Zobrazeno 1 - 10 of 188 pro vyhledávání: '"Anat R Tambur"'
1
Akademický článek
Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells.
Autor: Yuming Yu, Jennifer R Zitzner, Josetta Houlihan, Nancy Herrera, Luting Xu, Joshua Miller, James M Mathew, Anat R Tambur, Xunrong Luo
Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28948 (2011)
Human CD8(+) regulatory T cells, particularly the CD8(+)CD28(-) T suppressor cells, have emerged as an important modulator of alloimmunity. Understanding the conditions under which these cells are induced and/or expanded would greatly facilitate thei
Externí odkaz: https://doaj.org/article/77426541cf634fa0b0558414f9dbd48a
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2
Akademický článek
Requirement of cognate CD4+ T-cell recognition for the regulation of allospecific CTL by human CD4+ CD127- CD25+ FOXP3+ cells generated in MLR.
Autor: Yuming Yu, Joshua Miller, Joseph R Leventhal, Anat R Tambur, Dhivya Chandrasekaran, Josh Levitsky, Xunrong Luo, James M Mathew
Publikováno v: PLoS ONE, Vol 6, Iss 7, p e22450 (2011)
Although immunoregulation of alloreactive human CTLs has been described, the direct influence of CD4(+) Tregs on CD8(+) cytotoxicity and the interactive mechanisms have not been well clarified. Therefore, human CD4(+)CD127(-)CD25(+)FOXP3(+) Tregs wer
Externí odkaz: https://doaj.org/article/797954c2cca440269ab1662bea69e524
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3
Akademický článek
HLA molecular mismatches and induced donor-specific tolerance in combined living donor kidney and hematopoietic stem cell transplantation
Autor: Aleksandar Senev, Anat R. Tambur, Vasilis Kosmoliaptsis, Hannah Charlotte Copley, Cynthia García-Sánchez, Crystal Usenko, Suzanne T. Ildstad, Joseph R. Leventhal
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionWe investigated the potential role of HLA molecular mismatches (MM) in achieving stable chimerism, allowing for donor-specific tolerance in patients undergoing combined living donor kidney and hematopoietic stem cell transplantation (HSCT
Externí odkaz: https://doaj.org/article/c011bad7ab624a82a6a001263bf1db0c
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6
Clinical utility of serial serum dilutions for HLA antibody interpretation
Autor: Anat R. Tambur, Carrie Schinstock
Publikováno v: HLA. 100:457-468
Luminex single antigen bead (SAB) testing has increased the sensitivity and specificity of accurately identifying HLA antibodies, in support of all organ transplantation. However, as described in manufacturers' recommendation, the output of the assay
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1353172e33baf9dfe6b5c34a6372dd6f
https://doi.org/10.1111/tan.14781
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9
HLA-DQ mismatches lead to more unacceptable antigens, greater sensitization, and increased disparities in repeat transplant candidates
Autor: Dylan Isaacson, Jesse D. Schold, Michael W. Gmeiner, Hannah C. Copley, Vasilis Kosmoliaptsis, Anat R. Tambur
Background In single-center studies, HLA-DQ mismatches stimulate the most pathogenic donor-specific antibodies. However, because of limitations of transplant registries, this cannot be directly confirmed with registry-based analyses. Methods We evalu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f264e3b32d007b5ec926eb98d45659
http://eprints.lse.ac.uk/117649/
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10
Akademický článek
HLA-Epitope Matching or Eplet Risk Stratification: The Devil Is in the Details
Autor: Anat R. Tambur
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
“Epitope matching” became a trending topic in organ transplantation. In fact, discussions on clinical implementation and utilization of this approach in organ allocation algorithms are currently on-going. More recently, the term “eplet mismatch
Externí odkaz: https://doaj.org/article/fbd3cdeed512475dbaf6d6ca06ea7d29
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