Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anat Kohn"'
Autor:
Alayna E. Loiselle, Anat Kohn, Regis J. O'Keefe, Jennifer H. Jonason, Lea M. Gunnell, Edward M. Schwarz, Matthew J. Hilton
Publikováno v:
Journal of Bone and Mineral Research
The importance of canonical transforming growth factor β (TGF-β) and bone morphogenetic protein (BMP) signaling during cartilage and joint development is well established, but the necessity for noncanonical (SMAD-independent) signaling during these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd531af7a57a993aef6ccf495ee9ead5
https://doi.org/10.1002/jbmr.79
https://doi.org/10.1002/jbmr.79
Autor:
Anat Kohn, Timothy P. Rutkowski, Matthew J. Hilton, Yinshi Ren, Anthony J. Mirando, Deepika Sharma
Publikováno v:
Journal of Cell Science.
RBPjκ-dependent Notch signaling regulates multiple processes during cartilage development, including chondrogenesis, chondrocyte hypertrophy and cartilage matrix catabolism. Select members of the HES- and HEY-families of transcription factors are re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8872dd091a683e462dd753b7d287eb
https://doi.org/10.1242/jcs.181271
https://doi.org/10.1242/jcs.181271
Autor:
Matthew J. Hilton, Anthony J. Mirando, Regis J. O'Keefe, Michael J. Zuscik, Zhaoyang Liu, Timothy P. Rutkowski, Anat Kohn
Publikováno v:
Bone Research
RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0665ce8caabd7fa55d95b0643c9f9065
https://doi.org/10.1038/boneres.2015.21
https://doi.org/10.1038/boneres.2015.21
Autor:
Anat Kohn, Weidan Peng, Janet A. Sawicki, Robert Langer, Akin Akinc, Robert F. Padera, Naushad Hossain, Daniel G. Anderson
Publikováno v:
Proceedings of the National Academy of Sciences. 101:16028-16033
Optimal gene therapy for cancer must ( i ) deliver DNA to tumor cells with high efficiency, ( ii ) induce minimal toxicity, and ( iii ) avoid gene expression in healthy tissues. To this end, we generated a library of >500 degradable, poly(β-amino es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ee50fb7d138763483db71ee5820984
https://doi.org/10.1073/pnas.0407218101
https://doi.org/10.1073/pnas.0407218101
Autor:
Robert A. Mooney, Regis J. O'Keefe, Anat Kohn, Zhaoyang Liu, Michael J. Zuscik, Matthew J. Hilton, Alexandra Lang, Alana M. Osinski, Tyler Moore, Anthony J. Mirando
Publikováno v:
Arthritis & Rheumatism.
Objective Osteoarthritis (OA) is a degenerative disease resulting in severe joint cartilage destruction and disability. While the mechanisms underlying the development and progression of OA are poorly understood, gene mutations have been identified w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ef1f1fcd92d36c81b9dcda4ad043fa
https://doi.org/10.1002/art.38076
https://doi.org/10.1002/art.38076
Autor:
Anthony J, Mirando, Zhaoyang, Liu, Tyler, Moore, Alexandra, Lang, Anat, Kohn, Alana M, Osinski, Regis J, O'Keefe, Robert A, Mooney, Michael J, Zuscik, Matthew J, Hilton
Publikováno v:
Arthritis and rheumatism. 65(10)
Osteoarthritis (OA) is a degenerative disease resulting in severe joint cartilage destruction and disability. While the mechanisms underlying the development and progression of OA are poorly understood, gene mutations have been identified within cart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b52044d1c035e49c9dd9f810f11424f3
https://pubmed.ncbi.nlm.nih.gov/23839930
https://pubmed.ncbi.nlm.nih.gov/23839930
Autor:
Alana M. Jesse, Michael J. Zuscik, Tasuku Honjo, Anthony J. Mirando, Anat Kohn, Matthew J. Hilton, Regis J. O'Keefe, Yufeng Dong
The Notch signaling pathway has emerged as an important regulator of endochondral bone formation. Although recent studies have examined the role of Notch in mesenchymal and chondro-osteo progenitor cell populations, there has yet to be a true examina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2697cd215a2f15ba839b218d1b4065
https://europepmc.org/articles/PMC3283126/
https://europepmc.org/articles/PMC3283126/
Autor:
Lea M. Gunnell, Alana M. Jesse, Michael J. Zuscik, Anat Kohn, Yufeng Dong, Matthew J. Hilton, Tasuku Honjo, Regis J. O'Keefe
The Notch pathway has recently been implicated in mesenchymal progenitor cell (MPC) differentiation from bone marrow-derived progenitors. However, whether Notch regulates MPC differentiation in an RBPjkappa-dependent manner, specifies a particular MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3392c96454522d3b43ff542fda87c88e
https://europepmc.org/articles/PMC2853848/
https://europepmc.org/articles/PMC2853848/