The Modelling of a Cure Fraction in Bivariate Time-to-Event Data

Autor: Andreas Wienke, Isabella Locatelli, Anatoli I. Yashin

Publikováno v: Austrian Journal of Statistics, Vol 35, Iss 1 (2016)

Three correlated frailty models are used to analyze bivariate timeto- event data by assuming gamma, log-normal and compound Poisson distributed frailty. All approaches allow to deal with right censored lifetime data and account for heterogeneity as w

Externí odkaz: https://doaj.org/article/590db0651de647d4ae2c4a6e1a1eb44e

Sex Differences in Genetic Associations With Longevity

Autor: Liang Sun, Qihua Tan, Zhihua Chen, Jianxin Li, Anatoli I. Yashin, Enjun Xie, Chen Bai, Yuebin Lv, Rui Ye, Eline Slagboom, Joris Deelen, Yong Hou, Lars Bolund, Xiao-Li Tian, Chao Nie, Paola Sebastiani, Kaare Christensen, James W. Vaupel, Junxia Min, Angela M. O'Rand, Jean-Marie Robine, Xiao Liu, Wei Tao, Yi Zeng, Anastasia Gurinovich, William K. Gottschalk, Claudio Franceschi, Huanming Yang, Thomas T. Perls, Xun Xu, Xiaomin Liu, Michael W. Lutz, Jun Gu, Jiehua Lu, Kenneth C. Land, Ze Yang, Jichun Xie, Ting Ni, Huashuai Chen, Elizabeth R. Hauser, Xiaoming Shi, Zhaoxue Yin

Publikováno v: JAMA Network Open
JAMA Network Open, American Medical Association, 2018, 1 (4), pp.e181670. ⟨10.1001/jamanetworkopen.2018.1670⟩
Jama Network Open, 1(4)
Zeng, Y, Nie, C, Min, J, Chen, H, Liu, X, Ye, R, Chen, Z, Bai, C, Xie, E, Yin, Z, Lv, Y, Lu, J, Li, J, Ni, T, Bolund, L, Land, K C, Yashin, A, O'Rand, A M, Sun, L, Yang, Z, Tao, W, Gurinovich, A, Franceschi, C, Xie, J, Gu, J, Hou, Y, Liu, X, Xu, X, Robine, J-M, Deelen, J, Sebastiani, P, Slagboom, E, Perls, T, Hauser, E, Gottschalk, W, Tan, Q, Christensen, K, Shi, X, Lutz, M, Tian, X-L, Yang, H & Vaupel, J 2018, ' Sex Differences in Genetic Associations With Longevity ', JAMA network open, vol. 1, no. 4 . https://doi.org/10.1001/jamanetworkopen.2018.1670
Zeng, Y, Nie, C, Min, J, Chen, H, Liu, X, Ye, R, Chen, Z, Bai, C, Xie, E, Yin, Z, Lv, Y, Lu, J, Li, J, Ni, T, Bolund, L, Land, K C, Yashin, A I, O'Rand, A M, Sun, L, Yang, Z, Tao, W, Gurinovich, A, Franceschi, C, Xie, J, Gu, J, Hou, Y, Liu, X, Xu, X, Robine, J-M, Deelen, J, Sebastiani, P, Slagboom, E, Perls, T T, Hauser, E R, Gottschalk, W, Tan, Q, Christensen, K, Shi, X, Lutz, M, Tian, X-L, Yang, H & Vaupel, J W 2018, ' Sex Differences in Genetic Associations With Longevity ', JAMA Network Open, vol. 1, no. 4, e181670 . https://doi.org/10.1001/jamanetworkopen.2018.1670
JAMA Netw Open

Importance: Sex differences in genetic associations with human longevity remain largely unknown; investigations on this topic are important for individualized health care. Objective: To explore sex differences in genetic associations with longevity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec67d7d9210e9ff30d90f0c19ec3f2db
https://hal-cnrs.archives-ouvertes.fr/hal-03480024

