Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anat Krauskopf"'
Publikováno v:
Current Genetics. 47:18-28
Eukaryotic cells invest a large proportion of their genome in maintaining telomere length homeostasis. Among the 173 non-essential yeast genes found to affect telomere length, a large proportion is involved in vacuolar traffic. When mutated, these va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b310083320568865e146cee40fa48f3d
https://doi.org/10.1007/s00294-004-0548-y
https://doi.org/10.1007/s00294-004-0548-y
Publikováno v:
Molecular Genetics and Genomics. 268:729-738
We report the identification and characterization of transcriptional silencing at native telomeres in the budding yeast Kluyveromyces lactis. We show that K. lactis telomeres are able to repress the transcription of a gene located at the junction bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57edd274b9819089a17ef38be3048df0
https://doi.org/10.1007/s00438-002-0788-9
https://doi.org/10.1007/s00438-002-0788-9
Publikováno v:
Molecular and Cellular Biology. 11:3515-3521
We have previously reported that both in vivo and in vitro, RNA polymerase II pauses or prematurely terminates transcription at a specific attenuation site located 142 to 147 nucleotides downstream from the P4 promoter of minute virus of mice (MVM).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330697676c54d492f2be0eb4d077f6b0
https://doi.org/10.1128/mcb.11.7.3515-3521.1991
https://doi.org/10.1128/mcb.11.7.3515-3521.1991
Role of the mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II
Publikováno v:
Molecular and Cellular Biology. 11:1195-1206
We have used a recently developed system that allows the isolation of complexes competent for RNA polymerase II elongation (E. Bengal, A. Goldring, and Y. Aloni, J. Biol. Chem. 264:18926-18932, 1989). Pulse-labeled transcription complexes were formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793af5dfa9d89d9da474448211e581f8
https://doi.org/10.1128/mcb.11.3.1195
https://doi.org/10.1128/mcb.11.3.1195
Autor:
Anamitra Bhattacharyya, David Gilley, T. Ware, Anat Krauskopf, Karen E. Kirk, John Prescott, Michael J. McEachern, Elizabeth H. Blackburn
Publikováno v:
Ciba Foundation Symposium 211 - Telomeres and Telomerase
The tandemly repeated DNA sequence of telomeres is typically specified by the ribonucleoprotein enzyme telomerase. Telomerase copies part of its intrinsic RNA moiety to make one strand of the telomeric repeat DNA. Recent work has led to the concept o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27d9190c1f7a61baf50e6cf0218e6934
https://doi.org/10.1002/9780470515433.ch2
https://doi.org/10.1002/9780470515433.ch2
Autor:
Sarit Smolikov, Syed H. Askree, Carrie Coker, Joshua D. Hawk, Martin Kupiec, Raya Gurevich, Anat Krauskopf, Tal Yehuda, Michael J. McEachern
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 101(23)
Telomeres are nucleoprotein structures present at the ends of eukaryotic chromosomes that play a central role in guarding the integrity of the genome by protecting chromosome ends from degradation and fusion. Length regulation is central to telomere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec50ac0fee077ab105878a2df60f871
https://pubmed.ncbi.nlm.nih.gov/15213325
https://pubmed.ncbi.nlm.nih.gov/15213325
Telomeres, the natural ends of eukaryotic chromosomes, prevent the loss of chromosomal sequences and preclude their recognition as broken DNA. Telomere length is kept under strict boundaries by the action of various proteins, some with negative and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce36f2ac127265555cc6b762c742ed2
https://europepmc.org/articles/PMC341813/
https://europepmc.org/articles/PMC341813/
Autor:
Elizabeth H. Blackburn, Christopher D. Smith, John Prescott, Anat Krauskopf, Michael J. McEachern, Tracy B. Fulton, H. Wang, J. Roy, J. Chang, Simon W. L. Chan
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 65
Multiple interacting components of the telomere, together with telomerase (and sometimes recombination), determine whether a telomere will be functional, allowing cell proliferation. The various components reinforce each other, providing for a robust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde6759a474b2b62c37d520da55f220a
https://pubmed.ncbi.nlm.nih.gov/12760039
https://pubmed.ncbi.nlm.nih.gov/12760039
Publikováno v:
Molecular biology of the cell. 12(10)
Telomeres, the natural ends of eukaryotic chromosomes, are essential for the protection of chromosomes from end-to-end fusions, recombination, and shortening. Here we explore their role in the process of meiotic division in the budding yeast, Kluyver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349289b18199013659a21869bae7e519
https://pubmed.ncbi.nlm.nih.gov/11598202
https://pubmed.ncbi.nlm.nih.gov/11598202
Publikováno v:
Annual review of genetics. 34
▪ Abstract Telomeres are DNA and protein structures that form complexes protecting the ends of chromosomes. Understanding of the mechanisms maintaining telomeres and insights into their function have advanced considerably in recent years. This revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13de3318b40d74b2c06b2e1e219554a9
https://pubmed.ncbi.nlm.nih.gov/11092831
https://pubmed.ncbi.nlm.nih.gov/11092831