Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anastazija Gnjec"'
Autor:
Seyed Mehrdad Savar, Bin Ma, Eugene Hone, Farzana Jahan, Shaun Markovic, Steve Pedrini, Soudabeh Shemehsavar, Vandhana Easwaran, Kevin Taddei, Samantha Gardener, Jasmeer P. Chhatwal, Ellis S. van Etten, Matthias J. P. van Osch, Daniel Clarke, Anastazija Gnjec, Mark A. van Buchem, Marieke J. H. Wermer, Graeme J. Hankey, Steven M. Greenberg, Ralph N. Martins, Hamid R. Sohrabi
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Cerebral amyloid angiopathy (CAA) is a type of cerebrovascular disorder characterised by the accumulation of amyloid within the leptomeninges and small/medium-sized cerebral blood vessels. Typically, cerebral haemorrhages are one of the first clinica
Externí odkaz:
https://doaj.org/article/bfd8f63dee3c43e9a9ba2bf6c9ec6b01
Autor:
Susanna Sunram-Lea, Stephanie J. Fuller, Eugene Hone, David Nolan, Anastazija Gnjec, Sam Gandy, Ian Martins, Ralph N. Martins, Jonathan K. Foster
Publikováno v:
Molecular Psychiatry. 11:721-736
High fat diets and sedentary lifestyles are becoming major concerns for Western countries. They have led to a growing incidence of obesity, dyslipidemia, high blood pressure, and a condition known as the insulin-resistance syndrome or metabolic syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8883b1c15c091135fa7e898ad486f94
https://doi.org/10.1038/sj.mp.4001854
https://doi.org/10.1038/sj.mp.4001854
Autor:
Pankaj D. Mehta, Elizabeth A. Milward, Justine A. Fonte, Byron Kakulas, Ricky R. Lareu, Gerald Veurink, David Lim, Judith Miklossy, Anastazija Gnjec, N. Tan, Giuseppe Verdile, Ralph N. Martins, Arunasalam Dharmarajan, Kristyn A. Bates
Publikováno v:
Neurology. 63:1385-1392
Objective: To compare proteins related to Alzheimer disease ( AD) in the frontal cortex and cerebellum of subjects with early-onset AD (EOAD) with or without presenilin 1 (PS1) mutations with sporadic late-onset AD ( LOAD) and nondemented control sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa29c1fcbd5329f7a387e19aedc6391
https://doi.org/10.1212/01.wnl.0000141848.45315.a6
https://doi.org/10.1212/01.wnl.0000141848.45315.a6
Autor:
Kevin Taddei, Justin Fonte, Francoise Suard, Christopher M. Fisher, Domizio Suva, Catriona McLean, Pankaj D. Mehta, Anastazija Gnjec, Colin L. Masters, Judith Miklossy, Joseph Ghika, William S. Brooks, Ralph N. Martins, Giuseppe Verdile
Publikováno v:
Neurobiology of Aging. 24:655-662
Mutations in the gene encoding presenilin 1 (PS-1) account for 50% of early-onset familial Alzheimer’s disease (EOFAD) cases. In this study, we identified two missense mutations in the coding sequence of the presenilin (PS-1) gene in two EOFAD pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc4280ccbaeaef182c8273991360314
https://doi.org/10.1016/s0197-4580(02)00192-6
https://doi.org/10.1016/s0197-4580(02)00192-6
Autor:
D. Allan Butterfield, Anastazija Gnjec, Jon B. Klein, William M. Pierce, Alessandra Castegna, H. Fai Poon, Ralph N. Martins
Publikováno v:
Journal of Alzheimer's disease : JAD. 10(4)
Objective: To identify oxidatively modified proteins in brains of persons with inherited Alzheimer's disease. Methods: Redox proteomics was used to identify oxidatively modified brain proteins in persons with mutations in the genes for presenilin-1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e794fd6325fa39f6a3a87ac1b8b9177
https://pubmed.ncbi.nlm.nih.gov/17183150
https://pubmed.ncbi.nlm.nih.gov/17183150
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 7
A defining feature of Alzheimer's disease (AD) pathology is the presence of amyloid beta known as A-beta (Abeta) within neuritic plaques of the hippocampus and neocortex of the brain. While early in vitro studies suggested that Abeta could itself be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035f0aec4f4900af083df24d5d655c8a
https://pubmed.ncbi.nlm.nih.gov/11897554
https://pubmed.ncbi.nlm.nih.gov/11897554
Autor:
G. Anthony Broe, Katarzyna J D'Costa, Giuseppe Verdile, Kevin Taddei, Judith Miklossy, Sam Gandy, Georgia Martins, Hayley P. Bennett, Patrick L. McGeer, Athena Paton, Ross Hedley, Anastazija Gnjec, Olivier Piguet, Kelvin Balakrishnan, Patricia Price, Joachim Hallmayer, William S. Brooks, Ralph N. Martins, Simon M. Laws
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 5, Iss 1, p 36 (2008)
Journal of Neuroinflammation, Vol 5, Iss 1, p 36 (2008)
BackgroundInflammatory changes are a prominent feature of brains affected by Alzheimer's disease (AD). Activated glial cells release inflammatory cytokines which modulate the neurodegenerative process. These cytokines are encoded by genes representin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16894cde5e2db1959947a31505d3607d