Modeling of Immunosenescence and Risk of Death from Respiratory Infections: Evaluation of the Role of Antigenic Load and Population Heterogeneity

Autor: Elisabetta Barbi, A. A. Romanyukha, Claudio Franceschi, Graziella Caselli, T. E. Sannikova, Anatoli I. Yashin

It is well known that efficacy of immune functions declines with age. It results in an increase of severity and duration of respiratory infections and also in dramatic growth of risk of death due to these diseases after age 65. The goal of this work

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018ce631eb2c7b1a6a65cb3c8b3b8890
http://hdl.handle.net/11573/1011096

Interaction between FOXO1A-209 Genotype and Tea Drinking is Significantly Associated with Reduced Mortality at Advanced Ages

Autor: Ming Q, Xiao-Li Tian, Yi Zeng, Xiaomin Liu, Ting Ni, Michael W. Lutz, Qihua Tan, Lei Feng, Jianxin Li, Li Y, Jiehua Lu, James W. Vaupel, Yang Z, Chao Nie, Willcox Dc, Elizabeth R. Hauser, Bradley J. Willcox, William K. Gottschalk, Lars Bolund, Simon G. Gregory, Huashuai Chen, Wei Tao, Junxia Min, Anatoli I. Yashin, Jun Gu, Rongping Ruan, Kenneth C. Land, Huanming Yang, Zhang F

Publikováno v: Zeng, Y, Chen, H, Ni, T, Ruan, R, Nie, C, Liu, X, Feng, L, Zhang, F, Lu, J, Li, J, Li, Y, Tao, W, Gottschalk, W, Lutz, M, Land, K, Yashin, A I, Tan, Q, Yang, Z, Bolund, L, Qi, M, Yang, H, Min, J, Willcox, C D, Willcox, B, Gu, J, Hauser, E, Tian, X-L & Vaupel, J W 2016, ' Interaction between FOXO1A-209 Genotype and Tea Drinking is Significantly Associated with Reduced Mortality at Advanced Ages ', Rejuvenation Research, vol. 19, no. 3, pp. 195-203 . https://doi.org/10.1089/rej.2015.1737
Zeng, Y, Chen, H, Ni, T, Ruan, R, Nie, C, Liu, X, Feng, L, Zhang, F, Lu, J, Li, J, Li, Y, Tao, W, Gregory, S G, Gottschalk, W, Lutz, M, Land, K, Yashin, A I, Tan, Q, Yang, Z, Bolund, L, Qi, M, Yang, H, Min, J, Willcox, C D, Willcox, B, Gu, J, Hauser, E, Tian, X-L & Vaupel, J W 2016, ' Interaction between the FOXO1A-209 Genotype and Tea Drinking is Significantly Associated with Reduced Mortality at Advanced Ages ', Rejuvenation Research, vol. 19, no. 3, pp. 195-203 . https://doi.org/10.1089/rej.2015.1737

On the basis of the genotypic/phenotypic data from Chinese Longitudinal Healthy Longevity Survey (CLHLS) and Cox proportional hazard model, the present study demonstrates that interactions between carrying FOXO1A-209 genotypes and tea drinking are si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647154e0a632f3c8b69df324c55f2f72
https://pure.au.dk/portal/da/publications/interaction-between-foxo1a209-genotype-and-tea-drinking-is-significantly-associated-with-reduced-mortality-at-advanced-ages(78457f09-f0be-4255-b709-98e9e8f075fd).html

The quadratic hazard model for analyzing longitudinal data on aging, health, and the life span

Autor: Anatoli I. Yashin, Kenneth C. Land, Svetlana V. Ukraintseva, Igor Akushevich, Eric Stallard, Konstantin G. Arbeev, Alexander M. Kulminski

Publikováno v: Physics of Life Reviews. 9:177-188

A better understanding of processes and mechanisms linking human aging with changes in health status and survival requires methods capable of analyzing new data that take into account knowledge about these processes accumulated in the field. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028f2082e59676e5dc0ef1759b276ad2
https://doi.org/10.1016/j.plrev.2012.05.002