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pro vyhledávání: '"Anatha, Sadhana"'
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 11. Target ALS Human Postmortem Brain Tissue Cohort. Target ALS Human Postmortem Brain Tissue Cohort. All diagnoses and identifiers were the same for the three brain regions provided (occipital cortex, cerebellum, and motor cortex).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1059fa1b6d22930a5eed3e8c38dfc34
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 3 Transection efficiency is not altered by DPR expression. U2-OS cells were co-transfected with a GFP expression plasmid (1 μg) and either pcDNA, PR, GR, or GA plasmids (1 μg). Using FACS, we quantified the number of GFP expressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc238d1135d9cf557a9ea5159806449a
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 2 Nucleolar localization of PR is dependent on NPM1 expression. A) Representative images of U-2 OS cells transfected with a plasmid expressing HA-PR (PR) and immunolabeled with anti-PR (red) and anti-nucleophosmin (NPM1) (green) antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2d6f685d73ae25ee6a31d5f665693e
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 7 Quantification of DNA damage markers in patient derived motor neurons. Western blot analysis of total protein lysates from motor neurons derived from two iPSC lines from unaffected controls (CTL-1, CTL-2) and two lines from C9ALS pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23dd5161b4bcb438076d8f66554e0f69
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 4. Validation of NPM1 knockdown and PR overexpression. In parallel with the quantification of SSA and NHEJ (Fig. 3), a subset of cells were transfected with either a control (CTL) siRNA, a NPM1 specific siRNA, an empty control vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f497cdc5e57bd4267042ca15914acdf
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 8. Genome editing eliminates the C9ORF72 hexanucleotide repeat expansion. A) Schematic of editing strategy: adeno-associated viral (AAV) transduction of iPSCs derived from a C9ALS/FTD patient, titration, clonal selection and isolation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a799860bfcd8e142eca775eda416dda9
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Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 6. Validation of DNA damage induction. A) DNA double strand break inducers validated through immunoblotting. B) Super resolution (STORM) microscopy reveals increased γH2AX (red) and phosphorylated RAD52 (green) immunofluorescence and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dff3f324b335187b7b348cc566b7ecc9
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 6. Validation of DNA damage induction. A) DNA double strand break inducers validated through immunoblotting. B) Super resolution (STORM) microscopy reveals increased γH2AX (red) and phosphorylated RAD52 (green) immunofluorescence and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4166c77386ece0096c572406ff90eec3
Autor:
Andrade, Nadja, Ramic, Melina, Esanov, Rustam, Wenjun Liu, Rybin, Mathew, Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler, Chee, Nancy, Anatha, Sadhana, Gendron, Tania, Wahlestedt, Claes, Yanbin Zhang, Benatar, Michael, Mueller, Christian, Zeier, Zane
Additional file 10 Quantification of DNA damage foci in C9ORF72 iPSC neurons. A) Representative images of iPSC neuronal cultures immuno-stained with γH2AX (green), Tuj-1 (red) and DAPI (blue). B-D) Quantification of γH2AX mean fluorescence normaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5072009e54c1c19bed9e23a0a3a96d0d