or chemotherapeutic drugs. These genotoxic treatments eliminate host hematopoietic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73009fdcba6cd3a55b4d5176715b514e
http://europepmc.org/articles/PMC8154997
http://europepmc.org/articles/PMC8154997
Autor:
David Frescas, Evguenia Strom, Tamara Tchkonia, Valeria Kogan, Brandon M. Hall, Slavoljub Vujcic, Yi Zhu, Peter Krasnov, James L. Kirkland, Olga B. Chernova, Igor Koman, Marina P. Antoch, Andrei V. Gudkov, Olga V. Leontieva, Anatoli S. Gleiberman
Publikováno v:
Aging Cell
Adipose tissue is recognized as a major source of systemic inflammation with age, driving age‐related tissue dysfunction and pathogenesis. Macrophages (Mφ) are central to these changes yet adipose tissue Mφ (ATMs) from aged mice remain poorly cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23db66c340cf3e954a94d54922273730
http://europepmc.org/articles/PMC7576241
http://europepmc.org/articles/PMC7576241
Autor:
Elena Rydkina, Peter Krasnov, Karina Balan, Vitaly Balan, Evguenia Strom, Brandon M. Hall, Anatoli S. Gleiberman, Camila Rosat Consiglio, Sandra O. Gollnick, Andrei V. Gudkov, Ilya Gitlin, Slavoljub Vujcic, Lauren P. Virtuoso, Katerina I. Leonova, Olga B. Chernova
Publikováno v:
Aging (Albany NY)
Constitutive p16Ink4a expression, along with senescence-associated β-galactosidase (SAβG), are commonly accepted biomarkers of senescent cells (SCs). Recent reports attributed improvement of the healthspan of aged mice following p16Ink4a-positive c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf409a562dc24a7dbe07fa1490b9eab
http://europepmc.org/articles/PMC5611982
http://europepmc.org/articles/PMC5611982
Autor:
David Frescas, Brandon M. Hall, Slavoljub Vujcic, Lauren P. Virtuoso, Mahima Gupta, Evguenia Strom, Olga B. Chernova, Elena Rydkina, Anatoli S. Gleiberman, Vitaly Balan, Andrei V. Gudkov
Publikováno v:
Cell Cycle. 16:1526-1533
Age-related health decline has been attributed to the accumulation of senescent cells recognized in vivo by p16(Ink4a) expression. The pharmacological elimination of p16(Ink4a)-positive cells from the tissues of mice was shown to extend a healthy lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00069bbfd5317561dc69bf20edd2809a
https://doi.org/10.1080/15384101.2017.1339850
https://doi.org/10.1080/15384101.2017.1339850