Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anat Boehm-Cagan"'
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 1-11 (2018)
Abstract Introduction Alzheimer's disease (AD) and synucleinopathies share common pathological mechanisms. Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for AD, also increases the risk for dementia in pure synucleinopathies. We pr
Externí odkaz:
https://doaj.org/article/7bca9a669cd342b0b39800ccbc9de423
Autor:
Anat Boehm-Cagan, Roni Bar, Dror Harats, Aviv Shaish, Hana Levkovitz, John K Bielicki, Jan O Johansson, Daniel M Michaelson
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166195 (2016)
Apolipoprotein E4 (apoE4), the leading genetic risk factor for Alzheimer's disease (AD), is less lipidated compared to the most common and AD-benign allele, apoE3. We have recently shown that i.p. injections of the ATP-binding cassette A1 (ABCA1) ago
Externí odkaz:
https://doaj.org/article/e7ac0f8c755248ca9de611fed2609c35
Autor:
Lauren T. Hotaki, Anu Shrestha, Monica P. Bennett, Ivelisse L. Valdes, Sso H. Lee, Yinghua Wang, Dianne Spillman, Tina MacAulay, Melissa Hunt, Julie Gervais, Maral Mafi, Vincent Panetta, Yee Hoo Looi, Michael Shum, Eiman Atiek, Ricarda Meincke, Ulrich-Peter Rohr, Denize Ainbinder, Anat Boehm-Cagan, Osnat Luxenburg, Mateus Rodrigues Cerqueira, Laila Sofia Mouawad, Maria Fernanda Reis e Silva Thees, Krishna Prasad, R. Angelo de Claro
Publikováno v:
Therapeutic Innovation & Regulatory Science.
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 1-11 (2018)
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Introduction Alzheimer's disease (AD) and synucleinopathies share common pathological mechanisms. Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for AD, also increases the risk for dementia in pure synucleinopathies. We presently e
Autor:
Daniel M. Michaelson, Shiran Salomon-Zimri, Ishai Luz, Hila Ben-Moshe, Anat Boehm-Cagan, Ori Liraz
Publikováno v:
Journal of molecular neuroscience : MN. 70(1)
The ɛ4 allele of apolipoprotein E (apoE4) is the most prevalent genetic risk factor for Alzheimer’s disease. ApoE4 is also associated with poor recovery and functional outcome following traumatic brain injury. This study examined the effects of th
Autor:
Anat Boehm-Cagan, Daniel M. Michaelson, Ori Liraz, Daniel Offen, Shiran Salomon-Zimri, Yael Barhum, Tali Ben-Zur, Micaela Johanna Glat, Ishai Luz
Publikováno v:
Journal of Alzheimer's Disease. 53:1443-1458
Apolipoprotein E4 (ApoE4), the most prevalent genetic risk factor for Alzheimer's disease (AD), is associated with increased neurodegeneration and vascular impairments. Vascular endothelial growth factor (VEGF), originally described as a key angiogen
Autor:
Hussein N. Yassine, Mary Jo LaDu, Bengt Winblad, Daniel M. Michaelson, John K. Bielicki, Anat Boehm-Cagan, Henrik Zetterberg, Jan O. Johansson
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
John K. Bielicki, Varun Rawat, Jan Johansson, Anat Boehm-Cagan, Michael G. Harrington, Helena C. Chui, Hussein N. Yassine, Daniel M. Michaelson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Background: Loss-of-function mutations in the ATP Binding Cassette A-1 (ABCA-1) transporter and the ApoE4 allele are associated with increased Alzheimer’s disease (AD) risk. We recently reported decreased ABCA-1 activity of cerebrospinal fluid (CSF
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Background: Apolipoprotein E4 (apoE4) is associated with perturbed lipid metabolism and elevated risk for CVD and Alzheimer’s disease (AD). Data suggests impact of both non-brain and brain apoE on risk to develop AD. Homozygosity for apoE4 increase